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28341
Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against <i>Vibrio cholerae</i> O1 infection among household contacts of...
Published 2018“…</p><p>Principle findings</p><p>The presence of OSP-specific plasma IgA, IgM, and IgG antibody responses on study entry were associated with a decrease in the risk of infection in household contacts (IgA, p = 0.015; IgM, p = 0.01, and IgG, p = 0.024). …”
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28342
Data_Sheet_1_Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease.docx
Published 2022“…In older 3xTgAD mice, we observed a number of sarcopenia-related phenotypes, including significantly fragmented and denervated neuromuscular junctions (NMJs) associated with a 17% reduction in sciatic nerve induced vs. direct muscle stimulation induced contractile force production, and a 30% decrease in gastrocnemius muscle mass. …”
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28343
Table1_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.DOCX
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28344
Inhibition of the histone demethylase KDM4B leads to activation of KDM1A, attenuates bacterial-induced pro-inflammatory cytokine release, and reduces osteoclastogenesis
Published 2018“…In addition, fluorescence-stained macrophages exhibited a significant decrease in global monomethyl histone 3 lysine 4 (H3K4me) levels following an Aa-LPS challenge that was prevented by KDM4B inhibition, suggesting this effect is produced through KDM1A-mediated demethylation of H3K4. …”
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28345
Image5_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28346
Data_Sheet_1_Gut Microbiota Composition Associated With Clostridium difficile-Positive Diarrhea and C. difficile Type in ICU Patients.docx
Published 2020“…CDpD might relate to a decrease in beneficial taxa (i.e., Saccharomycetes and Clostridia) and an increase in harmful taxa (e.g., Deferribacteres, Cryptomycota, Acetothermia) in gut microbiota of ICU patients. …”
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28347
Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif
Published 2020“…The major direct action target of GT is the plastoquinone Q<sub>B</sub>-site of the D1 protein in PSII, where GT inserts in the Q<sub>B</sub> binding niche by replacing native plastoquinone (PQ) and then interrupts electron flow beyond plastoquinone Q<sub>A</sub>. This leads to severe inactivation of PSII RCs and a significant decrease of PSII overall photosynthetic activity. …”
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28348
Image_1_Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus.tif
Published 2020“…The major direct action target of GT is the plastoquinone Q<sub>B</sub>-site of the D1 protein in PSII, where GT inserts in the Q<sub>B</sub> binding niche by replacing native plastoquinone (PQ) and then interrupts electron flow beyond plastoquinone Q<sub>A</sub>. This leads to severe inactivation of PSII RCs and a significant decrease of PSII overall photosynthetic activity. …”
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28349
Image3_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28350
Image1_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28351
Table2_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.XLSX
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28352
Image4_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28353
Image2_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28354
Image6_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.TIF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28355
Table3_Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment.PDF
Published 2022“…Here, we discovered that Platycodon grandiflorum (PG), a medicine and food homology herb, reduced the expression of PD-1 on the surface of CD8<sup>+</sup> T cells to exert antitumor effects in non-small cell lung cancer (NSCLC). …”
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28356
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