Table1_Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.DOCX by Yanzhen Chen (11498506)

“…Meanwhile, our results indicated that JPYZXZ inhibited the delivery of exosomal PD-L1 from GC cells to bone marrow cells, thereby alleviating exosomal PD-L1-induced differentiation and expansion of MDSCs in the tumor microenvironment. This led to a decrease in the levels of several immunosuppressive factors, including iNOS, Arg-1, TGF-β, IL-10, and IL-6, in 615-strain mice. …”

DataSheet_2_Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation thr... by Shi-Qian Liang (5569160)

“…In this study, with an 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) hydrochloride-induced acute murine PD model, we found that Notch signaling was activated in amoeboid microglia accompanied by a decrease in tyrosine hydroxylase (TH)–positive neurons. …”

Data declaration. by Mengting Jin (1888933)

“…By 2035, cropland, forest, water, and construction land areas are expected to increase, while grassland and unused land areas are projected to decrease. Under the ecological protection scenario, cropland, forest land, and grassland—major main contributors to carbon storage—will be effectively conserved to some extent. (2) From 2000 to 2020, Xinjiang’s carbon storage capacity exhibited an overall increasing trend, with a cumulative increase of 137.515×10⁵ t and a growth rate of 1.58%. …”

Table7_Chronic hypoxia disrupts T regulatory cell phenotype contributing to the emergence of exTreg-TH17 cells.xlsx by Benjamin J. Lantz (13008489)

“…These findings suggest that CH causes a decrease in Treg suppressive capacity, and exTregs respond to CH by transitioning to T_H17 cells, both of which tilt the Treg–T_H17 cell balance toward T_H17 cells, creating a pro-inflammatory environment.…”

Primers for qPCR. by Kaitao Zhao (3617825)

“…Likewise, the MRE11 endonuclease activity inhibitor PFM01 treatment decreased cccDNA. MRE11 nuclease assays indicated that rcDNA is a substrate of MRE11. …”

Image2_High Expression of ATP6V1C2 Predicts Unfavorable Overall Survival in Patients With Colon Adenocarcinoma.TIF by Guanghua Li (1415437)

“…</p><p>Results: ATP6V1C2 showed a significantly higher expression level in COAD compared with matched non-cancerous tissues. …”

Table1_Chronic hypoxia disrupts T regulatory cell phenotype contributing to the emergence of exTreg-TH17 cells.docx by Benjamin J. Lantz (13008489)

“…These findings suggest that CH causes a decrease in Treg suppressive capacity, and exTregs respond to CH by transitioning to T_H17 cells, both of which tilt the Treg–T_H17 cell balance toward T_H17 cells, creating a pro-inflammatory environment.…”

DataSheet_1_Arctic biogeochemical and optical properties of dissolved organic matter across river to sea gradients.pdf by Michael G. Novak (13582594)

“…The average DOC concentration at the multiple Yukon River mouths ranged from a high of 10.36 mg C L^-1 during the ascending limb of the 2019 freshet (late May), 6.4 mg C L^-1 during the descending limb of the 2019 freshet (late June), and a low of 3.86 mg C L^-1 during low river discharge in August 2018. …”

Effects of azilsartan compared with telmisartan on insulin resistance in patients with essential hypertension and type 2 diabetes mellitus: An open-label, randomized clinical trial by Mitsuhide Naruse (6551468)

“…</p><p>Trial registration</p><p>ClinicalTrials.gov <a href="https://clinicaltrials.gov/ct2/show/NCT02079805" target="_blank">NCT02079805</a></p></div>…”

Table_1_Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.DOCX by Fuu-Jen Tsai (230856)

“…Treatment of mice with Aba/Lam and Lop/Rit enhanced the lipid accumulation in the liver, and the decrease in AMP-activated protein kinase (AMPK) phosphorylation and/or its downstream target acetyl-CoA carboxylase (ACC) protein expression. …”

Image1_Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.JPEG by Yanzhen Chen (11498506)

“…Meanwhile, our results indicated that JPYZXZ inhibited the delivery of exosomal PD-L1 from GC cells to bone marrow cells, thereby alleviating exosomal PD-L1-induced differentiation and expansion of MDSCs in the tumor microenvironment. This led to a decrease in the levels of several immunosuppressive factors, including iNOS, Arg-1, TGF-β, IL-10, and IL-6, in 615-strain mice. …”

Statistics of simulated generalized Rouse polymer chain for various connectivity in one and two sub-regions. by Ofir Shukron (3900358)

“…<p><b>A</b>. Schematic bead-spring chain connected at random positions (two-sided green arrows) between non-nearest-neighbor monomers. …”

Estimated Daily Intake (EDI) in of heavy metals. by Zahra Alinezhad (17904302)

“…</p><p>Conclusion</p><p>The elevated levels of heavy metals in milk samples, especially Pb and Cd is a public health concern; therefore, maximum control and strict regulations must be adopted to decrease heavy metals contaminants in the dairy industry. …”

Table_1_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

image1_Changes in Efficacy Indicators for Adalimumab Biosimilar Candidate (HS016) for the Treatment of Active Ankylosing Spondylitis at Various Time Points.tif by Jinmei Su (4604059)

“…Among these indicators, chest expansion showed a significant increase at each time point compared with baseline, whereas all other efficacy indicators showed significant decreases compared with baseline at each time point (all p < 0.05). …”

DSB formation is altered in <i>dot-1</i>.<i>1</i> mutant worms. by Laura I. Lascarez-Lagunas (8275293)

“…Between 4 and 6 gonads were scored per genotype. A significant decrease in levels of RAD-51 foci were observed for zones 4 to 7 in <i>dot-1</i>.…”

Data_Sheet_1_The timelines for the price and reimbursement authorization in Italy 2018–2020.pdf by Valentina Gallo (95843)

“…In 2020, the overall process duration for Off-patent pharmaceuticals procedures was equal to 129.8 average days [95% CI: (122.3–137.2)], with a median value of 108.0, whereas for In-patent pharmaceuticals procedures, it was equal to 283.1 average days [95% CI: (267.8–298.5)], with a median value of 284.0. …”

The complete workflow employed in this study. by Md. Mostafa Kamal (13514317)

“…Furthermore, mCSM and DynaMut2 analyses indicated a decrease in ΔΔG stability for the mutants. GeneMANIA and STRING networks highlighted correlations with <i>CD86</i> and <i>CD80</i> genes. …”

Prognosis for Hospitalized Patients with Systemic Lupus Erythematosus in China: 5-Year Update of the Jiangsu Cohort by Xuebing Feng (293563)

“…<div><p>Objective</p><p>To identify early signs associated with poor prognosis in Chinese patients with systemic lupus erythematosus (SLE) through a large population-based follow-up study.</p><p>Methods</p><p>Medical records of > 2,500 SLE patients that first hospitalized between 1999–2009 were collected from 26 centers across Jiangsu province, China, and entered into a database. …”

Data_Sheet_1_Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition.pdf by Mayssa Albouery (8294364)

“…Gut colonization by microbiota of old mice resulted in a significant increase in total monounsaturated fatty acids (MUFA) and a significant decrease in the relative amounts of cholesterol and total polyunsaturated fatty acids (PUFA) in the cortex. …”