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linear decrease » linear increase (Expand Search)
large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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35501
Image_1_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp...
Published 2022“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”
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35502
Image_2_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp...
Published 2022“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”
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35503
DataSheet_1_T-regulatory cells require Sin3a for stable expression of Foxp3.pdf
Published 2024“…Mice also showed effector T-cell activation, autoantibody production, and widespread tissue injury. Mechanistically, Sin3a deletion resulted in decreased transcription of Foxp3 with a complete lack of CNS2 CpG demethylation. …”
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35504
Image_1_A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.pdf
Published 2019“…<p>Fabry disease (FD) is a rare X-linked α-galactosidase A (GLA) deficiency, resulting in progressive lysosomal accumulation of globotriaosylceramide (Gb3) in a variety of cell types. …”
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35505
Inkjet Nanoinjection for High-Thoughput Chemiluminescence Immunoassay on Multicapillary Glass Plate
Published 2013“…The analysis time and reagent consumption were significantly decreased. The IgA concentrations in saliva samples were determined after 10000-fold dilution by the developed ELISA system showing comparable results by conventional immune assay with 96-wells. …”
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35506
DataSheet_1_Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation.pdf
Published 2022“…<p>The placental inflammatory processes induced maternally result in preterm birth (PTB). Serum amyloid A (SAA) is a well-known biomarker of inflammation. …”
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35507
Inkjet Nanoinjection for High-Thoughput Chemiluminescence Immunoassay on Multicapillary Glass Plate
Published 2013“…The analysis time and reagent consumption were significantly decreased. The IgA concentrations in saliva samples were determined after 10000-fold dilution by the developed ELISA system showing comparable results by conventional immune assay with 96-wells. …”
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35508
Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension
Published 2015“…Metabolic stability and agonist potency were optimized through modification of the linear side chain. Compound <b>12b</b> (MRE-269, ACT-333679) was identified as a potent and highly selective prostacyclin receptor agonist. …”
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35509
Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension
Published 2015“…Metabolic stability and agonist potency were optimized through modification of the linear side chain. Compound <b>12b</b> (MRE-269, ACT-333679) was identified as a potent and highly selective prostacyclin receptor agonist. …”
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35510
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35511
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35512
Data_Sheet_1_Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet.docx
Published 2022“…<p>Resveratrol (RES) is considered to be an activator of AMP-activated protein kinase (AMPK) with many reported health benefits. Polydatin (POD) is a natural precursor and glycosylated form of RES. …”
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35513
Image_2_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.jpeg
Published 2022“…Total antioxidant capacity (T-AOC) were markedly decreased and positively associated with FOXO3a in AS. …”
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35514
Image_5_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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35515
Image_1_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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35516
Data_Sheet_3_Transcript Isoforms of SLC7A11-AS1 Are Associated With Varicocele-Related Male Infertility.docx
Published 2020“…Overexpression of SLC7A11-AS1 isoform 6 in NT2 and NCCIT cell lines resulted in a significant downregulation of SLC7A11 gene expression, which consequently decreased GSH levels and concomitantly increased ROS levels and enhanced lipid peroxidation, which jeopardized cell survival and promoted cell death. …”
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35517
Table_2_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.DOCX
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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35518
Image_4_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF
Published 2021“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”
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35519
Image_1_Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A.tif
Published 2020“…Increasing the dose of GLA-SE from 2.5 to 5 μg in pre-exposed volunteers improved anti-P27A affinity and decreased the number of recognized epitopes. …”
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35520
Table_1_FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis.docx
Published 2022“…Total antioxidant capacity (T-AOC) were markedly decreased and positively associated with FOXO3a in AS. …”