HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model by Thaiz F. Borin (4107397)

“…The ability of tumor cells to modulate TME and to escape immune-mediated attack by releasing immunosuppressive cytokines has become a hallmark of breast cancer. Our study shows the effect of IV formulation of HET0016 (HPßCD-HET0016) a selective inhibitor of 20-HETE synthesis, administered intravenously in immune-competent in vivo mouse model of murine breast cancer. 4T1 luciferase positive cells were implanted to the mammary fat pad in Balb/c mice. …”

Comparison between SE_HP and CSE_HP|SAP,R. by Alberto Porta (223657)

Interaction of TiO₂-NPs with consortium: Schematic representation of a cascade of interactions between bacterial cells and energy (hʋ) activated TiO₂-NPs and... by Ankita Mathur (781133)

Cerezyme treatment decreases fungal GlcCer in mouse models of <i>Cn</i> infection. by Ryan Rhome (232430)

Downregulation of MRP1 decreased MDR1 expression in MC3/5FU cells. by Bolei Cai (450659)

MT1-MMP gene silencing in both HUVECs and fibroblasts decreases endothelial sprout formation. by Pedro Correa de Sampaio (184186)

“…B – Quantification of endothelial cell sprouting showing a decrease in sprout formation with HUVECs expressing MT1-MMP shRNAs. …”

Restricting cell size decreases [Ca²⁺]_i frequency. by Charles Godbout (540424)

Elimination of GLUT1 expression in G1fPt cells decreases tumor growth. by Christian D. Young (211228)

GD3 synthase overexpression decreases subcutaneous tumor growth of Hep3B cells. by Josep M. Lluis (256726)

Loss of <i>Nf1</i> decreases sleep and increases metabolic rate in the SAMM system. by Elizabeth B. Brown (4582978)

“…<p>Sleep duration and metabolic rate were measured in the SAMM system. <b>A</b>. There is a significant effect of genotype on sleep duration (two-way ANOVA: F_2,154 = 10.92, <i>P</i><0.0001). …”

Liver steatosis and dyslipidemia after HCV eradication by direct acting antiviral agents are synergistic risks of atherosclerosis by Naoki Kawagishi (6111821)

“…The association between changes in liver steatosis, lipid-metabolism, and genetic and clinical factors was analyzed.</p><p>Results</p><p>A total of 117 patients were included. The mean CAP and low-density lipoprotein cholesterol (LDL-C) levels were significantly elevated at SVR24. …”

NEDD4 knockout decreases IFITM3 ubiquitination and protects cells from virus infection. by Nicholas M. Chesarino (781971)

RBC ROS production induces Band 3 phosphorylation, decreasing membrane deformability and lipid mobility. by Joseph Khoory (844565)

“…<p>(A) GPA mediated ROS production increases band 3 phosphorylation. …”

KSHV K1 mutant infected cells exhibit decreased survival following nutrient deprivation. by Penny M. Anders (3338136)

Decreasing the Burden of Type 2 Diabetes in South Africa: The Impact of Taxing Sugar-Sweetened Beverages by Mercy Manyema (618205)

<i>cel1Δ</i> shows decreased virulence in two different models of cryptococcosis. by Corinna Probst (1538371)

Antagonism of miR-21 reversed EMT phenotype, as well as decreased cell migration and invasion. by Mingli Han (318317)

“…<p>MDA-MB-231 cells were transfected with hsa-miR-21 antagomir or hsa-miR-21 antagomir control at a final concentration of 50 nmol for 48 h. (A) MDA-MB-231 cells were treated with hsa-miR-21 antagomir decreased the expression of miR-21, as compared to control groups (n1 = n2 = 3; p = 0.0015), by real-time RT-PCR analysis. …”

The density of the Som+ cells in the EPL of the OB is significantly decreased in the Sp8 conditional mutant mice. by Xuhua Jiang (436379)

Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells by Einav Yehuda-Shnaidman (461266)

“…<div><p>Obesity is a key risk factor for the development of colon cancer; however, the endocrine/paracrine/metabolic networks mediating this connection are poorly understood. …”

Inhibiting SLIT-ROBO signalling decreases apoptosis as measured by an activated caspase-3/7 assay. by Rachel E. Dickinson (338692)