Data Sheet 1_Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19.pdf by Xin Pan (3712768)

“…Among the biomarkers indicative of macrophage polarization, compared to non-ARDS patients, a significant increase in IL-10, Inducible nitric oxide synthase (iNOS), and Arginase-1 (Arg-1) were observed in ARDS patients, while Tumor necrosis factor-α (TNF-α) was decreased. …”

Table_9_Antioxidant Activity and the Potential Mechanism of the Fruit From Ailanthus altissima Swingle.XLSX by Ya-nan Mo (11829002)

“…<p>The fruits of Ailanthus altissima Swingle (AS) possess a variety of pharmacological activities. Its antioxidant activity and the potential mode of action have not yet been investigated. …”

Image_4_Probiotic Lactobacillus rhamnosus GG Promotes Mouse Gut Microbiota Diversity and T Cell Differentiation.TIF by Chun-wei Shi (9856922)

“…Furthermore, LGG could effectively increase the expression of Th1-type cytokines (IFN-γ) and Th2 cytokines (IL-4) in CD4⁺ T cells, indicating that the proportion of Th1 and Th2 cells in mice with LGG treatment was in a high equilibrium state compared to the control group. …”

Table1_Immune-Related Molecular Profiling of Thymoma With Myasthenia Gravis.DOC by Jinman Zhuang (11584516)

“…Our aim was to investigate immune-related lncRNA profiles of a set of candidate genes for better understanding of the molecular mechanism underlying the pathogenesis of thymoma with or without MG.…”

Ononin chemical structure. by Fang Xu (138747)

“…</p><p>Conclusion</p><p>Our results demonstrated that ononin may ameliorate cartilage damage and inflammatory response in OA rats by downgrading MAPK and NF-κB pathways, thus identifying ononin as a potential novel drug to treat OA.</p></div>…”

Table_1_Effect of interval time between hysterosalpingography and intrauterine insemination on the pregnancy outcome of infertile patients.xlsx by Li Ling (424480)

“…The generalized estimating equation with Poisson distribution was used to estimate the risk ratios (RRs) and 95% confidence intervals (CIs) of different groups.</p>Results<p>A total of 413 patients completed 701 IUI cycles during the study period, <6months interval group, 415 cycles; 6-12 months interval group, 138 cycles; >12 months interval group, 148 cycles. …”

DataSheet4_Salvia chinensia Benth induces autophagy in esophageal cancer cells via AMPK/ULK1 signaling pathway.ZIP by Lei Jia (303610)

“…<p>Salvia chinensia Benth (Shijianchuan in Chinese, SJC) has been used as a traditional anti-cancer herb. SJC showed good anti-esophageal cancer efficacy based on our clinical application. …”

Image_3_Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI.jpg by Neftali Ramirez (13251924)

“…In steady state, naïve B cells had increased cell death pathways and reduced cell metabolism pathways, while after stimulation, enhanced immune responses and decreased cell survival were detected. Using a multi-omics approach, our findings provide valuable insights into the impaired biology of naïve B cells from TACI mutation carriers.…”

Data_Sheet_1_Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice.PDF by Stefan Washausen (11424019)

“…We demonstrate that each of the three paired epibranchial placodes is regulated by a unique combination of FGF and/or bone morphogenetic protein (BMP) signaling. …”

Data Sheet 1_Evaluation of tolerability and safety of transcranial electrical stimulation with gel particle electrodes in healthy subjects.pdf by Chuangchuang Chang (20179632)

“…</p>Objective<p>Our study utilized a specially designed and validated transcranial electrical stimulation stimulator along with preconfigured gel particle electrodes placed at F3 and F4 in the prefrontal lobes. …”

Image_2_Intermittent Fasting Reshapes the Gut Microbiota and Metabolome and Reduces Weight Gain More Effectively Than Melatonin in Mice.tif by Jingliang Liu (1870555)

“…</p><p>Objective: This study aimed to investigate the effects of IF on body fat and the gut microbiota and metabolome as well as a potential interaction with melatonin.</p><p>Methods: Male C57BL/6J mice (23.0 ± 0.9 g, 6 wk old) were randomly assigned into four groups (12 mice/group): control (C), intermittent fasting (F), melatonin (M), and intermittent fasting plus melatonin (MF). …”

DataSheet_1_Chinese medicine PaBing-II protects human iPSC-derived dopaminergic neurons from oxidative stress.docx by Shouhai Wu (2252833)

“…Background<p>PaBing-II Formula (PB-II) is a traditional Chinese medicine for treating Parkinson’s disease (PD). …”

Image_5_Intermittent Fasting Reshapes the Gut Microbiota and Metabolome and Reduces Weight Gain More Effectively Than Melatonin in Mice.tif by Jingliang Liu (1870555)

“…</p><p>Objective: This study aimed to investigate the effects of IF on body fat and the gut microbiota and metabolome as well as a potential interaction with melatonin.</p><p>Methods: Male C57BL/6J mice (23.0 ± 0.9 g, 6 wk old) were randomly assigned into four groups (12 mice/group): control (C), intermittent fasting (F), melatonin (M), and intermittent fasting plus melatonin (MF). …”

Table_1_Long-term menopause exacerbates vaginal wall support injury in ovariectomized rats by regulating amino acid synthesis and glycerophospholipid metabolism.xlsx by Xia Yu (486142)

“…Purpose<p>Menopause is a risk factor for pelvic organ prolapse (POP) and is frequently associated with diminished vaginal wall support. …”

Clinical Determinants of HIV-1B Between-Host Evolution and their Association with Drug Resistance in Pediatric Patients by Israel Pagán (52437)

“…Using this data, we have also constructed a simple multivariate model explaining between 55% and 66% of the variance in HIV-1B evolutionary parameters in pediatric populations. …”

Dexmedetomidine Acts via the JAK2/STAT3 Pathway to Attenuate Isoflurane-Induced Neurocognitive Deficits in Senile Mice by Yanna Si (3234477)

“…Cognitive function was assessed 19 days later using a 5-day testing regimen with Morris water maze. …”

Image_2_Global, regional, and national years lived with disability due to blindness and vision loss from 1990 to 2019: Findings from the Global Burden of Disease Study 2019.TIF by Shasha Li (139491)

“…Purpose<p>This study aimed to provide a comprehensive assessment of burden estimates and the secular trend of blindness and vision loss, as measured by years lived with disability (YLDs), at the global, regional, and national levels.…”

image1_Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.tif by Jiaji Hu (9997754)

“…<p>Acute liver injury is a rapidly deteriorating clinical condition with markedly high morbidity and mortality. …”

Video_6_Advanced Microscopy Reveals Complex Developmental and Subcellular Localization Patterns of ANNEXIN 1 in Arabidopsis.avi by Michaela Tichá (9207320)

“…Massive relocation and accumulation of ANN1-GFP at the PM and in Hechtian strands and reticulum in plasmolyzed cells suggest a possible osmoprotective role of ANN1-GFP during plasmolysis/deplasmolysis cycle. …”

Table_2_Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19.xlsx by Lowell Ling (8433594)

“…The secondary objective was to assess the associations between cytokines and clinical endpoints in critically ill patients. A total of 40 adult patients (mild = 8, moderate = 15, severe/critical = 17) hospitalized with COVID-19 were included in this study. …”