Modulation of human monocytes by exposure to mitochondrial DNA. by Irene Fernández-Ruiz (5653951)

“…<p>(<b>A</b>) Workflow diagram: MΦs from HV were pre-exposed to mitochondrial DNA isolated from HeLa (mtDNA, 5 µg/ml, white bars), LPS (10 ng/ml, gray bars) or left untreated (black bars) for 5 days, then stimulated for 24 h with LPS, as described in the scheme. …”

Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease by Anna Alisi (139476)

“…FGF21 and FGF19 showed a tendency to decrease from CTRL (median FGF21 = 196 pg/mL; median FGF19 = 201 pg/mL) to NASH− (FGF21 = 89 pg/mL; FGF19 = 81 pg/mL) to NASH+ patients (FGF21 = 54 pg/mL; FGF19 = 41 pg/mL) (<i>p</i><0.001 for all comparisons) and were inversely associated with the probability of NASH and fibrosis in children with NAFLD. …”

DataSheet_3_Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis.csv by Wenjuan Qian (3909184)

“…<p>Temperature affects seed germination and seedling growth, which is a critical and complex stage in plant life cycle. …”

Data Sheet 1_An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.pdf by Yang Xiao (146335)

“…For both primary and secondary infections, oral immunization with LL-plSAM-GILE led to a significant decrease in the diameter and weight of hepatic cysts.…”

Image 1_Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19.pdf by Aurelie Guironnet-Paquet (15407171)

“…</p>Methods<p>In this study, we set up a prospective, randomised clinical trial (ClinicalTrials.gov ID: NCT04751643) and performed therapeutic plasma exchange (TPE) in severe COVID-19 patients in order to decrease excess cytokines and auto-antibodies and to assess whether adding TPE to the standard treatment (ST, including corticosteroids plus high-flow rate oxygen) could help restore immune parameters and limit the progression of acute respiratory distress syndrome (ARDS).…”

Model performance evaluation results. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”

Modulation of insulin degrading enzyme activity and liver cell proliferation by Olga Pivovarova (735300)

“…<p>Diabetes mellitus type 2 (T2DM), insulin therapy, and hyperinsulinemia are independent risk factors of liver cancer. Recently, the use of a novel inhibitor of insulin degrading enzyme (IDE) was proposed as a new therapeutic strategy in T2DM. …”

Interaction of FKBP8 with ER specific protein and FKBP8 expression in mitochondria fraction during mitophagy. by Michael O. Isei (20500908)

“…<p>Dual staining for FKBP8 (red) and BiP/GrP78 (green) was performed to analyze their colocalization in unstressed cells <b>(A)</b> and cells induced for mitophagy with PQ for 6 h <b>(B)</b>. …”

Table5_Integrative RNA-Seq and ATAC-Seq Analysis Reveals the Migration-Associated Genes Involved in Antitumor Effects of Herbal Medicine Feiyanning on Lung Cancer Cells.DOCX by Chenyang Wang (170127)

“…Traditional Chinese medicine formula Feiyanning has been clinically administered in China for more than a decade and raised attention due to its anticancer effect in lung cancer. …”

Image 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Table_1_Potentially differential impacts on niche overlap between Chinese endangered Zelkova schneideriana and its associated tree species under climate change.docx by Yanrong Zhou (4841061)

“…<p>Climate change has a significant impact on the potential distribution for endangered trees. …”

Individualized pattern recognition for detecting mind wandering from EEG during live lectures by Kiret Dhindsa (7378439)

“…We performed traditional group-level analysis and found neural correlates of mind wandering during live lectures that are similar to those found in some laboratory studies, including a decrease in occipitoparietal alpha power and frontal, temporal, and occipital beta power. …”

Exposure Assessment for Estimation of the Global Burden of Disease Attributable to Outdoor Air Pollution by Michael Brauer (675317)

“…The highest seasonal ozone levels were found in North and Latin America, Europe, South and East Asia, and parts of Africa. Between 1990 and 2005 a 6% increase in global population-weighted PM_2.5 and a 1% decrease in global population-weighted ozone concentrations was apparent, highlighted by increased concentrations in East, South, and Southeast Asia and decreases in North America and Europe. …”

Table_1_Dimethyl fumarate alleviates allergic asthma by strengthening the Nrf2 signaling pathway in regulatory T cells.xlsx by Yanhong Cen (18420282)

“…Histopathological analysis showed that DMF treatment in an OVA-induced animal model eased the inflammation in the nasal and bronchial tissues, with a particular decrease in the infiltration of immune cells. …”

Image_1_miR-344-5p Modulates Cholesterol-Induced β-Cell Apoptosis and Dysfunction Through Regulating Caveolin-1 Expression.tif by Xulong Sun (11195769)

“…<p>Diabetes is a metabolic disorder induced by the modulation of insulin on glucose metabolism, and the dysfunction and decreased number of islets β-cells are the main causes of T2DM (type 2 diabetes mellitus). …”

Presentation_1_Evolution of RAS Mutational Status in Liquid Biopsies During First-Line Chemotherapy for Metastatic Colorectal Cancer.pdf by Susanne Klein-Scory (83826)

“…All patients with PR or SD at first follow-up showed a significant decrease of RAS mutational load. …”

Image 6_Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19.jpeg by Aurelie Guironnet-Paquet (15407171)

“…</p>Methods<p>In this study, we set up a prospective, randomised clinical trial (ClinicalTrials.gov ID: NCT04751643) and performed therapeutic plasma exchange (TPE) in severe COVID-19 patients in order to decrease excess cytokines and auto-antibodies and to assess whether adding TPE to the standard treatment (ST, including corticosteroids plus high-flow rate oxygen) could help restore immune parameters and limit the progression of acute respiratory distress syndrome (ARDS).…”

Randomized double-blinded pilot clinical study of the antidiabetic activity of <i>Balanites aegyptiaca</i> and UPLC-ESI-MS/MS identification of its metabolites by Hend Rashad (4260301)

“…</p> <p><b>Results:</b> Thirteen compounds were identified in BE using UPLC-ESI-MS/MS analysis among which five steroidal saponins, seven phenolic compounds and a sterol glucoside. At the end of the 8-week treatment, the treated group showed 26.88% decrease in 2 h postprandial plasma glucose relative to 2.6% increase in the placebo group, while fasting plasma glucose was reduced to 10.3%. …”

Image_2_Antifungal, Plant Growth-Promoting, and Genomic Properties of an Endophytic Actinobacterium Streptomyces sp. NEAU-S7GS2.TIF by Dongli Liu (2580382)

“…These results suggested that strain NEAU-S7GS2 may be a potential biocontrol agent and biofertilizer used in agriculture.…”

Data_Sheet_1_Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophys... by Shun-Ho Huang (9322052)

“…Recognizing that the seal resistance formed by adhering-microglia to the implant constitutes a downstream element undermining extracellular FP recordings, suggests that approaches to mitigate the formation of the insulating glial could lead to improved recording quality and yield.…”