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46461
Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy
Published 2024“…Metronomic chemotherapy (MCT), characterized by the continuous administration of chemotherapeutics at a lower dose without prolonged drug-free periods, has garnered significant attention over the last 2 decades. …”
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46462
Physical activity in pregnancy prevents gestational diabetes: A meta-analysis
Published 2020“…Data obtained were synthesised using a bias-adjusted model of meta-analysis. ResultsA total of 1467 adult women in 11 eligible trials were included. …”
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46463
A decision support system for automating document retrieval and citation screening
Published 2021“…In two cases, our model yielded a better performance over the benchmark review datasets. …”
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46464
A feeding protocol for delivery of agents to assess development in Varroa mites
Published 2017“…Although supplementation with <i>Bombyx mori</i> Bm5 cells increased the amount of hemolymph consumed per mite, there was a significant decrease in the percentage of mites that fed and survived. …”
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46465
Modulating Supramolecular Reactivity Using Covalent “Switches” on a Pyrazole Platform
Published 2012“…Furthermore, the overall electrostatic charge on the key binding sites on the pyrazole backbone can be modulated by using specific covalent switches, which in turn can increase (or decrease) the success rate for a reaction.…”
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46466
Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene
Published 2011“…<div><h3>Background</h3><p>Epidemiological studies have shown that unfiltered coffee consumption is associated with a low incidence of cancer. This study aims to identify the effects of kahweol, an antioxidant diterpene contained in unfiltered coffee, on angiogenesis and key inflammatory molecules.…”
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46467
Table_2_Communication of Diagnosis of Infertility: A Systematic Review.DOC
Published 2021“…Their communication skills play a central role in improving patients' coping abilities and adherence to infertility treatments. …”
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46468
Filgrastim loading in PLGA and SLN nanoparticulate system: a bioinformatics approach
Published 2020“…PLGA and tripalmitin systems were equalized at 310 °C, at 1 bar pressure with Berendsen barostat for 200 ps using a v-rescale thermostat for 100 ps. Atomistic MD simulations of four model system and mass density of interacting systems were calculated.…”
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46469
Summary sketch of a L2/3 SNHL pyramidal neuron
Published 2011“…An upward arrow indicates increased whereas a downward arrow indicates decreased function. …”
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46470
Protein Crystallization in the Presence of a Metastable Liquid–Liquid Phase Separation
Published 2020“…In no case evidence of nucleation inside the DLP is observed. SAXS and SANS show a monotonous growth of the crystals and a decrease of the overall material in the sample. …”
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46471
Delirium in the elderly: A systematic review of pharmacological and non-pharmacological treatments
Published 2017“…Databases used were: MEDLINE (PubMed), EMBASE, Cochrane CENTRAL and LILACS from inception to January 6th, 2016. RESULTS: A total of ten articles were selected. The six non-pharmacological intervention studies showed no impact on duration of delirium, mortality or institutionalization, but a decrease in severity of delirium and improvement in medium-term cognitive function were observed. …”
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46472
Effects of a mitochondrial–nuclear interaction on adult fecundity and sensory structures.
Published 2013“…<p>(A) The <i>simw<sup>501</sup></i> mtDNA decreases the total number of eggs females laid by 50% only in the <i>OreR</i> nuclear background (mtDNA×nuclear interaction: <i>F</i> = 9.772, <i>P</i> = 0.004, <i>N</i> = 6–11 females per genotype). …”
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46473
Attentional scope is reduced by Internet use: A behavior and ERP study
Published 2018“…<div><p>As a crucial living environment, the Internet shapes cognition. …”
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46474
Drug repositioning against COVID-19: a first line treatment
Published 2021“…The resulting drugs from the present study in combination and in cocktails from the arsenal of existing drugs could reduce the translational distance and could offer substantial clinical benefit to decrease the burden of COVID-19 illness. This also creates a roadmap for subsequent viral diseases that emerge.…”
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46475
Shear depletes TSP-1 via a thiol-dependent mechanism.
Published 2013“…The labeled proteins were either analyzed directly (left two lanes) or after affinity-purification using Streptavidin-coupled beads (right two lanes). Shearing led to a dramatic decrease in intensity of the HRP reaction in select regions. …”
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46476
Socioeconomic inequalities in health in the context of multimorbidity: A Korean panel study
Published 2017“…Using three waves of Korea Health Panel, data of 19,942 observations with repeated measure were constructed to ensure a temporal sequence between three socioeconomic measures (i.e., poverty, employment status, and education) and multimorbidity with a <i>t</i> to <i>t</i>+1 year transition. …”
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46477
<i>Δhyr1</i> exhibits a virulence defect.
Published 2011“…<p>Δ<i>hyr1</i> mutants display a decrease in pathogenicity compared to wild type, on susceptible barley and rice. …”
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46478
KGF mRNA is a primary target for miR-155.
Published 2009“…(C) Co-transfection of human or murine pre-miR-155 or pre-miR-Neg and of human or murine KGF 3′UTR-derived psiCHECK™-2 construct in HEK 293 and NIH 3T3 cells show a significant decrease in normalized luciferase activity 48 h post-transfection in both cell types. …”
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46479
Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale
Published 2015“…Importantly, nearly all proteins identified in both the UVPD and optimized HCD analyses demonstrated a substantial increase in confidence in identification (as defined by an average decrease in <i>E</i> value of ∼40 orders of magnitude) due to the higher number of matched fragment ions. …”
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46480
Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale
Published 2015“…Importantly, nearly all proteins identified in both the UVPD and optimized HCD analyses demonstrated a substantial increase in confidence in identification (as defined by an average decrease in <i>E</i> value of ∼40 orders of magnitude) due to the higher number of matched fragment ions. …”