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49461
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49462
Retinal degeneration phenotype in the Rp1-Q662X mice. A.
Published 2012“…Significant differences (P<0.05) indicated by *. Note that the rod-a waves of the ki/ki mice were significantly decreased at 1 month of age. …”
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49463
Video2_A visualization system for erectile vascular dynamics.MP4
Published 2022“…The corpus cavernosum (CC) in the upper (dorsal) part of the penis plays a major role in regulating blood flow inside the penis. …”
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49464
Establishment and Characterization of a Newly Established Diabetic <i>Gerbil</i> Line
Published 2016“…<div><p>Objectives</p><p>We aimed to selectively breed a spontaneous diabetic <i>gerbil</i> when a sub-line of inbred <i>gerbil</i> showed increased blood glucose levels was found recently. …”
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49465
A Time Series Evaluation of the FAST National Stroke Awareness Campaign in England
Published 2014“…</p><p>Results</p><p>Before the campaign, emergency admissions (and patients admitted via accident and emergency [A&E]) and thrombolysis activity was increasing significantly over time, whereas emergency admissions via general practitioners (GPs) were decreasing significantly. …”
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49466
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49467
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49468
Internal retroactivity makes a module more robust to interconnection at the expense of speed.
Published 2014“…<p>(A) The module consists of a single negatively autoregulated node, whereas the context comprises nodes repressed by the TF in the module. …”
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49469
Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
Published 2021“…The nanopores absorbed up to 28 and 24 molecules of CH4 and CO2, respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å2 for each. Although the nanopore was filled spatially by the molecules, its surface still has an affinity to absorb more gas molecules energetically. …”
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49470
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49471
The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>
Published 2019“…The proteasome is receiving attention as a potential drug target for treatment of a variety of infectious parasitic diseases, but it has been understudied in the schistosome. …”
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49472
Statins and Hip Fracture Prevention – A Population Based Cohort Study in Women
Published 2012“…In the hypertension and the population cohorts, the rates were 2.0 per 1000 py (312 fractures per 157 090 py) and 1.0 per 1000 py (212 fractures per 216 329 py), respectively. Adjusting for a propensity score and individual variables strongly predicting the outcome, good adherence to statins for five years was associated with a 29% decreased risk (HR 0.71; 95% CI 0.58–0.86) of a low-energy hip fracture in comparison with adherent use of hypertension drugs. …”
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49473
The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>
Published 2019“…The proteasome is receiving attention as a potential drug target for treatment of a variety of infectious parasitic diseases, but it has been understudied in the schistosome. …”
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49474
The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>
Published 2019“…The proteasome is receiving attention as a potential drug target for treatment of a variety of infectious parasitic diseases, but it has been understudied in the schistosome. …”
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49475
Withanolide A Prevents Neurodegeneration by Modulating Hippocampal Glutathione Biosynthesis during Hypoxia
Published 2014“…Supplementation of withanolide A during hypoxic exposure increased GSH level, augmented GSH dependent free radicals scavenging system and decreased the number of caspase and hoescht positive cells in hippocampus. …”
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49476
Pyrvinium inhibits WNT signaling in a CK1α dependent manner.
Published 2014“…<p><b>A</b>. The expression of the WNT target gene: <i>AXIN2</i> was determined from NIH 3T3 cells expressing control or <i>CK1α</i>-specific shRNAs. …”
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49477
The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>
Published 2019“…The proteasome is receiving attention as a potential drug target for treatment of a variety of infectious parasitic diseases, but it has been understudied in the schistosome. …”
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49478
Data_Sheet_1_Suppression of the Lycopene Cyclase Gene Causes Downregulation of Ascorbate Peroxidase Activity and Decreased Glutathione Pool Size, Leading to H2O2 Accumulation in Eu...
Published 2021“…In the present study, we identified an uncharacterized gene encoding the E. gracilis β-carotene synthetic enzyme lycopene cyclase (EgLCY) and discovered a relationship between EgLCY-mediated carotenoid synthesis and the reactive oxygen species (ROS) scavenging system ascorbate-glutathione cycle. …”
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49479
Anatomical connectivity matrix and resulting functional connectivities as a function of delay distribution.
Published 2014“…<p><b>A</b>: Sparse neuroanatomical coupling matrix serving as structural connectivity (connections are given in yellow). …”
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49480
Telomestatin induces a delocalization of Topo III from PML and TRF2.
Published 2009“…<p>Representative images are of untreated MRC5-V1/YFP-Topo III cells or cells treated for 48 h with 2 µM telomestatin. A, Topo III detected by fluorescence of YFP-tagged Topo III (green) and PML detected by immunofluorescence (red). …”