<i>Lp</i> knockdown significantly impairs oogenesis and affects Vg expression and localization. by Iryna Stryapunina (17867390)

“…(C) Western blot quantification from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011145#pgen.1011145.g001" target="_blank">Fig 1C</a> showing an accumulation of Vg in the fat body and a decrease of Vg in the ovaries upon <i>Lp</i> knockdown; samples of five tissues, three biological replicates (REML variance component analysis: ** = p < 0.01; **** = p < 0.0001). …”

Inclusion and exclusion criteria. by Laurence Weinberg (2960238)

“…Scoping review registered on OSF registries (<a href="https://osf.io/4mg7n" target="_blank">https://osf.io/4mg7n</a>).…”

Table 1_Evaluation of F18 enterotoxigenic Escherichia coli intestinal attachment and early disease onset in nursery pigs.docx by Elizabeth M. Due (22819034)

“…Introduction<p>Enterotoxigenic Escherichia coli (ETEC) is a major cause of post-weaning diarrhea and reduced performance in nursery pigs. …”

DataSheet5_An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages.xlsx by Fei Jing (298892)

“…Fuzheng Huayu (FZHY) formula, a Chinese herbal product, is effective in treating pulmonary fibrosis in our previous study. …”

Image_2_Addition of Fibroblast-Stromal Cell Markers to Immune Synovium Pathotypes Better Predicts Radiographic Progression at 1 Year in Active Rheumatoid Arthritis.tif by Xue-Pei Zhang (10650773)

“…Objectives<p>This study aims to investigate if addition of fibroblast-stromal cell markers to a classification of synovial pathotypes improves their predictive value on clinical outcomes in rheumatoid arthritis (RA).…”

Knockdown of Ice-Binding Proteins in <i>Brachypodium distachyon</i> Demonstrates Their Role in Freeze Protection by Melissa Bredow (3396572)

“…IBP-knockdown lines also demonstrated a significant decrease in viability following freezing to −8°C, with some lines showing only two-thirds the survival seen in control lines. …”

DataSheet8_Transcriptional time course after rotator cuff repair in 6 month old female rabbits.XLSX by Laura S. Vasquez-Bolanos (11242737)

“…Many were also significantly enriched at 2 weeks, with the addition of NIF/NF-kappaB signaling, transcription in response to hypoxia, and mRNA stability alongside many additional pathways. There was also a shift in transcriptional activity at 4 weeks post-repair with significantly enriched pathways for lipids, hormones, apoptosis, and cytokine activity, despite an overall decrease in the number of differentially expressed genes. …”

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... by Aya Miyagawa-Hayashino (386487)

“…Pretreatment with JTE-013 reversed the TCA- or S1P2-mediated decrease in <i>ROCK1</i> expression. (E) <i>RHOA</i> mRNA expression exhibited a tendency similar to that of <i>ROCK1</i>. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes by Chet Raj Ojha (4258624)

“…The expression of toll-like receptor 3 (TLR3) was significantly increased with all three strains of ZIKV; pharmacological and genetic inhibition of TLR3 caused a decrease in viral titers and in viral-induced inflammatory response in infected astrocytes. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Data_Sheet_1_Prevalence and Prognosis of HFimpEF Developed From Patients With Heart Failure With Reduced Ejection Fraction: Systematic Review and Meta-Analysis.docx by Yibo He (4805139)

“…</p><p>Conclusion: Around 22.64% of patients with HFrEF would be treated to become HFimpEF, who would then obtain a 56% decrease in mortality risk. Meanwhile, HFimpEF is associated with lower heart failure hospitalization. …”

Pyrroloquinoline Quinone Resists Denervation-Induced Skeletal Muscle Atrophy by Activating PGC-1α and Integrating Mitochondrial Electron Transport Chain Complexes by Yung-Ting Kuo (736349)

“…The C57BL6/J mouse was subjected to a hindlimb sciatic axotomy. A PQQ-containing ALZET® osmotic pump (equivalent to 4.5 mg/day/kg b.w.) was implanted subcutaneously into the right lower abdomen of the mouse. …”

Presentation_1_Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease.pptx by Chun-Shu Wong (6750368)

“…CD4:CD8 and CD4 T- and B-cell PB subsets partly normalized compared to HC post-ART as viral load decreased. Strikingly in LN, ART led to a rapid decrease in interferon signaling pathways and an increase in Tfh, germinal center and IgD^-CD27^- B cells, consistent with histological findings of post-ART follicular hyperplasia. …”

DataSheet6_An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages.xlsx by Fei Jing (298892)

“…Fuzheng Huayu (FZHY) formula, a Chinese herbal product, is effective in treating pulmonary fibrosis in our previous study. …”

Data_Sheet_1_The 1-aminocyclopropane-1-carboxylic acid deaminase-producing Streptomyces violaceoruber UAE1 can provide protection from sudden decline syndrome on date palm.pdf by Khawla J. Alwahshi (13158522)

“…Thus, the number of conidia of Fs recovered from plants pre-treated with both BCAs was comparable, but significantly (P < 0.05) reduced compared to plants without any BCA treatment. In addition, a significant (P < 0.05) decrease in ACC levels of both the root and shoot tissues was detected inSv + Fs seedlings to almost similar levels of healthy seedlings. …”

Video1_Balancing welfare and habitat damage in pigs (Sus scrofa) under extensive farming: an ethological approach for determining the effects of group composition and environmental... by Edoardo Collarini (10146350)

“…In enrichment conditions with straw, we found a significant decrease in anxiety-related, affiliation, and excavation behaviours levels, and a significant increase in non-invasive exploration behaviours. …”

Resistance of genetically engineered <i>Rel</i>2-expressing immune-enhanced by Yuemei Dong (17509)

“…Detailed statistical information of infection assays with N, range, prevalence, <i>p</i>-values of prevalence determined by Chi-square test, median (with or without zeros), <i>p</i>-values of infection intensity (with or without zeros) calculated through Kruskal-Wallis and Mann-Whitney tests, and % decrease of oocysts, ookinetes, or sporozoites loads are presented in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002458#ppat.1002458.s008" target="_blank">Table S3</a>.…”

image1_Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson’s Disease: An In Silico and I... by Babita Singh (811405)

“…Treatment with BME before or after MPTP administration has a protective effect on dopaminergic neurons, as evidenced by a significant decrease in GFAP immunostaining and expression of inducible nitric oxide synthase (iNOS) in the substantia nigra region; however, the degree of improvement was more prominent in mice receiving BME treatment before MPTP administration. …”

Data Sheet 5_Global trends in ambient particulate matter-attributable ischemic heart disease among the elderly (1990–2021).csv by Yangxi Zeng (20710481)

“…Although BAPC projections indicate a continued decline, a potential rise in pollution around 2035 may slow the rate of decrease or temporarily flatten the downward trajectory.…”