Effect of native (hOb) and Q90L obestatin (hObQ90L) on the ghrelin-induced (Ghr) decrease of evoked GABA synaptic responses in GHRH neurons. by Rim Hassouna (113060)

ΔR₂* (s⁻¹) in each ROI (mean ± standard error). by Miguel Ulla (384576)

Significant decrease in serum liver enzymes level (AST and ALT) was detected in the IL-1α or IL-1β deficient mice compared to WT mice after FHF induction. by Maya Sultan (2863391)

Prenatal stress induces global decrease of reelin expressing neurons density in the prenatal (E20) rat brain (Left side) and no changes of NeuN neurons density (Right side). by Ismael Palacios-García (697608)

Leaf extracts from <i>L</i>. <i>polystachyus</i> Rehd. decrease blood glucose from tail of experimental T2DM mice after gavage at different weeks. by Jinfei Wang (3366131)

Effect of the experimental diets on somatic variables in male mice of the three experimental models. by Clara Gabás-Rivera (613994)

Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in <i>Drosophila</i> by Michael A. Najarro (831657)

“…<i>Cyp12d1</i> is implicated by QTL mapped in both panels of DSPR RILs, is significantly upregulated in the presence of caffeine, and RNAi knockdown robustly decreases caffeine tolerance. Furthermore, copy number variation at <i>Cyp12d1</i> is strongly associated with phenotype in the DSPR, with a trend in the same direction observed in the DGRP (<i>Drosophila</i> Genetic Reference Panel). …”

Effect of squalene on hepatic gene expression in male wild-type mice. by Clara Gabás-Rivera (613994)

Overtrained mice show reduced signaling capacity of DLS mGluR1/5 in response to a change in the prevailing A–O contingency. by Vincent Paget-Blanc (21807763)

Estimated decrease in brood production exhibited by <i>Bombus terrestris</i> colonies during pulsed exposure to realistic imidacloprid residues, equivalent to those previously dete... by Ian Laycock (479653)

“…</p>a<p>Refers to the estimated decrease in brood production expected after a 14-day exposure to imidacloprid at the given dosage.…”

Effect of dietary squalene supplementation on plasma parameters in male wild-type mice. by Clara Gabás-Rivera (613994)

Effect of dietary squalene supplementation on plasma parameters in male <i>Apoa1</i>-deficient mice. by Clara Gabás-Rivera (613994)

Region similarity and individual similarity across the three age groups: a) young (<30 years, b) middle-aged (≥30 & <60 years), and c) old age (≥60 years) for all cognitive systems... by Andrew Patton (10224161)

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Cortical morphology of the femur at mid diaphysis (adjusted for bone mass), bone volume fraction (BV/TV) (adjusted for body mass), and trabecular microarchitecture of the distal fe... by Daksh Arora (16510065)

Cardiac adherent proliferating cells increase T regulatory cells, increase apoptotic CD4 and CD8 T cells, and decrease apoptotic T regulatory cells in Coxsackievirus B3-infected mi... by Kapka Miteva (192634)

Onset of nilotinib resistance in K562 and K562-Dox cells coincides with ABCB1 overexpression; ABCB1 levels decrease upon continued high dose nilotinib exposure. by Laura N. Eadie (3044079)

Native A1AT effect on CS-exposed AM phagocytosis and global scavenging function following concomitant Fc-coated and apoptotic targets exposure. by Karina A. Serban (553981)

<i>P</i>. <i>aeruginosa</i> biofilm formation is decreased by reducing potassium efflux from airway epithelial cells through inhibition of BK_Ca channels. by Glenn J. Rapsinski (6619841)

Gliding motility of the size-modified HMW2-derivative mutants. by Daisuke Nakane (833480)