The ADMET analysis of the selected compounds. by Ali Alisaac (14658440)

“…RMSF analysis indicated greater flexibility in ligand-binding regions of LasI-Sulfaperin and QscR complexes, suggesting weaker binding. SASA showed a decrease in solvent-accessible surface area for the LasI-Sulfamerazine complex, supporting a compact structure. …”

DataSheet2_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.PDF by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

DataSheet1_Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita.PDF by Concetta Altamura (13232397)

“…Membrane biotinylation assays and western blot were performed to support electrophysiological results. A531V and V947E mutations caused a decrease in chloride current density due to a reduction of ClC-1 total protein level and channel expression on the plasma membrane. …”

Data_Sheet_1_Inhibitory Effects of Dietary N-Glycans From Bovine Lactoferrin on Toll-Like Receptor 8; Comparing Efficacy With Chloroquine.PDF by Susana Figueroa-Lozano (8825519)

“…The inhibition of TLR-8 in MoDCs resulted in a significant decrease of IL-6 when cells were treated with the unmodified (0.5-fold, p < 0.0001), partially demannosylated (0.3-fold, p < 0.0001) and partially desialylated (0.4-fold, p < 0.0001) N-glycans. …”

Metal–Ligand Cooperativity via Exchange Coupling Promotes Iron- Catalyzed Electrochemical CO₂ Reduction at Low Overpotentials by Jeffrey S. Derrick (1474618)

“…Here, we report a molecular iron­(II) system that captures this design concept in a homogeneous setting through the use of a redox non-innocent terpyridine-based pentapyridine ligand (tpyPY2Me). …”

AMDET profiling parameters and shorting criteria. by Ali Alisaac (14658440)

“…RMSF analysis indicated greater flexibility in ligand-binding regions of LasI-Sulfaperin and QscR complexes, suggesting weaker binding. SASA showed a decrease in solvent-accessible surface area for the LasI-Sulfamerazine complex, supporting a compact structure. …”

Characteristics of each landscape type, including region, mean elevation, mean annual air temperature (MAAT), air freezing degree days (FDD), air thawing degree days (TDD), and fre... by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

Table_2_Correlation between dietary factors and Parkinson’s disease revealed by the analysis of Mendelian randomization.XLSX by Shan Zeng (3464564)

“…Employing MR, specifically the IVW method, revealed a significant inverse association between bap intake and gut microbiota, marked by an 8.010-fold decrease in Parabacteroides goldsteinii per standard deviation increase in bap intake (95% CI 1.005–63.818, p = 0.049). …”

Supplementary Material for: The Adapted Lifestyle-Integrated Functional Exercise Program for Preventing Functional Decline in Young Seniors: Development and Initial Evaluation by Schwenk M. (4149757)

“…<b><i>Methods:</i></b> Based on a conceptual framework, a multidisciplinary expert group developed an initial aLiFE version, including activities for improving strength, neuromotor performances, and PA. …”

HS delays the [K⁺]_o event and speeds recovery by increasing the rate of [K⁺]_o clearance. by Corinne I. Rodgers (37539)

“…<p>A. Time to recovery was positively correlated with failure temperature in CON and HS locusts (N_CON = 13; N_HS = 15). …”

Image_1_Impact of in-utero exposure to HIV and latent TB on infant humoral responses.tif by Kimberly J. S. Hjelmar (18890608)

“…All infants showed a decrease in IgG to viral antigens (HIV GP120 and HA) from 12 to 44 weeks attributed to waning of maternally transferred antibody titers. …”

Macrophages Have Distinct Transcriptional Responses to Vacuolar and Cytosolic L. monocytogenes Infection by Jess H Leber (4401)

“…Red indicates an increase in RNA abundance relative to uninfected macrophages, and green indicates a decrease. Genes identified by SAM and at least 4-fold induced in WT macrophages by <i>hly− L. monocytogenes</i> are indicated as targets of the “Vacuolar Response”. …”

Detailed agreement between ¹³C CEST, smFRET, SAXS, and SEC elution profiles with the generalized Manning model corroborates pre-organization by Mg²⁺. by Susmita Roy (589965)

“…(i) Compaction of SAM-II as a function of [Mg²⁺] obtained from SEC elution profiles is consistent with a decrease in hydrodynamic radius (experimental data adapted from ref. 40), [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005406#pcbi.1005406.ref040" target="_blank">40</a>] in qualitative agreement with the observed folding transition in the average radius of gyration (Rg) obtained from equilibrium simulations at Mg_1/2≈6.0 mM.…”

DataSheet1_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.PDF by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Polyclonal HSV-2 IgG antibody response elicited by HSV-2 0ΔNLS, gD-2, or control immunogens. by William P. Halford (202208)

“…<p>(<b>A</b>) Mean ± sem neutralizing antibody titer of Day 60 serum samples (n = 20 per group). …”

Cost-utility of 20-valent pneumococcal conjugate vaccine compared to no vaccination and recommended alternative vaccines among Belgian adults by Sophie Marbaix (5488280)

“…This cost-effectiveness analysis indicates that use of PCV20 will help decrease the number of pneumococcal disease cases, hospitalizations, and premature deaths at an affordable healthcare cost: PCV20 is a cost-effective option compared to no vaccination and a cost-saving option compared to the sequential regimen PCV15 followed by PPV23 in the Belgian adult population recommended for pneumococcal vaccination.…”

DataSheet3_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.PDF by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Image_2_Impact of in-utero exposure to HIV and latent TB on infant humoral responses.jpeg by Kimberly J. S. Hjelmar (18890608)

“…All infants showed a decrease in IgG to viral antigens (HIV GP120 and HA) from 12 to 44 weeks attributed to waning of maternally transferred antibody titers. …”

Table_1_Correlation between dietary factors and Parkinson’s disease revealed by the analysis of Mendelian randomization.XLSX by Shan Zeng (3464564)

“…Employing MR, specifically the IVW method, revealed a significant inverse association between bap intake and gut microbiota, marked by an 8.010-fold decrease in Parabacteroides goldsteinii per standard deviation increase in bap intake (95% CI 1.005–63.818, p = 0.049). …”

Reduction of BMP-signaling in <i>Fgf3</i> mutants partially rescues axis extension. by Matthew J. Anderson (265883)

“…<i>Fgf3</i>^<i>Δ/Δ</i><i>; Bmpr1b</i>^<i>Δ/Δ</i> compound mutants, compared to <i>Fgf3</i>^<i>Δ/Δ</i> mutants show a narrower, more normal neural tube at 28 ss (<b>B</b> compare to <b>A</b>; <b>black brackets</b> indicate measurement of NT width, quantified in <b>C</b>), a decrease in neuroectoderm proliferation as measured by phospho-histone H3 staining (<b>D</b>, 26–27 ss, n = 3 each, percentage represents positive nuclei per total nuclei), an increase in tailbud progenitors (<b>F</b> compare to <b>E</b>; <b>black arrows</b> denote tailbud progenitor domain) and a rostrally shifted, more normal, posterior limit of neural crest cells at 34 ss (<b>H</b> compare to <b>G</b>; <b>red arrows</b> indicate posterior limit of neural crest expansion and somites are marked by <b><i>Uncx4</i>.1</b> expression). …”