Image_4_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

Image_3_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

Supplementary Material for: Prenatal Infection Decreases Calbindin, Decreases Purkinje Cell Volume and Density and Produces Long-Term Motor Deficits in Sprague-Dawley Rats by Wallace K. (4120819)

“…Pups in the <i>E. coli</i> group also had a decrease in the number of Purkinje cells, as well as a decrease in Purkinje cell density and volume. …”

X‑ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson’s Disease Mouse Model by Jun Mou (4113313)

“…In a MPTP-induced Parkinson’s disease (PD) mouse model, <b>BI-43</b> manifested efficacy in mitigating locomotor deficits through reversing dopaminergic neuronal loss, reducing microglia, and decreasing levels of the sQC/gQC substrates, α-synuclein, and CCL2. …”

Architecture of early-combined model (Model (A)). by Wanchalerm Pora (8360934)

A block of diagram of the process of our method. by Shuting Liao (9524506)

Raw data as basis for a meta-analysis. by Chan Guo (6116351)

A visual summary of the key study findings. by Joachim Worthington (8394213)

“…These changes would lead to an estimated increase of 255 colorectal cancer cases and 1,820 colorectal cancer deaths in Canada and 234 cases and 1,186 deaths in Australia over 2020–2030; a 1.9% and 2.4% increase in mortality, respectively, vs a scenario with no screening disruption or diagnostic/treatment delays. …”

A: Reduced image; B: Focal area. by Shuting Liao (9524506)

Cinnamaldehyde is a specific ligand for HL-IR. by Ceyan Kuang (8554557)

“…The ratio of bound/free 1-NPN gradually decreased as the concentration of 1-NPN increased, accompanied by a corresponding rise in fluorescence intensity. …”

Number of pulmonary endothelial cells decreased upon infection and started to proliferate during resolution to restore their number by 15 dpi accompanied by decreased endothelial a... by Emilie Pollenus (10147748)

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…<p><b>A,B:</b> Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. …”

Evolution of the four pre-stimuli psychological parameters (A: Valence, B: Arousal, C: Tension, D: Energy). by Felix Alexandre Schoeller (20988295)

Quiescent amastigotes exhibit a significantly reduced size compared to DsRed^hi amastigotes. by Laura Dirkx (8950205)

PK profiles of the developed nanoparticles vs. free drugs in rats (a) amlodipine, (b) hydrochlorothiazide, and (c) candesartan. by Anjuman Arora (750291)

A. Bar chart showing the percentage of participants experiencing chills in response to various stimuli, ordered by descending frequency. by Felix Alexandre Schoeller (20988295)

“…<p>B: Line graph indicating a decrease in the chills ratio over successive presentations of stimuli, with a marked drop between the fifth and sixth exposure. …”

FBG1 knockout increases A1AT-Z dPAS accumulation in the mouse liver. by John H. Wen (785980)

Knockdown of FBG1 in HepG2 cells increases levels of endogenous A1AT. by John H. Wen (785980)

Adult female tree crickets <i>Oecanthus nigricornis</i> with <i>a)</i> few ovarian eggs and <i>b)</i> an abdomen full of ovarian eggs; <i>c)</i> Predaceous wasp <i>Isodontia mexica... by Kyla Ercit (645474)

Aβ₄₂-induced proteasome inhibition is associated with a delayed, inverse effect on CatB activity. by Karen L. G. Farizatto (4348537)