Sar1, a Novel Regulator of ER-Mitochondrial Contact Sites by Karin B. Ackema (423507)

“…<div><p>Endoplasmic reticulum (ER)—mitochondrial contact sites play a pivotal role in exchange of lipids and ions between the two organelles. …”

Bidirectional Control of Absence Seizures by the Basal Ganglia: A Computational Evidence by Mingming Chen (535268)

“…It has been thus postulated that the basal ganglia might play key roles in the modulation of absence seizures, but the relevant biophysical mechanisms are still not completely established. Using a biophysically based model, we demonstrate here that the typical absence seizure activities can be controlled and modulated by the direct GABAergic projections from the substantia nigra pars reticulata (SNr) to either the thalamic reticular nucleus (TRN) or the specific relay nuclei (SRN) of thalamus, through different biophysical mechanisms. …”

Hsp70 reduces aSyn oligomerization and toxicity in living cells. by Tiago Fleming Outeiro (199633)

“…Immunoblot of an SDS-PAGE of the same samples as in E showing Hsp70 overexpression does not lead to decreased levels of GN-link-aSyn nor aSynGC. F. Quantification of the SDS-PAGE confirms that Hsp70 does not reduce the protein levels of GN-link-aSyn nor aSyn-GC.…”

Structural Stability of Ruthenium Nanoparticles: A Density Functional Theory Study by Yusuke Nanba (1343925)

“…Together with the structural stability, the icosahedral fcc structure shows a unique electronic structure compared with the other structures. …”

A Rice <i>Stowaway</i> MITE for Gene Transfer in Yeast by Isam Fattash (414334)

“…Surprisingly, the orientation of a cargo gene (<i>neo</i>) on a construct bearing dual reporter genes (<i>gfp</i> and <i>neo</i>) was found to have a dramatic effect on transposition frequency. …”

Torpor bout length (TBL) as a function of WNS severity score. by DeeAnn M. Reeder (157774)

“…Individual data points are shown as open circles, the median is indicated by a line. As severity of infection increased, torpor bout length significantly decreased (bats aroused more frequently from torpor.…”

Rapamycin treatment induced a T cells lymphopenia sparing B cells. by Nicolas Prevel (483113)

“…<p>A: absolute lymphocyte number in draining lymph nodes, spleen, and non-draining lymph nodes is decreased in rapamycin-treated mice compare to controls in a dose-dependent fashion. …”

Cryopreserved hMSCs exhibit a reduced F-actin-length. by Yannik Müllers (6265511)

“…<p>(A) Boxplots show the difference of F-actin-length between identical cells before and after cryopreservation with varying recovery time. …”

Gangliosides, GT1b and its interactions with BoNT/A. by Pål Stenmark (270960)

“…<p>A: GT1b, GD1a and GM1 shown in decreasing order of affinity towards BoNT/A; also GD1b and GQ1b are shown. …”

Counterion Blockade in a Heterogeneously Charged Single-File Water Channel by Shusong Zhang (470905)

“…Here, we find that the cations can be strongly bound to the surface charge, which blocks the ionic transport in a single-file water channel, causing nonlinear current–voltage curves. …”

The monomeric form of CsgA remains stable in the presence of LL-37. by Ylva Kai-Larsen (289552)

“…The CD spectrum reveals that CsgA alone exhibits a fiber-like structure with weak beta-sheet conformation and a decreased solubility. …”

Women Tend to Defect in a Social Dilemma Game in Southwest China by Riccardo Pansini (213187)

“…In this region, women have customarily held less economic power and they are used to obtain a payoff typically lower than men. We suggest that the women’s willingness to invest in cooperation has decreased throughout evolutionary time, providing us with an illustration of a culturally-driven shift towards a disparity in gender cooperation interests.…”

On the sustainability of a family planning program in Nigeria when funding ends by Ilene S. Speizer (7435022)

“…This article presents the results of a natural experiment where the Nigerian Urban Reproductive Health Initiative Phase I programming ended in early 2015 and Phase II activities continued in a subset of cities. …”

A Risk-Based Framework for Assessing the Effectiveness of Stratospheric Aerosol Geoengineering by Angus J. Ferraro (522417)

“…We present a simple, intuitive risk-based framework for classifying these impacts according to whether geoengineering increases or decreases the risk of substantial climate change, with further classification by the level of existing risk from climate change from increasing carbon dioxide concentrations. …”

The LDL-HDL Profile Determines the Risk of Atherosclerosis: A Mathematical Model by Wenrui Hao (534305)

“…<div><p>Atherosclerosis, the leading death in the United State, is a disease in which a plaque builds up inside the arteries. …”

Furin Targeted Drug Delivery for Treatment of Rhabdomyosarcoma in a Mouse Model by Katarina Hajdin (249498)

“…By panning with a phage-displayed cyclic random peptide library we selected a peptide with strong affinity for RMS <em>in vitro</em> and <em>in vivo</em>. …”

Application research and progress of microalgae as a novel protein resource in the future by S. L. Ma (22409308)

“…They offer a protein balance comparable to meat, making them a sustainable protein source with health benefits like antioxidants, cardiovascular support, and anti-inflammatory properties. …”

Acoustic Divergence with Gene Flow in a Lekking Hummingbird with Complex Songs by Clementina González (280744)

“…We contrasted estimates of genetic differentiation, genetic structure, and gene flow across leks from microsatellite loci of wedge-tailed sabrewings with measures for acoustic signals involved in mating derived from recordings of males singing at leks throughout eastern Mexico. We found a strong acoustic structure across leks and geography, where lek members had an exclusive assemblage of syllable types, differed in spectral and temporal measurements of song, and song sharing decreased with geographic distance. …”

Enhanced boron removal by electricity generation in a microbial fuel cell by Ping, Qingyun

“…Boron needs to be removed during desalination, because excessive boron in the product water for irrigation can deteriorate plant growth. In this study, a microbial fuel cell (MFC) equipped with anion exchange membrane (AEM) was proposed and investigated to remove boron via two successive steps: boric acid is ionized to borate ions in the presence of high pH as a result of cathode reaction, and borate ions are transported across AEM driven by electricity generation. …”
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Interpretation of Genomic Variants Using a Unified Biological Network Approach by Ekta Khurana (386863)

“…<div><p>The decreasing cost of sequencing is leading to a growing repertoire of personal genomes. …”