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27781
Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized hum...
Published 2022“…Under higher dose CEES (0.9 mM) exposure, protein and mRNA levels of PPARγ coactivator-1ɑ (PGC-1ɑ), a well-known transcription factor that regulates fatty acid oxidation, were decreased. …”
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27782
Image2_TMEM16A Plays an Insignificant Role in Myocardium Remodeling but May Promote Angiogenesis of Heart During Pressure-overload.JPEG
Published 2022“…Promotion of migration and angiogenesis by VEGF was decreased in TMEM16A low-expressed ECs but was increased in TMEM16A over-expressed ECs. …”
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27783
Image1_TMEM16A Plays an Insignificant Role in Myocardium Remodeling but May Promote Angiogenesis of Heart During Pressure-overload.JPEG
Published 2022“…Promotion of migration and angiogenesis by VEGF was decreased in TMEM16A low-expressed ECs but was increased in TMEM16A over-expressed ECs. …”
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27784
data_sheet_1_High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+–Calmodulin-Dependent Protein Kin...
Published 2018“…Therefore, in this study, we examined the global gene expression patterns depending on different frequencies of repetitive magnetic stimulation (rMS) in both undifferentiated and differentiated Neuro-2a cells to generate a comprehensive view of the biological mechanisms. …”
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27785
DataSheet1_TMEM16A Plays an Insignificant Role in Myocardium Remodeling but May Promote Angiogenesis of Heart During Pressure-overload.docx
Published 2022“…Promotion of migration and angiogenesis by VEGF was decreased in TMEM16A low-expressed ECs but was increased in TMEM16A over-expressed ECs. …”
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27786
data_sheet_2_High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+–Calmodulin-Dependent Protein Kin...
Published 2018“…Therefore, in this study, we examined the global gene expression patterns depending on different frequencies of repetitive magnetic stimulation (rMS) in both undifferentiated and differentiated Neuro-2a cells to generate a comprehensive view of the biological mechanisms. …”
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27787
Mk2/3-dependent regulation of Khsrp and <i>Cdkn1a</i><sup><i>p21</i></sup>.
Published 2015“…<b>(C)</b> Despite a typical arrest in G<sub><b>2</b></sub> upon etoposide treatment, <b>(D)</b><i>Mk2</i><sup><b><i>-/-</i></b></sup><i>;Mk3</i><sup><b><i>-/-</i></b></sup> MEFs show a decreased G<sub><b>1</b></sub> population in comparison to wt cells. …”
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27788
Numerical data for Fig 4A, 4B, 4C, 4D and 4E.
Published 2023“…Together, these studies identify a promising therapeutic strategy for CRPC and suggest that these two major epigenetic regulators buffer prostate cancers from a lethal response to cellular stresses, thereby conferring a tractable therapeutic vulnerability.…”
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27789
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27790
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27791
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27792
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27793
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27794
Numerical data for Fig 2A, 2B, 2C, 2D and 2G.
Published 2023“…Together, these studies identify a promising therapeutic strategy for CRPC and suggest that these two major epigenetic regulators buffer prostate cancers from a lethal response to cellular stresses, thereby conferring a tractable therapeutic vulnerability.…”
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27795
DataSheet1_EPM2A acts as a protective factor in prostate cancer, evidence from a real-world patient cohort.docx
Published 2022“…The results showed decreased expression of EPM2A in 95.65% of tumor tissues and was related to their prognosis, especially PCA (p = 0.008, HR = 0.57, 95% CI: 0.371–0.863). …”
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27796
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27797
Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth
Published 2019“…Interestingly, ZRANB1 is phosphorylated at Thr35, and Ser209 residues by CSNK1A1, and this phosphorylation activates its deubiquitinating activity. …”
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27798
Aβ-induced BACE1 mRNA and protein expressions in activated N2a Swe cells and their reductions by taxifolin and cilostazol.
Published 2016“…Significant decreases in BACE1 protein expression by taxifolin (50 or 100 μM), cilostazol (30 μM), and by 30 μM quercetin (a flavonoid) after 24 hr of treatment. …”
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27799
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27800
Image2_Ghrelin enhances tubular magnesium absorption in the kidney.TIF
Published 2024“…As GHSR initiates downstream signaling via protein kinase A (PKA), we found that the PKA inhibitor H89 abrogated TRPM6/7 stimulation by Ghrelin. …”