A) HSC were cultured for 24h presence or absence of IL-22 (25 ng/ml) and protein lysates were analyzed for Collagen I and III protein expression by western blots. Graph show the fold decrease of signals of a representative experiment out of 3.... by Fernanda Scopelliti (21453704)

“…Graph show the fold decrease of signals of a representative experiment out of 3. …”

Blockade of NF-κB p65 or MAPK p38 was shown to decrease EL levels in HUVECs by western blotting. by Xiaoli Zhang (135098)

The model depicting the proteomic effects of DIO1 restoration in renal cancer. by Piotr Popławski (3171912)

Combined treatment of 2-DG and radiation leads to the restoration of CD4 cells in the peripheral blood, besides decrease in the B cells. by Abdullah Farooque (632787)

Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment by Adam A. Friedman (812702)

“…We describe the results of a combination screen of an unprecedented scale in mammalian cells performed using a collection of targeted, clinically tractable agents across a large panel of melanoma cell lines. …”

Data_Sheet_1_Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study.ZIP by Hao Qin (113159)

“…The IVW-MR also found a suggestive evidence that decreased LDL-C levels mediated by the PCSK9 (proprotein convertase subtilisin-kexin type 9) gene were associated with a reduced risk of any stroke (AS) (OR, 1.31; 95% CI, 1.13–1.52; p = 0.0003), any ischemic stroke (AIS) (OR, 1.29; 95% CI, 1.10–1.51; p = 0.001), and LAS (OR, 1.73; 95% CI, 1.15–2.59; p = 0.008), while NPC1L1 (Niemann-Pick C1-like protein)-mediated LDL-C levels were associated with a higher risk of small vessel stroke (SVS) (OR, 6.10; 95% CI, 2.13–17.43; p = 0.0008). …”

Table1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.xlsx by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

Datasheet1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.pdf by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

DataSheet_1_Cascading effects of seed-stem-individual spatial patterns along a grazing gradient.docx by Zhou Qin-Yuan (14792533)

“…The results showed the following: (1) Seed size increased with increasing grazing intensity, and the coefficient of variation for seed size and seed number in the heavy grazing treatment was greater than 0.6. (2) The structural equation model showed that grazing treatment had a positive effect on seed number, seed size and reproductive stem number and a negative effect on reproductive stem weight. (3) Grazing treatment did not affect the resource allocation to reproductive stems and vegetative stems per unit length of reproductive K. humilis individuals. (4) Compared with the number of reproductive individuals in the no grazing treatment, the number in the heavy grazing treatment decreased significantly, and the negative correlation between reproductive individuals and nonreproductive individuals changed from a full-scale negative correlation to a small-scale negative correlation and a large-scale positive correlation. …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Examining the effects of the histone methyltransferase inhibitor BIX-01294 on histone modifications and gene expression in both a clinical population and mouse models by Kayla A. Chase (6824141)

“…In BDNF conditional knockdown animals, BIX administration was able to significantly rescue Bdnf9a mRNA levels in ChAT and D1 Bdnf conditional knockdown mice. …”

CaD prevents the decrease in tight junction protein levels and the increase in HUVECs permeability induced by VEGF₁₆₅. by Florence Njau (8298954)

Decrease in gastrin-, histidine decarboxylase-, and somatostatin mRNA due to the <i>H. pylori</i> B128 WT-infection. by Tobias Wiedemann (266622)

Effect of i.c.v. infusion of rrIL-1ra on poly I:C-induced decrease in spontaneous activity. by Masanori Yamato (534076)

DDX5 and DDX17 decrease viral gene expression during KSHV lytic reactivation in iSLK.219 cells. by Praneet Kaur Sandhu (21156149)

Figure S1 - Two Naturally Occurring Terpenes, Dehydrocostuslactone and Costunolide, Decrease Intracellular GSH Content and Inhibit STAT3 Activation by Elena Butturini (220699)

“…<p><b>Effect of DCE and CS on STAT3 activation in DLD-1 cells.</b> (a) EMSA shows that DCE and CS dose-dependently decrease DNA-binding activity of STAT3 activated by 20 ng/ml IL6 in DLD-1 cells. …”

B6.lpr DN T cells decrease GVHD target organ infiltration by alloreactive CD4⁺ T cells. by Stephen C. Juvet (127134)

S1 Data - Adaptive integrated intervention approaches for schistosomiasis elimination in Pemba: A 4-year intervention study and focus on hotspots by Lydia Trippler (10136316)

The impact of the interaction between PAC and CPAM dosage on sewage turbidity. (a) Contour diagram; (b) 3D surface diagram. by Peng Zhao (128233)