Data_Sheet_3_Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells.xlsx by Souvarish Sarkar (8382513)

“…We validated progranulin (PGRN) as a lysosomal PD-associated protein that is downregulated by αSyn_Agg in microglia in-vivo and is expressed by microglia in post-mortem PD brain, congruent with our in vitro findings.…”

Table8_α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis.XLSX by Tian-Tian Jiang (11857058)

“…<p>A previously validated anti-rheumatic compound α-mangostin (MAN) shows significant metabolism regulatory effects. …”

Data_Sheet_1_Mayaro Virus Replication Restriction and Induction of Muscular Inflammation in Mice Are Dependent on Age, Type-I Interferon Response, and Adaptive Immunity.PDF by Camila Menezes Figueiredo (7446725)

“…Similar to Chikungunya (CHIKV) and other arthritogenic Alphavirus, MAYV-induced disease shows a high prevalence of persistent arthralgia, and myalgia. …”

The GABBR1/miR-19b-3p/WNT2B axis regulates insulin resistance and liver injury in diabetes with viral infection: mechanistic and therapeutic insights by Rui Yang (293531)

“…This pathway represents a potential therapeutic target for mitigating the comorbidity of diabetes and viral infection.…”

Genes Responsive to Elevated CO₂ Concentrations in Triploid White Poplar and Integrated Gene Network Analysis by Juanjuan Liu (384099)

“…While the effects of elevated CO₂ on plant growth, physiology and metabolism have been studied, there is now a pressing need to understand the molecular mechanisms of how plants will respond to future increases in CO₂ concentration using genomic techniques.…”

Image_1_Alterations in the Mineral Bone Metabolism of Living Kidney Donors After Uni-Nephrectomy: Prospective Observational Study.JPEG by Hanbi Lee (11504314)

“…Moreover, all of these factors were independently associated with high ΔFEPi upon multivariable logistic regression analysis. LKDs showed a significant change in mineral bone metabolism after uni-nephrectomy, especially when the donors had preexisting HTN, lower baseline FEPi, and showed greater loss of kidney function. …”

Table1_Characteristics of Precipitation During Meiyu and Huang-Huai Rainy Seasons in Anhui Province of China.DOCX by Yuliang Zhou (11518327)

“…For the first Meiyu period during 1957–2020, the average onset and ending dates are 14th June and 10th July, respectively, while the corresponding precipitation presents a decreasing tendency from south to north regions in Anhui Province. …”

Table1_Comprehensive analysis of m7G modification patterns based on potential m7G regulators and tumor microenvironment infiltration characterization in lung adenocarcinoma.XLSX by Shouzheng Ma (12264398)

“…Nonetheless, the potential regulatory role of N7-methylguanosine (m⁷G) modification in shaping and impacting the TME remains unclear.</p><p>Methods: A comprehensive analysis was performed to explore the m⁷G modification patterns based on 24 potential m⁷G regulators in 817 lung adenocarcinoma (LUAD) patients, and the TME landscape in distinct m⁷G modification patterns were evaluated. …”

Image_1_Suppression of weed and insect populations by living cover crop mulches in organic squash production.jpg by Dylan Bruce (13913982)

“…Living mulches of Dutch white clover (Trifolium repens), annual ryegrass (Lolium multiflorum), and a mix of Dutch white clover and annual ryegrass were compared with full tillage cultivated ground and straw mulch controls for effect on yield, fruit marketability, weed and pest counts, and weed management time. …”

Image_1_Simian Varicella Virus DNA in Saliva and Buccal Cells After Experimental Acute Infection in Rhesus Macaques.tif by Vicki Traina-Dorge (6683420)

“…To develop non-invasive methods of assessing SVV infection, we tested for the presence of SVV DNA in saliva, as has been documented in human VZV infection, and in buccal cells to determine whether epithelial cells might provide a more reliable source of material for analysis. …”

Knowledge of congenital cytomegalovirus (cCMV) among physical and occupational therapists in the United States by Kathleen M. Muldoon (247404)

“…Our study identified both a low level of therapist awareness and poor demonstrated understanding of cCMV. …”

Image_2_Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis.TIF by Bartosz Pilecki (3091188)

“…Here, we investigated the role of SP-D in a murine model of CS-induced inflammation. Pulmonary SP-D localization and abundance was compared between smoker and non-smoker individuals. …”

Image_1_Exopolysaccharide-producing bacteria enhanced Pb immobilization and influenced the microbiome composition in rhizosphere soil of pakchoi (Brassica chinensis L.).pdf by Ruiwen Cao (5507192)

“…The potential of Pseudoalteromonas agarivorans Hao 2018, a high EPS-producing marine bacterium, to produce EPS in soil filtrate, immobilize Pb, and inhibit its uptake by pakchoi (Brassica chinensis L.) was studied in this work. …”

Image_2_Alteration of Intestinal Microbiota Composition in Oral Sensitized C3H/HeJ Mice Is Associated With Changes in Dendritic Cells and T Cells in Mesenteric Lymph Nodes.jpg by Cui Zhou (1388874)

“…The intestinal bacterial community structure was analyzed, followed by Spearman correlation analysis between changed gut microbiota species and allergic parameters. Sensitization induced a noticeable allergic response to the gavage of OVA without adjuvant. …”

Data_Sheet_1_Single-cell transcriptome revealed dysregulated RNA-binding protein expression patterns and functions in human ankylosing spondylitis.ZIP by Zheng Ren (1766506)

“…</p>Results<p>(1) Compared with the HC group, the numbers of B, DC (dendritic cells), CD14⁺ Mono and CD8⁺ T cells were increased in AS group, while the numbers of platelet (platelets), CD8⁺ NKT, CD16⁺ Mono (non-classical monocytes), Native CD4⁺ T and NK were decreased. (2) Through the analysis of RBP genes in B cells, some RBPs were found to play an important role in B cell differentiation and function, such as DDX3X, SFPQ, SRRM1, UPF2. (3) It may be related to B-cell receptor, IgA immunity, NOD-like receptor and other signaling pathways; Through the analysis of RBP genes in CD8⁺ T cells, some RBPs that play an important role in the immune regulation of CD8⁺ T were found, such as EIF2S3, EIF4B, HSPA5, MSL3, PABPC1 and SRSF7; It may be related to T cell receptor, TNF, IL17 and other signaling pathways. (4) Based on bulk RNA-seq, it was found that compared with HC and AS patients, differentially expressed variable splicing genes (RASGs) may play an important role in the occurrence and development of AS by participating in transcriptional regulation, protein phosphorylation and ubiquitination, DNA replication, angiogenesis, intracellular signal transduction and other related pathways.…”

Data_Sheet_1_Antenatal Endotoxin Impairs Lung Mechanics and Increases Sensitivity to Ventilator-Induced Lung Injury in Newborn Rat Pups.pdf by Erica W. Mandell (9979040)

“…We speculate that antenatal inflammation primes the lung for a more marked VILI response, suggesting an adverse synergistic effect of antenatal and postnatal exposures.…”

Image1_Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression.JPEG by Laetitia L. Lecante (12716315)

“…Here, we took advantage of a transgenic rat expressing the green fluorescent protein specifically in germ cells allowing purification of perinatal GFP-positive germ cells. …”

MyD88-dependent inflammasome activation and autophagy inhibition contributes to <i>Ehrlichia</i>-induced liver injury and toxic shock by Muhamuda Kader (437247)

“…<div><p>Severe hepatic inflammation is a common cause of acute liver injury following systemic infection with <i>Ehrlichia</i>, obligate Gram-negative intracellular bacteria that lack lipopolysaccharide (LPS). …”

Vitexin attenuates lipopolysaccharide-induced acute lung injury by controlling the Nrf2 pathway by Ying Lu (66401)

“…<div><p>Background</p><p>A major feature of acute lung injury (ALI) is excessive inflammation in the lung. …”

Table_1_Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19.xlsx by Lowell Ling (8433594)

“…The secondary objective was to assess the associations between cytokines and clinical endpoints in critically ill patients. A total of 40 adult patients (mild = 8, moderate = 15, severe/critical = 17) hospitalized with COVID-19 were included in this study. …”