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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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18901
Image_1_Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway.TIF
Published 2019“…<p>It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases apoptosis in human cancer cell lines by NF-κB signaling pathway suppression. …”
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18902
Data_Sheet_1_Epinephrine May Contribute to the Persistence of Traumatic Memories in a Post-traumatic Stress Disorder Animal Model.pdf
Published 2020“…After induction of PTSD, Pnmt-KO mice showed a decrease in freezing, as well as an increase in open arm entries and transitions between compartments compared to WT. …”
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18903
Image_3_Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway.TIF
Published 2019“…<p>It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases apoptosis in human cancer cell lines by NF-κB signaling pathway suppression. …”
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18904
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18905
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18906
Synthesis of Triazole-Substituted Quinazoline Hybrids for Anticancer Activity and a Lead Compound as the EGFR Blocker and ROS Inducer Agent
Published 2018“…A series of triazole-substituted quinazoline hybrid compounds were designed and synthesized for anticancer activity targeting epidermal growth factor receptor (EGFR) tyrosine kinase. …”
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18907
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18908
Precursor B Cells Increase in the Lung during Airway Allergic Inflammation: A Role for B Cell-Activating Factor
Published 2016“…</p><p>Conclusion</p><p>Our data support the concept of a BAFF-mediated role for B cell precursors in allergic airway inflammation.…”
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18909
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18910
(modified from EDENetwork, [<b>75</b>]): Simplified network of <i>Trypanosoma cruzi</i> including stocks of near-clades I, II and III (respectively yellow, blue and green nodes) and scanned for decreasing thresholds from the (a) fully connected network (all pairwise links included) to the (b) percolation threshold (Dp, all links corresponding to distances superior to Dp excluded) and to (c) a lower threshold chosen to illustrate the sequential split of clusters at decreasing thresholds, and main properties of nodes and networks used herein.
Published 2014“…<p>(modified from EDENetwork, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103213#pone.0103213-Kivela1" target="_blank">[<b>75</b>]</a>): Simplified network of <i>Trypanosoma cruzi</i> including stocks of near-clades I, II and III (respectively yellow, blue and green nodes) and scanned for decreasing thresholds from the (a) fully connected network (all pairwise links included) to the (b) percolation threshold (Dp, all links corresponding to distances superior to Dp excluded) and to (c) a lower threshold chosen to illustrate the sequential split of clusters at decreasing thresholds, and main properties of nodes and networks used herein.…”
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18911
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18912
Image_1_Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model.TIF
Published 2018“…Previous studies have shown an association between ABCA1 deficiency and retinal inflammation. Using a mouse model of ischemia-reperfusion (IR) induced by acute intraocular pressure elevation, we found that the retinal expression of ABCA1 protein was decreased. …”
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18913
Effect of Treatment with Interferon Beta-1a on Changes in Voxel-Wise Magnetization Transfer Ratio in Normal Appearing Brain Tissue and Lesions of Patients with Relapsing–Remitting...
Published 2014“…</p><p>Methods</p><p>Increasing (suggestive of remyelination) and decreasing (suggestive of demyelination) VW-MTR changes in NABT and in T2, T1 and gadolinium (Gd)-enhancing lesion volume were measured over 24 weeks in 23 patients treated with IFN β-1a SC and in 15 HCs (where applicable). …”
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18914
Presentation_1_The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons.pdf
Published 2020“…Excess α-syn or fPD mutant α-syn<sup>A53T</sup> accumulates within larval axons perturbing the transport of synaptic proteins. …”
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18915
Presentation_1_The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons.pdf
Published 2020“…Excess α-syn or fPD mutant α-syn<sup>A53T</sup> accumulates within larval axons perturbing the transport of synaptic proteins. …”
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18916
The interaction between PSD95 and the NMDAR is transiently disrupted upon NMDAR stimulation.
Published 2014“…<p>(A) Two examples of confocal images of 14 DIV dendrites expressing GluN1-GFP (first column) and PSD95-mCherry (second column). …”
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18917
DataSheet1_Magnesium Isoglycyrrhizinate Ameliorates Concanavalin A-Induced Liver Injury by Inhibiting Autophagy.docx
Published 2022“…In vitro experiments also showed that MgIG reduced ConA-induced hepatocyte death but did not decrease hepatocyte apoptosis by inhibiting autophagy.…”
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18918
Image1_Hydroxy-Safflower Yellow A Alleviates Osteoporosis in Ovariectomized Rat Model by Inhibiting Carbonic Anhydrase 2 Activity.TIF
Published 2021“…<p>Background: To investigate the therapeutic effect of Hydroxy-safflower yellow A (HSYA) on rat’s osteoporosis and explore its potential mechanism of action.…”
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18919
Presentation1_Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction.pdf
Published 2022“…In addition, the expression of melatonin receptor 1A (Mtnr1a) in ovarian granulosa cells significantly decreased in the darkness group. …”
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18920
Allelic Variants in <i>Arhgef11</i> via the Rho-Rock Pathway Are Linked to Epithelial–Mesenchymal Transition and Contributes to Kidney Injury in the Dahl Salt-Sensitive Rat
Published 2015“…Genetic knockdown of <i>Arhgef11</i> in HEK293 and NRK resulted in reduced RhoA activity, decreased activation of Rho-ROCK pathway, and less stress fiber formation versus control, similar to what was observed by pharmacological inhibition (fasudil). …”