Image_1_Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway.tif by Mingming Zhao (760369)

“…In vitro, we detected astrocytic viability and extracellular nitric oxide by an assay kit, intracellular reactive oxygen species by a DCFH-DA probe, inflammation and apoptosis-related protein expression by immunofluorescence staining, and the astrocytic apoptosis rate by flow cytometry. …”

DataSheet1_Effect of different biochar particle sizes together with bio-organic fertilizer on rhizosphere soil microecological environment on saline–alkali land.docx by Yin-yu Gu (13116027)

“…However, soil physicochemical properties and the microbiome diversity of rhizosphere soil after the application of different-sized particles of biochar together with BOF in saline–alkali land have not been thoroughly described. A field experiment was performed to investigate the effects of different-sized particles of apple shoot biochar (60, 30, and 10 mesh) together with BOF on soil bacteria (using Illumina high-throughput sequencing) and the physicochemical properties of Mesembryanthemum cordifolium L. f. grown on saline–alkali land. …”

Table2_Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway ac... by Wilbert Bouwman (9534287)

“…Differential diagnosis remains a challenge. Anti-TNFα treatment is an important treatment for IBD, yet resistance frequently occurs and cannot be predicted. …”

Image_4_Porcine epidemic diarrhea virus strain FJzz1 infection induces type I/III IFNs production through RLRs and TLRs-mediated signaling.tif by Pengfei Chen (462170)

“…In this study, we observed that various IFN-stimulated genes (ISGs) were upregulated significantly in a time- and dose-dependent manner in LLC-PK1 cells infected with the PEDV G2 strain FJzz1. …”

Formation of Zn(II) and Cd(II) Coordination Polymers Assembled by Triazine-Based Polycarboxylate and <i>in-Situ</i>-Generated Pyridine-4-thiolate or Dipyridylsulfide Ligands: Obser... by Qilong Zhu (2048197)

“…Three novel coordination polymers, [Cd₅(HTTHA)₂(Hpt)₄(H₂O)]·4H₂O (<b>1</b>; H₆TTHA = 1,3,5-triazine-2,4,6-triamine hexaacetic acid, Hpt = pyridinium-4-thiolate), {[Cd₃(TTHA)(dps)(H₂O)₃]₂}·H₂O (<b>2</b>), and [Zn₃(TTHA)(dps)(H₂O)]·5H₂O (<b>3</b>; dps =4,4′-dipyridylsulfide), have been synthesized by the flexible hexapodal acid H₆TTHA and <i>in-situ</i>-generated Hpt and dps ligands from a 4,4′-dipyridyldisulfide (dpds) precursor through cleavage of both S–S and S–C(sp²) bonds and temperature-dependent chemical rearrangement under hydrothermal conditions. …”

N-3 Poly-Unsaturated Fatty Acids Shift Estrogen Signaling to Inhibit Human Breast Cancer Cell Growth by WenQing Cao (107805)

“…The current study showed that docosahexaenoic acid (DHA, C22:6), eicosapentaenoic acid (EPA, C20:5) shifted the pro-survival and proliferative effect of estrogen to a pro-apoptotic effect in human breast cancer (BCa) MCF-7 and T47D cells. 17 β-estradiol (E2) enhanced the inhibitory effect of n-3 PUFAs on BCa cell growth. …”

Data Sheet 1_Changes in the prevalence of hepatitis B virus and its related factors in Inner Mongolia between 2006 and 2020.doc by Xuejie Ding (6634538)

“…</p>Methods<p>The same sampling process was used in investigations conducted in 2006 and 2020. A multi-stage stratified random sampling method was used to select subjects aged 1–60 years old from 12 cities in Inner Mongolia. …”

DataSheet_1_Integrated transcriptomics and metabolomics analysis provide insight into the resistance response of rice against brown planthopper.pdf by Shaojie Shi (5546837)

“…</p>Methods<p>Here, we conducted a transcriptomic and metabolomic analysis of Bph30-transgenic (BPH30T) and BPH-susceptible Nipponbare plants to elucidate the response of Bph30 to BPH infestation.…”

Systematic review of microRNAs in human acute kidney injury by Adrianna Douvris (4113439)

“…MicroRNAs (miRNAs) are implicated in AKI pathogenesis in preclinical models, but less is known about their role in humans. We conducted a systematic review to identify dysregulated miRNAs in humans with AKI.…”

Image_1_Integrative Analysis Toward Different Glucose Tolerance-Related Gut Microbiota and Diet.TIF by Rebiya Nuli (6740093)

“…Unbalanced nutrient intake in the three groups may affect the structure and abundance of the gut microbiota, which may play a role in the occurrence and development of T2DM.…”

Table_1_Changes in the Gut Microbiome and Predicted Functional Metabolic Effects in an Australian Parkinson’s Disease Cohort.XLSX by Jade E. Kenna (7147769)

“…</p><p>Conclusion: This study provides the first comprehensive characterization of the gut microbiome and predicted functional metabolic effects in a southern hemisphere PD population, further exploring the possible mechanisms whereby the gut microbiota may exert their influence on this disease, and providing evidence for the incorporation of such data in future individualized therapeutic strategies.…”

Table_1_Unlocking potential: low frequency subthalamic nucleus stimulation enhances executive function in Parkinson’s disease patients with postural instability/gait disturbance.DO... by Guofan Qin (16903098)

“…This study was designed in a double-blinded randomized cross-over manner, aimed to verify the effect of low frequency STN-DBS on cognition of PIGD patients. …”

Data_Sheet_7_ZmPP2C26 Alternative Splicing Variants Negatively Regulate Drought Tolerance in Maize.XLSX by Fengzhong Lu (12373204)

“…In this study, we characterized a clade B member of maize PP2C family, i.e., ZmPP2C26, that negatively regulated drought tolerance by dephosphorylating ZmMAPK3 and ZmMAPK7 in maize. …”

Image 11_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Table_3_Physiological, Proteomic Analysis, and Calcium-Related Gene Expression Reveal Taxus wallichiana var. mairei Adaptability to Acid Rain Stress Under Various Calcium Levels.do... by Wen-Jun Hu (447700)

“…Studies have shown that AR can leach calcium ions from plants and soil. Calcium (Ca) is also a crucial regulator of the plant stress response, whereas there are few reports on how Ca regulates the response of AR-resistant woody plants to AR stress. …”

Table_1_Characterization and spoilage potential of Bacillus cereus isolated from farm environment and raw milk.DOCX by Lu Meng (289653)

“…This study addresses the biodiversity, toxicity, and proteolytic activity of B. cereus sl from 82 environmental samples and 18 raw bovine milk samples from a dairy farm in the region of Tianjin. In sum, 47 B. cereus sl isolates were characterized through biochemical tests, 16S rRNA gene sequencing, and panC gene analysis. …”

Data_Sheet_1_Plasmodiophora brassicae-Triggered Cell Enlargement and Loss of Cellular Integrity in Root Systems Are Mediated by Pectin Demethylation.PDF by Karolina Stefanowicz (3399638)

“…The development of these structures is a consequence of increased cell proliferation followed by massive enlargement of cells colonized with the pathogen. …”

Image 12_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Image_3_B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.tif by Christopher Tay (335988)

“…These findings suggest that targeting B cell and CD4 T cell interaction may be a therapeutic strategy to limit atherosclerosis progression.…”

Data_Sheet_7_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP by Zhi Liu (165121)

“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”