Targeted Ablation of <i>Crb1</i> and <i>Crb2</i> in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis by Lucie P. Pellissier (243199)

“…Loss of CRB1 and CRB2 result in altered progenitor cell cycle distribution with a decrease in number of late progenitors in G1 and an increase in S and G2/M phase. …”

Data_Sheet_10_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

“…Therefore, our results explain one underlying mechanism of increasing the sensitivity of osteosarcoma to chemotherapy and suggest that Sestrin2 is a promising gene target.</p>…”

Altered TRPV1 staining is observed in DRG obtained from STZ-induced diabetic mice by Reddy M Pabbidi (44094)

“…Representative TRPV1 immunofluorescent pictures of DRG sections from control non-diabetic (a), STZ-induced diabetic hyperalgesic (b), hypoalgesic mice (c) and non-diabetic TRPV1 knock-out mice (d). . …”

Computational Insights into the Conformational Accessibility and Binding Strength of SARS-CoV‑2 Spike Protein to Human Angiotensin-Converting Enzyme 2 by Cheng Peng (118834)

“…Experimental studies have shown the stronger binding affinity of the RBD (receptor binding domain) of CoV-2-S to angiotensin-converting enzyme 2 (ACE2) as compared to that of SARS-CoV spike (CoV–S). However, a similar or weaker binding affinity of CoV-2-S compared to that of CoV–S is observed if entire spikes are used in the bioassay. …”

Table_1_An Item-Level Analysis for Detecting Faking on Personality Tests: Appropriateness of Ideal Point Item Response Theory Models.docx by Jie Liu (15128)

“…This study modeled the responses of personality tests using ideal point method across instructed faking and honest responding conditions. A sample of undergraduate students participated the within-subjects measures to examine how the item location parameter derived from the generalized graded unfolding model changed, and how individuals’ perception about items changed when faked. …”

Linking potential biodiversity and three ecosystem services in silvopastoral managed forest landscapes of Tierra del Fuego, Argentina by Guillermo Martínez Pastur (3604106)

“…<p>Several studies confirm that biodiversity loss endangers ecosystem services (ES) supply and human well-being. A better understanding of biodiversity–ES relationships and effects of biodiversity loss on ES supply is needed. …”

Release of Organochlorine Pollutants from Forest Fires: 1. Emission Factors and Revisiting Their Emissions in the Himalayan Regions by Hong Xu (71477)

“…Worldwide forest fires have occurred frequently in recent years, a result of which may be the emission of so-called “legacy” organochlorine pollutants (OCPs) accumulated in forests. …”

Multiomics Analysis Revealed Colorectal Cancer Pathogenesis by Yong-Jiang Xu (1772092)

“…Fecal metabolomics analysis exhibited consistent increases in bile acids, indoles, and urobilin as well as a decrease in heme. Serum metabolomics uncovered the highest levels of bilin, glycerides, and nucleosides together with the lowest levels of bile acids and amino acids in the stage of intermediate lesions. …”

DARTS-VAN model unit search process. by Yuxuan Ji (13991895)

“…The runtime memory usage on the CIFAR-100 dataset is only 44.52%, a decrease of 44.56% compared to the baseline model. …”

What do Cochrane systematic reviews say about probiotics as preventive interventions? by Vinícius Lopes Braga (4704595)

“…<div><p>ABSTRACT BACKGROUND: Probiotics have been used for a range of clinical situations and their use is strongly encouraged by the media worldwide. …”

Anti-autophagic property of lutein was involved in mTOR-mediated autophagy pathway. by Frederic K. C. Fung (164563)

“…<p><b>(A)</b> Western blotting and the densitometric analysis showed that the phosphorylated AMPK was up-regulated in CoCl₂-treated cells. …”

Data_Sheet_3_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

“…Therefore, our results explain one underlying mechanism of increasing the sensitivity of osteosarcoma to chemotherapy and suggest that Sestrin2 is a promising gene target.</p>…”

<i>In Vitro</i> Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells by Rosyana V. Albuquerque (784417)

“…Theoretical calculations using density functional theory methods showed that DDS-NHOH has a pro-oxidant effect, whereas RSV and MET have antioxidant effect on ROS. …”

Influence of the use of testosterone associated with physical training on some hematologic and physical parameters in older rats with alloxan-induced diabetes by Romeu Paulo Martins Silva (6142499)

“…The NT and DT groups received application of testosterone twice a week. At the end of the sessions, the animals were subjected to swimming until exhaustion and then killed for removal of blood and visceral fat. …”

Image_1_Soil Microbial Populations Shift as Processes Protecting Organic Matter Change During Podzolization.JPEG by Marie-Liesse Vermeire (5512499)

“…Here, we assess the reciprocal interactions between soil minerals, SOM and the broad composition of microbial populations in a 530-year chronosequence of podzolic soils. Five pedons, derived from beach sand, are studied. …”

Exposure to environments with different norms changes participants’ behavior. by Claire Lugrin (21156528)

“…<p><b>(a)</b> Experiment 4 protocol. Timeline of the different tasks, and example trial for the frequent prosocial action environment. …”

Data_Sheet_1_How personal values follow the societal lockdown due to COVID-19: Case of business students in Slovenia.pdf by Vojko Potocan (15293377)

“…Contrary to previous publications, our results indicate a decrease of mean-level for all four higher-order groups of individuals’ values during societal lockdown of COVID-19. …”

Ripened Pu-erh Tea Extract Protects Mice from Obesity by Modulating Gut Microbiota Composition by Xiaojie Lu (1317612)

“…This study aims to explore the role of alterations in gut microbes mediated by ripened Pu-erh tea extract in obese mice through 16S rRNA sequencing and a fecal transplant trial. Our results suggested that drinking water containing ripened Pu-erh tea extract could decrease weight gain, fat accumulation, adipose inflammation, the Firmicutes-to-Bacteroidetes ratio, and metabolic endotoxemia while, in the meantime, improving the intestinal barrier integrity in obese mice. …”

Data_Sheet_3_MicroRNA 3′ ends shorten during adolescent brain maturation.FASTA by Kristen T. Thomas (15288109)

“…We conclude that age-associated miRNA 3′ shortening is a well-conserved feature of postnatal brain maturation.…”

Analyse vehicle–pedestrian crash severity at intersection with data mining techniques by Siying Zhu (459098)

“…To address the safety concern, this paper investigates the contributing factors to the severity of vehicle–pedestrian crashes at intersections based on a 3-year crash dataset of Hong Kong. For the crash severity modelling process, the crash dataset is mass and complicated. …”