DataSheet_1_Integrative analysis of mitochondrial metabolic reprogramming in early-stage colon and liver cancer.pdf by Yeongmin Kim (4438870)

“…Using a genome-scale metabolic model, we demonstrated that HMGCS2 suppression increased glycolysis, lipid biosynthesis, and elongation while decreasing fatty acid oxidation in colon cancer cells. …”

Presentation_1_The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice.pdf by Rahul Pandey (195262)

“…We overexpressed CLEC16A in YTS natural killer (NK) cells and observed reduced NK cell cytotoxicity and IFN-γ release, delayed dendritic cell (DC) maturation, decreased conjugate formation, cell-surface receptor downregulation and increased autophagy. …”

Table_1_METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer.docx by Han-guang Ruan (11865917)

“…We found that the m⁶A methylated RNA was dramatically decreased in TNBC tissues and cell lines. …”

Endothelial Cells Can Regulate Smooth Muscle Cells in Contractile Phenotype through the miR-206/ARF6&NCX1/Exosome Axis by Xiao Lin (20892)

“…Furthermore, a reduction of the miR-26a-containing exosomes secreted from HUVECs affects the SMC phenotype. …”

DataSheet_1_METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer.docx by Han-guang Ruan (11865917)

“…We found that the m⁶A methylated RNA was dramatically decreased in TNBC tissues and cell lines. …”

Visualization of H2A.Z and H4K20me1’s gene-wise positive association and nucleosome-wise negative association. by Weizhong Chen (561586)

“…<p>(<b>a</b>) Nucleosome and H4K20me1/H2A.Z profiles around -2000 ~ +2000 bp of the TSS regions. …”

The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not by Yusuke K. Kawai (464561)

“…Correlations between UGT gene count and ecological factors suggested that the number of UGT1E genes is decreasing in carnivorous species. Estimates of selection pressure also support the hypothesis that diet influenced avian UGT1E gene evolution, similar to mammalian UGT1A and UGT2B genes.…”

Table_1_SLC38A10 Transporter Plays a Role in Cell Survival Under Oxidative Stress and Glutamate Toxicity.DOCX by Rekha Tripathi (9092534)

“…In this study, we have investigated the role of SLC38A10 under acute oxidative and glutamate stress in mouse primary cortical cells from SLC38A10 knockout (KO) mice. …”

Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions by Masako Tanaka (560084)

“…Hsc70 interacted with Rab1A in a chaperone-dependent manner. In addition, Hsc70 knockdown decreased the level of Rab1A and increased the level of its ubiquitination under stress conditions, suggesting that Hsc70 prevented the degradation of Rab1A denatured by stress exposure. …”

Image_7_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Image_6_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Image_2_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Data_Sheet_1_The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue.PDF by Katharina Kern (5804552)

“…Fittingly neutrophil efferocytosis was decreased in G2A-deficient mice and several lipids, which are released by neutrophils and promote G2A-mediated chemotaxis, were increased in the inflamed tissue. …”

DataSheet_2_IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer.docx by Nicholas R. Hum (12563075)

“…Furthermore, transcriptional profiles of tumor infiltrated T cells in DOX responsive tumors revealed decreased exhaustion, increased chemokine/cytokine expression, and increased activation and cytotoxic activity. γδ T cell derived IL-17A was identified to be highly abundant in the sensitive tumor microenvironment. …”

Image_3_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

Continuous glucose monitor use with and without remote monitoring in pregnant women with type 1 diabetes: A pilot study by Sarit Polsky (8721450)

“…</p><p>Results</p><p>HbA1c decreased in all groups throughout pregnancy and was significantly lower over time in women using CGM Share (n = 15) compared to CGM Alone (n = 13) or no CGM (n = 8) (p = 0.0042). …”

Image_5_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”

DataSheet_1_S100A9 Activates the Immunosuppressive Switch Through the PI3K/Akt Pathway to Maintain the Immune Suppression Function of Testicular Macrophages.docx by Zun Pan Fan (11605789)

“…Treatment with S100A9 and PI3K inhibitor decreased the proportion of M2-type TMs in control and UPEC-infected mouse. …”

DataSheet_1_Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β.pdf by Jin-Hee Park (732531)

“…Introduction<p>Lomerizine is a calcium channel blocker that crosses the blood–brain barrier and is used clinically in the treatment of migraines. …”

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity by Brandon L. Probst (727964)

“…Here, we characterized the in vitro antioxidant, anti-inflammatory, and anticancer activities of RTA 408, a novel AIM that is currently being evaluated in patients with advanced malignancies. …”