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linear decrease » linear increase (Expand Search)
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48521
Dopamine D<sub>3</sub>/D<sub>2</sub> Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders
Published 2023“…Cariprazine and two lead analogues, <b>13a</b> and <b>13e</b>, decreased cocaine self-administration (FR2; 1–10 mg/kg, i.p.) in rats, suggesting that partial agonists/antagonists with modest D<sub>3</sub>R/D<sub>2</sub>R selectivity may be effective in treating PSUD and potentially comorbidities with other affective disorders.…”
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48522
Influence of the ferric uptake regulator (Fur) protein on pathogenicity in <i>Pectobacterium carotovorum</i> subsp. <i>brasiliense</i>
Published 2017“…Consistent with phenotypic results, qRT-PCR results demonstrated that Fur down-regulates genes which encode proteins associated with: iron uptake (HasA-extracellular heme-binding protein and Ferrodoxin-AED-0004132), stress response (SodC-superoxide dismutase), plant cell wall degrading enzymes (PrtA and CelV) and motility (FlhC and MotA). …”
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48523
Atorvastatin Alleviates Experimental Diabetic Cardiomyopathy by Regulating the GSK-3β-PP2Ac-NF-κB Signaling Axis
Published 2016“…Our results showed that, in HG-cultured cardiomyocytes, phosphorylation of GSK-3β was decreased, while that of the PP2A catalytic subunit C (PP2Ac) and IKK/IкBα was increased, followed by NF-кB nuclear translocation and apoptosis. …”
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48524
DataSheet1_Radiation therapy affects YAP expression and intracellular localization by modulating lamin A/C levels in breast cancer.PDF
Published 2022“…As supposed, we found that the effects of radiation on YAP nucleus/cytoplasmic expression ratio, increasing in healthy cells and decreasing in tumour ones, were accompanied by lower and higher lamin A/C levels in MCF10A and MDA-MB-231 cells, respectively. …”
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48525
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48526
Relationships between the <i>Osteocalcin</i> Gene Polymorphisms, Serum Osteocalcin Levels, and Hepatitis B Virus-Related Hepatocellular Carcinoma in a Chinese Population
Published 2015“…<div><p>Background</p><p>Available evidence has demonstrated that osteocalcin may play a role in pathogenesis of cancer, and mutation of the <i>osteocalcin</i> gene may be involved in the cancer development. …”
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48527
Lagged Effect of Diurnal Temperature Range on Mortality in a Subtropical Megacity of China
Published 2013“…</p> <h3>Results</h3><p>A non-linear relationship was consistently found between extreme DTR and mortality. …”
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48528
Δ40p53 alters WTp53 function; Δ40p53:WTp53 fails to induce eRNA transcription despite similar genomic occupancy vs. WTp53.
Published 2021“…<p><b>(A)</b> Summary of PRO-seq data for WTp53 (y-axis) vs. …”
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48529
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48530
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48531
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48532
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48533
A 19-years study of the dental procedures performed in the Brazilian Unified Health System
Published 2019“…Exodontia presented a tendency to increase in the North macroregion (p=0.046), while the Midwest presented a decrease of it (p=0.049). …”
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48534
A 19-years study of the dental procedures performed in the Brazilian Unified Health System
Published 2019“…Exodontia presented a tendency to increase in the North macroregion (p=0.046), while the Midwest presented a decrease of it (p=0.049). …”
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48535
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48536
The effects of low-carbohydrate diets on cardiovascular risk factors: A meta-analysis
Published 2020“…Low-carbohydrate diet interventions lasting less than 6 months were associated with a decrease of -0.23mmol/l (95% confidence interval -0.32 to -0.15), while those lasting 12–23 months were associated with a decrease of -0.17mmol/l (95% confidence interval -0.32 to -0.01). …”
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48537
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48538
Cellular response to 5FU similar in WTp53 vs. Δ40p53:WTp53 cells, but driven by distinct TFs.
Published 2021“…<p><b>(A)</b> Cell cycle analysis (PI); chart (inset) represents the average of 3 experiments (bars = SEM). …”
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48539
Table_3_Comparing Discounting of Potentially Real Rewards and Losses by Means of Functional Magnetic Resonance Imaging.xlsx
Published 2022“…In each trial, participants had to choose between a smaller immediate loss/win and a larger loss/win at a fixed delay of two weeks. …”
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48540
Table_2_Comparing Discounting of Potentially Real Rewards and Losses by Means of Functional Magnetic Resonance Imaging.xlsx
Published 2022“…In each trial, participants had to choose between a smaller immediate loss/win and a larger loss/win at a fixed delay of two weeks. …”