Table_2_ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5.XLSX by Chaoqin Shen (3763807)

“…Mechanistically, CO-IP and ChIP assays indicated that ALKBH4 competitively bound WDR5 (a key component of histone methyltransferase complex) and decreased H3K4me3 histone modification on the target genes including MIR21.…”

Image_2_ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5.JPEG by Chaoqin Shen (3763807)

“…Mechanistically, CO-IP and ChIP assays indicated that ALKBH4 competitively bound WDR5 (a key component of histone methyltransferase complex) and decreased H3K4me3 histone modification on the target genes including MIR21.…”

Image_1_Birth Weight and Subsequent Risk of Total Leukemia and Acute Leukemia: A Systematic Review and Meta-Analysis.JPEG by Hailuo Che (11470654)

“…In addition, compared with NBW population, there is stronger evidence supporting a significantly increased risk of subsequent ALL in HBW population, and a decreased risk in LBW population in a dose-dependent manner. …”

Table_3_ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5.XLSX by Chaoqin Shen (3763807)

“…Mechanistically, CO-IP and ChIP assays indicated that ALKBH4 competitively bound WDR5 (a key component of histone methyltransferase complex) and decreased H3K4me3 histone modification on the target genes including MIR21.…”

Image_1_ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5.JPEG by Chaoqin Shen (3763807)

“…Mechanistically, CO-IP and ChIP assays indicated that ALKBH4 competitively bound WDR5 (a key component of histone methyltransferase complex) and decreased H3K4me3 histone modification on the target genes including MIR21.…”

DataSheet1_Effects of Climate Change on Hydrological Indicators of Subsurface Drainage for a Representative French Drainage Site.docx by Alexis Jeantet (12971120)

“…We used a uniquely large and comprehensive range of 17 hydrological indicators (HIs), describing the temporal dynamics of drainage season, soil saturation, drained water balance and flood events. …”

Data_Sheet_1_Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture.PDF by Carlos García-Crespo (13191666)

“…<p>We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection. …”

Enhancement of cell proliferation and decrease of myofibroblast differentiation, inflammation and fibrosis after stem cell therapy on acute kidney ischemia and reperfusion injury. by Marina Gabriela Monteiro Carvalho Mori da Cunha (785732)

Risk of Hormone Escape in a Human Prostate Cancer Model Depends on Therapy Modalities and Can Be Reduced by Tyrosine Kinase Inhibitors by Charlotte Guyader (145409)

“…Combination of castration with a Her-2/neu inhibitor decreased recurrence risk (0.17) and combination with an mTOR inhibitor prevented it. …”

DataSheet_1_Microbiological profile of diabetic foot infections in China and worldwide: a 20-year systematic review.docx by Yu-dun Qu (17869511)

“…We aimed to determine the incidence and antibiotic susceptibility of DFI pathogens worldwide, focusing on Asia and China.</p>Methods<p>Through a comprehensive literature search, we identified published studies on organisms isolated from DFI wounds from January 2000 to December 2020.…”

The Critical Role of N- and C-Terminal Contact in Protein Stability and Folding of a Family 10 Xylanase under Extreme Conditions by Amit Bhardwaj (246777)

“…Recent studies have shown that a large proportion of proteins have their N- and C-terminal elements in close contact and suggested they play a role in protein folding and stability. …”

Ultrasensitive and Highly Compressible Piezoresistive Sensor Based on Polyurethane Sponge Coated with a Cracked Cellulose Nanofibril/Silver Nanowire Layer by Shuaidi Zhang (2853290)

“…The electrical conductivity and mechanical property of the conductive CA@PU sponge could be effectively tuned through changing the dip-coating number. As a piezoresistive sensor, the sponge exhibited the capability of detecting both small and large motions over a wide compression strain range of 0–80%. …”

<b>Predicting cardiac and renal responses to sacubitril/valsartan with a mathematical model of heart failure with preserved ejection fraction</b> by John Clemmer (11226783)

“…Recently, clinical trials investigating sacubitril/valsartan, a dual angiotensin receptor blocker (ARB) and neprilysin inhibitor (ARNI), demonstrated greater lowering of blood pressure (BP) and NT-proBNP in HFpEF patients as compared to ARB alone. …”

Table 1_Predicted skeletal muscle index as a scalable marker for sarcopenia risk and mortality in older Chinese adults.docx by Ya Liu (205636)

“…To our knowledge, this represents the first large-scale validation of pSMI’s prognostic value for mortality risk independent of baseline sarcopenia in a nationally representative older Chinese cohort. …”

K294E change in the rotavirus factory forming protein NSP2 stabilizes a rare C-terminal conformation by Sarah L. Nichols (22316634)

“…These results provide mechanistic insights into how a single amino acid change in the NSP2 C-terminus can have large effects on structural ensemble, shedding light on features of the protein that underpin RV viroplasm formation.…”

DataSheet_1_Microbiological profile of diabetic foot infections in China and worldwide: a 20-year systematic review.docx by Yu-dun Qu (17869511)

“…We aimed to determine the incidence and antibiotic susceptibility of DFI pathogens worldwide, focusing on Asia and China.</p>Methods<p>Through a comprehensive literature search, we identified published studies on organisms isolated from DFI wounds from January 2000 to December 2020.…”

Data_Sheet_1_Causal associations between gut microbiota and Cholestatic liver diseases: a Mendelian randomization study.docx by Jiaqi Yang (4380466)

“…</p>Result<p>This two-sample MR study indicated that the order Bacillales, family Peptostreptococcaceae, family Ruminococcaceae, genus Anaerotruncu was associated with a decreased risk of developing PBC, and that order Selenomonadales, family Bifidobacteriaceae may be factors that increase the risk of PBC. …”

Metabolomic profile and nucleoside composition of <i>Cordyceps nidus</i> sp. nov. (Cordycipitaceae): A new source of active compounds by Juan Chiriví (4164649)

“…Nevertheless, harvesting wild specimens has become a challenge given that natural populations of the fungus are decreasing and because large-scale culture of it has not yet been achieved. …”

Data_Sheet_1_A Bayesian Modeling Approach to Examine the Role of Testosterone Administration on the Endowment Effect and Risk-Taking.pdf by Mikhail Votinov (527365)

“…Compared to placebo, testosterone administration increased risk-taking under the positive framing (very large effect size) and decreased under the negative framing (moderate to small). …”

Most miRNAs in Ago1 RISC are stable with age whereas transposon siRNAs in Ago2 RISC decrease with age. by Siobhan Gartland (14129274)

“…<p>Small RNAs immunoprecipitated with Ago1 RISC or Ago2 RISC from young (5 day old) or old (35 day old) whole flies were sequenced and mapped to known <i>Drosophila</i> miRNAs and transposons. (A) miRNAs in Ago1 RISC from old and young males are plotted as percentage of mapped reads. miR-34-5p increases with age by more than 2-fold while miR-14-3p does not. …”