Effect of L-type Ca²⁺ channel activators and blockers on A_2AR mRNA and protein levels in PC12 cells. by Zhiyun Wang (360002)

“…<p>(<b>A</b>) The L-type Ca²⁺ channel activator Bay K8644 increased A_2AR mRNA levels in PC12 cells compared to untreated controls while the L-type Ca²⁺ blocker Nifedipine, as well as SMF exposure, decreased A_2AR mRNA levels after 6.0 h of exposure (<i>p</i><0.05 for each test condition compared to control for n≥3 independent experiments). …”

Investigation of External Quantum Efficiency Roll-Off in OLEDs Using the Mean-Field Steady-State Kinetic Model by Alexandra R. McIsaac (9027794)

“…This study utilizes a new formalismmean-field steady-state kineticsthat can rapidly simulate macroscopic device characteristics based on molecular-scale rates. …”

Data_Sheet_1_A Deep Learning Approach Validates Genetic Risk Factors for Late Toxicity After Prostate Cancer Radiotherapy in a REQUITE Multi-National Cohort.docx by Michela Carlotta Massi (9122257)

“…The purpose of this project was to analyse a cohort of patients recruited into REQUITE using a deep learning algorithm to identify patient-specific features associated with the development of toxicity, and test the approach by attempting to validate previously published genetic risk factors.…”

Insulin levels (mean±SEM) in infants on postnatal day of life 45 and premenopausal female adults.^* by Lindsey E. Nicol (124842)

“…<p>*The ivGTT parameters have been previously published for female adults demonstrating decreased insulin sensitivity and disposition index <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106527#pone.0106527-Eisner1" target="_blank">[24]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106527#pone.0106527-Abbott5" target="_blank">[33]</a> and for infants reporting increased insulin sensitivity and disposition index <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106527#pone.0106527-Abbott2" target="_blank">[9]</a>. …”

Nkx3.1 function is required to regulate brain pericyte numbers. by Suchit Ahuja (16440789)

“…<i>1</i>^−/− have decreased CtA vessel diameter in comparison to <i>nkx3</i>.…”

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes by John R. Cashman (354526)

“…Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (I_NaL) SCN5A mutations that prolongs cardiac action potential (AP) and enhances I_NaL current. …”

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells by David A. Tumbarello (680437)

“…Furthermore, ovarian cancer cells have a reduced motility and decreased response to the chemotherapeutic agent paclitaxel when plated on ECM derived from mesothelial cells lacking SPARC compared to control mesothelial-derived ECM. …”

Green-lipped mussel extract reduced pain in MIA-injected rats. by JooYeon Jhun (3797404)

Age- and gender-adjusted marginal mean cholesterol levels (mg/dl) by DENV infection status and day of illness. by Hope H. Biswas (179729)

“…In contrast, HDL-C levels were significantly lower only on days 5–7 of illness (p<0.001). HDL-C levels followed a similar trajectory among both dengue-positive and dengue-negative patients, decreasing from day 2 to day 6–7 of illness before stabilizing or increasing slightly on day 7–8 of illness. …”

Data_Sheet_1_Creation of a Low-Alcohol-Production Yeast by a Mutated SPT15 Transcription Regulator Triggers Transcriptional and Metabolic Changes During Wine Fermentation.PDF by Qing Du (1610224)

“…Here the global transcription machinery engineering (gTME) technology was used to engineer a yeast strain with decreased ethanol yield, based on the mutation of the SPT15 gene. …”

RNAi of electron transport chain components in glutamate neurons increases sleep in 10 day old flies. by Jessie E. Landis (16378731)

Image_1_SmTAL-9, a Member of the Schistosoma mansoni Tegument Allergen-Like Family, Is Important for Parasite Survival and a Putative Target for Drug/Vaccine Development.tiff by Wilma Patrícia de Oliveira Santos Bernardes (5922452)

“…Also, we cloned and expressed a recombinant form of Smtal-9 and evaluated its ability to induce protection in mice. …”

Image_2_SmTAL-9, a Member of the Schistosoma mansoni Tegument Allergen-Like Family, Is Important for Parasite Survival and a Putative Target for Drug/Vaccine Development.tiff by Wilma Patrícia de Oliveira Santos Bernardes (5922452)

“…Also, we cloned and expressed a recombinant form of Smtal-9 and evaluated its ability to induce protection in mice. …”

Image_3_SmTAL-9, a Member of the Schistosoma mansoni Tegument Allergen-Like Family, Is Important for Parasite Survival and a Putative Target for Drug/Vaccine Development.tiff by Wilma Patrícia de Oliveira Santos Bernardes (5922452)

“…Also, we cloned and expressed a recombinant form of Smtal-9 and evaluated its ability to induce protection in mice. …”

The fit of the model to the calibration data for CETP deficiency: HDL-C (panel A), ApoA-I (panel B), LDL-CE (panel C) and VLDL-CE (panel D). by James Lu (534847)

“…<p>The data are as shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003509#pcbi-1003509-t006" target="_blank">Table 6</a>, obtained by pooling HDL-C and ApoA-I data from references <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003509#pcbi.1003509-Inazu1" target="_blank">[81]</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003509#pcbi.1003509-Asztalos4" target="_blank">[83]</a> and LDL-CE, VLDL-CE data from references <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003509#pcbi.1003509-Ouguerram1" target="_blank">[20]</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003509#pcbi.1003509-Schwartz2" target="_blank">[21]</a>. …”

DataSheet_1_A metabolome genome-wide association study implicates histidine N-pi-methyltransferase as a key enzyme in N-methylhistidine biosynthesis in Arabidopsis thaliana.pdf by Kai Uchida (16076942)

“…Knockout and overexpression of A. thaliana lines of this gene had significantly decreased and increased N-methylhistidine contents, respectively. …”

Data_Sheet_1_Case report: Dancing in the dark: A critical single case study engaging a blind father in the rehabilitation journey of his visually impaired child.docx by Livio Provenzi (4739583)

“…The return time to the “active interaction” region of interest decreased progressively. A reduction was observed also for the time spent by the dyad in the region “no vocal contact.”…”

Accuracy of estimates of <i>T</i>₁ (A) and <i>T</i>₂ (B), and ALDER estimates of admixture time (C) as a function of other parameters. by Mason Liang (427373)

“…ALDER estimates a single admixture time which corresponds to <i>T</i>₁ = 0.…”

Designing a Flexible and Transparent Ultrarapid Electrothermogenic Film Based on Thermal Loss Suppression Effect: A Self-Fused Cu/Ni Composite Junctionless Nanonetwork for Effectiv... by Ryohei Yoshikawa (3846331)

“…This two-step wet process enables the formation of a junctionless network composed of a copper/nickel alloy. …”

A Germanium Isocyanide Complex Featuring (n → π*) Back-Bonding and Its Conversion to a Hydride/Cyanide Product via C–H Bond Activation under Mild Conditions by Zachary D. Brown (1966780)

“…Reaction of the diarylgermylene Ge­(Ar^Me₆)₂ [Ar^Me₆ = C₆H₃-2,6-(C₆H₂-2,4,6-(CH₃)₃)₂] with <i>tert</i>-butyl isocyanide gave the Lewis adduct species (Ar^Me₆)₂GeCNBu^<i>t</i>, in which the isocyanide ligand displays a decreased C–N stretching frequency consistent with an n → π* back-bonding interaction. …”