Supplementary Material for: Characteristics and Healthcare Costs in the Aging Hepatitis B Population of Japan: A Nationwide Real-World Analysis by Yotsuyanagi H. (10945812)

“…<b><i>Methods:</i></b> This cross-sectional study characterized the demographics, comorbidities, and healthcare costs of a large Japanese real-world adult (≥18 years) CHB patient (ICD-10: B18.1) population from the Medical Data Vision database from January 01, 2012, to December 31, 2016. …”

Table_1_Causal associations between gut microbiota and Cholestatic liver diseases: a Mendelian randomization study.XLSX by Jiaqi Yang (4380466)

“…</p>Result<p>This two-sample MR study indicated that the order Bacillales, family Peptostreptococcaceae, family Ruminococcaceae, genus Anaerotruncu was associated with a decreased risk of developing PBC, and that order Selenomonadales, family Bifidobacteriaceae may be factors that increase the risk of PBC. …”

Table_1_Microbiological profile of diabetic foot infections in China and worldwide: a 20-year systematic review.docx by Yu-dun Qu (17869511)

“…We aimed to determine the incidence and antibiotic susceptibility of DFI pathogens worldwide, focusing on Asia and China.</p>Methods<p>Through a comprehensive literature search, we identified published studies on organisms isolated from DFI wounds from January 2000 to December 2020.…”

DataSheet1_Shifts in soil phosphorus fractions during seasonal transitions in a riparian floodplain wetland.DOCX by Jacob Coppolino (14234066)

“…Seasonal flooding during spring thaw contributed to a pulse of dissolved reactive P, but temperature monitoring showed that the wetland soil did not experience freeze-thaw cycling. …”

BRAHMA ATPase of the SWI/SNF Chromatin Remodeling Complex Acts as a Positive Regulator of Gibberellin-Mediated Responses in Arabidopsis by Rafal Archacki (387712)

“…This study revealed that in <i>brm-1</i> plants, depleted in SWI/SNF BRAHMA (BRM) ATPase, a number of GA-related phenotypic traits are GA-sensitive and that the loss of BRM results in markedly decreased level of endogenous bioactive GA. …”

Table_3_Causal associations between gut microbiota and Cholestatic liver diseases: a Mendelian randomization study.XLSX by Jiaqi Yang (4380466)

“…</p>Result<p>This two-sample MR study indicated that the order Bacillales, family Peptostreptococcaceae, family Ruminococcaceae, genus Anaerotruncu was associated with a decreased risk of developing PBC, and that order Selenomonadales, family Bifidobacteriaceae may be factors that increase the risk of PBC. …”

Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink by Hilda J. I. de Jong (314601)

“…<div><p>We examined the association between statin use and the risk of rheumatoid arthritis (RA), with special focus on describing the patterns of risks of RA during statin exposure in a large population-based cohort in the United Kingdom. …”

Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity by Heather C. Whalley (287657)

“…The rarity of such variations means that their study involves small group numbers, however they are amongst the strongest known genetic risk factors for major mental illness and are likely to have large neural effects. DISC1 (Disrupted in Schizophrenia 1) is a gene containing one such risk variant, identified in a single Scottish family through its disruption by a balanced translocation of chromosomes 1 and 11; t(1;11) (q42.1;q14.3).…”

Assessment of renal function in routine care of people living with HIV on ART in a resource-limited setting in urban Zambia by Andreas Deckert (756045)

“…However, approximately 5% of PLWH on ART may have clinically relevant decreased eGFR, and 27% hypertension. While a routine renal assessment might not be feasible, strategies to identify patients at risk are warranted. …”

Table_1_Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model.XLSX by Azhaar Ashraf (6439022)

“…For example, iron to astroglia ratio showed age-related increases in the substantia nigra and globus pallidus, while the ratio was decreased in the striatum. Meanwhile, copper and zinc to astroglia ratios showed a similar regional decline. …”

Supplementary Material for: Metabolic Effects of Growth Hormone Treatment in Short Prepubertal Children: A Double-Blinded Randomized Clinical Trial by Tidblad A. (10269506)

“…<b><i>Introduction:</i></b> Growth hormone (GH) is a central hormone for regulating linear growth during childhood and also highly involved in the metabolism of lipids, carbohydrates, and protein. …”

Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment by Adam A. Friedman (812702)

“…We describe the results of a combination screen of an unprecedented scale in mammalian cells performed using a collection of targeted, clinically tractable agents across a large panel of melanoma cell lines. …”

Data_Sheet_1_Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study.ZIP by Hao Qin (113159)

“…The IVW-MR also found a suggestive evidence that decreased LDL-C levels mediated by the PCSK9 (proprotein convertase subtilisin-kexin type 9) gene were associated with a reduced risk of any stroke (AS) (OR, 1.31; 95% CI, 1.13–1.52; p = 0.0003), any ischemic stroke (AIS) (OR, 1.29; 95% CI, 1.10–1.51; p = 0.001), and LAS (OR, 1.73; 95% CI, 1.15–2.59; p = 0.008), while NPC1L1 (Niemann-Pick C1-like protein)-mediated LDL-C levels were associated with a higher risk of small vessel stroke (SVS) (OR, 6.10; 95% CI, 2.13–17.43; p = 0.0008). …”

Table1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.xlsx by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

Datasheet1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.pdf by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

DataSheet_1_Cascading effects of seed-stem-individual spatial patterns along a grazing gradient.docx by Zhou Qin-Yuan (14792533)

“…The results showed the following: (1) Seed size increased with increasing grazing intensity, and the coefficient of variation for seed size and seed number in the heavy grazing treatment was greater than 0.6. (2) The structural equation model showed that grazing treatment had a positive effect on seed number, seed size and reproductive stem number and a negative effect on reproductive stem weight. (3) Grazing treatment did not affect the resource allocation to reproductive stems and vegetative stems per unit length of reproductive K. humilis individuals. (4) Compared with the number of reproductive individuals in the no grazing treatment, the number in the heavy grazing treatment decreased significantly, and the negative correlation between reproductive individuals and nonreproductive individuals changed from a full-scale negative correlation to a small-scale negative correlation and a large-scale positive correlation. …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Table_2_Neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer: A new era for anal preservation.xlsx by Yaqi Wang (1555240)

“…It was demonstrated to decrease the local recurrence rate and increase the tumor response grade. …”

Table_1_Oxidative balance score: a potential tool for reducing the risk of colorectal cancer and its subsites incidences.docx by Yu Chang (392011)

“…The objective of this study was to assess the relationship between OBS and the risk of CRC, its subsites, and common complications in a large prospective cohort study.</p>Methods<p>We included data from 175,808 participants in the UK Biobank data sample repository from 2006 to 2010. …”