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144781
Table4_Chronic hypoxia disrupts T regulatory cell phenotype contributing to the emergence of exTreg-TH17 cells.XLSX
Published 2024“…These findings suggest that CH causes a decrease in Treg suppressive capacity, and exTregs respond to CH by transitioning to T<sub>H</sub>17 cells, both of which tilt the Treg–T<sub>H</sub>17 cell balance toward T<sub>H</sub>17 cells, creating a pro-inflammatory environment.…”
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144782
Target sequences of siRNAs.
Published 2025“…Likewise, the MRE11 endonuclease activity inhibitor PFM01 treatment decreased cccDNA. MRE11 nuclease assays indicated that rcDNA is a substrate of MRE11. …”
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144783
Image_1_Dynamic Zinc Accumulation and Contributions of Pre- and/or Post-Silking Zinc Uptake to Grain Zinc of Maize as Affected by Nitrogen Supply.pdf
Published 2019“…These results suggest that N nutrition is a critical factor for shoot Zn uptake and its allocation to maize grain. …”
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144784
Resistance to Systemic Inflammation and Multi Organ Damage after Global Ischemia/Reperfusion in the Arctic Ground Squirrel
Published 2014“…For HS, rats, AGS-EU, and winter interbout arousal AGS (AGS-IBA) were subject to HS by withdrawing blood to a mean arterial pressure of 35 mmHg and maintaining that pressure for 20 min before reperfusion with Ringers. …”
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144785
Combined <i>in vitro</i> IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis
Published 2020“…Further, the combinations rcaIL-12/rcaIL-2 and rcaIL-12/rcaIL-15 promoted a decrease in programmed cell death protein 1 (PD-1) expression in lymphocytes. …”
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144786
Plasmids information.
Published 2025“…Likewise, the MRE11 endonuclease activity inhibitor PFM01 treatment decreased cccDNA. MRE11 nuclease assays indicated that rcDNA is a substrate of MRE11. …”
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144787
S2 Data -
Published 2024“…<div><p>Background</p><p>Oral mucositis is an inflammatory condition of oral cavity which is a common and serious side effect of cancer treatment. …”
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144788
Image_4_Dynamic immune status analysis of peripheral blood mononuclear cells in patients with Klebsiella pneumoniae bloodstream infection sepsis using single-cell RNA sequencing.jp...
Published 2024“…</p>Results<p>During K. pneumoniae acute infection we observed a decrease in the proportion of T cells, most probably due to apoptosis and the function of T cell subtypes was disorder. …”
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144789
Presentation_1_Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma Growth.PPTX
Published 2020“…Taken together, these results demonstrate that the combination of NU7441 and olaparib with IR enhances HPV-negative HNSCC inhibition in both cell culture and in mice, suggesting a potential innovative combination for effectively treating patients with HPV-negative HNSCC.…”
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144790
Table_1_Modulation of the skin microbiome in cutaneous T-cell lymphoma delays tumour growth and increases survival in the murine EL4 model.xlsx
Published 2024“…Intriguingly, we observed a significant decrease in Staphylococcus aureus frequency (p = 0.0001) but an increase in the overall detection frequency of the Staphylococcus genus, indicating that antibiotic treatment helped regain the microbial balance and increased the number of non-pathogenic Staphylococcus populations. …”
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144791
DataSheet_1_Nationwide Trends of Pediatric Obesity and BMI z-Score From 2017-2021 in China: Comparable Findings From Real-World Mobile- and Hospital-Based Data.docx
Published 2022“…The trend of obesity prevalence remained stable with slight decrease, but COVID-19 lockdown caused a significant increase of 1.86% in 2020. …”
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144792
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144793
DataSheet_1_Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation thr...
Published 2023“…In this study, with an 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) hydrochloride-induced acute murine PD model, we found that Notch signaling was activated in amoeboid microglia accompanied by a decrease in tyrosine hydroxylase (TH)–positive neurons. …”
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144794
Raw data.
Published 2025“…Likewise, the MRE11 endonuclease activity inhibitor PFM01 treatment decreased cccDNA. MRE11 nuclease assays indicated that rcDNA is a substrate of MRE11. …”
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144795
14-3-3σ sequesters CyclinB1 in the cytoplasm in Cdc7-depleted HeLa cells.
Published 2012“…Co-depletion of 14-3-3σ led to a decrease in the overall CyclinB1 protein level (<b>C</b>), reduced cell death (<b>D</b>), and reduced the duration of its cytoplasmic retention (<b>E</b>).…”
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144796
IL-1α and IL-1β trigger fat tissue remodeling.
Published 2014“…The addition of supernatant from normal skin culture revealed a decrease in the number of plump adipocytes containing lipids as stained with oil red O, which was reversed by supplementing with supernatant from KCASP1Tg mice skin culture. …”
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144797
DataSheet_1_Identification of TSGA10 and GGNBP2 splicing variants in 5′ untranslated region with distinct expression profiles in brain tumor samples.docx
Published 2023“…The specific regulation of each gene can play a critical role in cancer progression. The present study aimed to determine the transcripts of the TSGA10 and GGNBP2 genes, considering the alternative 5′UTR region, and investigating the expression of these different transcripts in BTs.…”
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144798
Image_1_Interaction between peripheral blood mononuclear cells and Trypanosoma cruzi-infected adipocytes: implications for treatment failure and induction of immunomodulatory mecha...
Published 2024“…In contrast, there was a decrease in tumor necrosis factor (TNF) and IL-8/CXCL-8 in the groups with AT. …”
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144799
Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp.
Published 2017“…<div><p>Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of <i>Mikania variifolia</i> and <i>Mikania micrantha</i> dichloromethane extracts. …”
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144800
Table_1_CD19 CAR-T Cells With Membrane-Bound IL-15 for B-Cell Acute Lymphoblastic Leukemia After Failure of CD19 and CD22 CAR-T Cells: Case Report.docx
Published 2021“…Finally, on relapse of CD19<sup>−</sup> medullary disease, he received allogeneic humanized CAR22-41BB-CD3ζ-tEGFR-T cells but only achieved a transient decrease in the number of blasts. No CAR-T-cell-related encephalopathy syndrome was observed, and all side effects were manageable.…”