Semi-knockout YAP rescue heart function from valve thickening. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i>; <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> and <i>Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> hearts. …”

Table_2_SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.docx by Helene Sertznig (9649127)

“…Type I interferons (IFN-I) play a crucial role in the innate immunity against HIV-1 by inducing the expression of IFN-stimulated genes (ISGs) including potent host restriction factors. …”

Image_1_Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach.pdf by Xiaohong Cheng (275970)

“…While capacitation and the acrosome reaction, key processes before fertilization, involve substantial lipidomic alterations, a comprehensive understanding of the changes in human spermatozoa's lipidomic profiles during these processes remains unknown. …”

Image3_ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic.tif by Jennifer Streeter (19729264)

“…</p>Methods<p>We generated mice with homozygous floxed Opa1 and Atf4 alleles and a tamoxifen-inducible Cre transgene controlled by the human skeletal actin promoter to enable simultaneous depletion of OPA1 and ATF4 in skeletal muscle (mAO DKO). …”

DataSheet_1_Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells.pdf by Yingjie Xie (8459550)

“…Therefore, that the proportion of CD11b⁺Gr-1⁺ cells increased in the spleen of tumor-bearing hosts may not be villainy after treatment, when these drugs suppress the immunosuppressive ability of CD11b⁺Gr-1⁺ cells and promote it mature to replenish dendritic cell, at the same time. Generally, JHD may be a complementary and alternative drug for attenuating the immunosuppressive status induced by hepatocellular carcinoma, possibly by promoting differentiation and inhibiting the immunosuppressive activity of MDSCs.…”

Table_1_Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood–Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight... by Lin-Yan Huang (6274160)

“…Intravenous serum-derived exosome treatment may, therefore, provide a novel clinical therapeutic strategy for ischemic stroke.…”

Table2_Isoquercitrin alleviates pirarubicin-induced cardiotoxicity in vivo and in vitro by inhibiting apoptosis through Phlpp1/AKT/Bcl-2 signaling pathway.XLSX by Lei Wang (6656)

“…Isoquercitrin (IQC) is a natural flavonoid with anti-oxidant and anti-apoptosis properties. …”

Data_Sheet_1_Sexual Dimorphisms of Protein-Coding Gene Profiles in Placentas From Women With Systemic Lupus Erythematosus.PDF by Hui-hui Li (12242504)

“…The results suggest that the SLE-dysregulated protein-coding genes in placentas may contribute to the pathophysiological progress of SLE pregnancies in a fetal sex-specific manner, leading to adverse pregnancy outcomes.…”

Video_7_Additional Improvement of Respiratory Technique on Vascular Function in Hypertensive Postmenopausal Women Following Yoga or Stretching Video Classes: The YOGINI Study.MOV by Cláudia Fetter (9315074)

“…</p><p>Study Design: Hypertensive postmenopausal women were recruited and randomized for 12 weeks, twice a week, of supervised yoga or stretching video classes of 75 min for 12 weeks associated or not with respiratory technique. …”

Minimum data set used in the article. by Shizhen Xu (4474321)

“…It analyzed variation patterns of soil carbon, nitrogen, and phosphorus across different land-use types in the study area and explored the impacts of land-use types and seasonal climate fluctuations on these soil elements, aiming to provide a scientific basis for soil management. Results showed that during 2018–2019, the average organic carbon content in forestland soil (48.82 g/kg) was higher than that in grassland (38.32 g/kg) and cropland (30.80 g/kg). …”

Table_2_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.DOCX by Gwenoline Borhis (8518077)

“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4⁺ T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”

Presentation_5_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.pptx by Gwenoline Borhis (8518077)

“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4⁺ T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”

Image_1_Long Noncoding RNA X-Inactive-Specific Transcript Promotes the Secretion of Inflammatory Cytokines in LPS Stimulated Astrocyte Cell Via Sponging miR-29c-3p and Regulating N... by Mengqi Zhang (1580830)

“…</p>Results<p>XIST expression and NFAT5 protein level was increased, whereas miR-29c-3p expression was decreased in the epilepsy rat model and LPS-treated CTX-TNA2 cells. …”

DataSheet_1_Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells.pdf by Yingjie Xie (8459550)

“…Therefore, that the proportion of CD11b⁺Gr-1⁺ cells increased in the spleen of tumor-bearing hosts may not be villainy after treatment, when these drugs suppress the immunosuppressive ability of CD11b⁺Gr-1⁺ cells and promote it mature to replenish dendritic cell, at the same time. Generally, JHD may be a complementary and alternative drug for attenuating the immunosuppressive status induced by hepatocellular carcinoma, possibly by promoting differentiation and inhibiting the immunosuppressive activity of MDSCs.…”

Characteristics of the 12 included RCTs. by Jing Kang (251503)

“…</p><p>Results</p><p>Our meta-analysis included a total of 12 studies. Overall analysis indicated that ICIs plus chemotherapy could significantly improve OS (HR = 0.79; 95% CI: 0.74–0.84; <i>I</i>² = 44.4%, <i>P</i> = 0.055), PFS (HR = 0.62; 95% CI: 0.59–0.67; <i>I</i>² = 75.3%, <i>P</i> = 0.000), and ORR (RR = 1.48; 95% CI: 1.27–1.73; <i>I</i>² = 79.0%, <i>P</i> = 0.000) when compared to chemotherapy treatments. …”

Image1_Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK.tif by Ying Yang (24175)

“…L02 and Huh-7 cells were induced by sodium oleate to establish a NAFLD cell model. The effects of NAR on lipid accumulation were detected by oil red O staining. …”

Image_2_The effect of live-performed music therapy with physical contact in preterm infants on parental perceived stress and salivary cortisol levels.JPEG by Monia Vanessa Dewan (18260473)

“…Introduction<p>Parents of preterm infants face a stressful life event which might have long term impact on the parent–child relation as well as on the infant’s cognitive and socio-emotional development. …”

Presentation_1_Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive brea... by Wei Bin Fang (781225)

“…Despite standardized treatment involving lumpectomy and radiation therapy, up to 25% of patients with DCIS experience disease recurrence often with invasive ductal carcinoma (IDC), indicating that a subset of patients may be under-treated. As most DCIS cases will not progress to invasion, many patients may experience over-treatment. …”

Data Sheet 2_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…Yiqi Huoxue decoction (YQHX), a Traditional Chinese Medicine formula, shows potential for myocardial infarction (MI) prevention and treatment. …”

Table 5_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct... by Quan Sun (175631)

“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”