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49701
Synthesis and Spectroscopic Investigation of a Series of Push–Pull Boron Dipyrromethenes (BODIPYs)
Published 2017“…A series of push–pull BODIPYs bearing multiple electron-donating and electron-acceptor groups were synthesized regioselectively from 2,3,5,6,8-pentachloro-BODIPY, and characterized by NMR spectroscopy, HRMS, and X-ray crystallography. …”
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49702
Image_5_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif
Published 2022“…Treatment of NOD mice with sorafenib significantly impeded the development of type 1 diabetes and ameliorated insulitis, which coincided with a specifically decreased accumulation of Th1 cell population in the pancreas but not in peripheral immune organs. …”
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49703
Image_3_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif
Published 2022“…Treatment of NOD mice with sorafenib significantly impeded the development of type 1 diabetes and ameliorated insulitis, which coincided with a specifically decreased accumulation of Th1 cell population in the pancreas but not in peripheral immune organs. …”
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49704
Psychophysical Evaluation of a Sanshool Derivative (Alkylamide) and the Elucidation of Mechanisms Subserving Tingle
Published 2010“…Application at longer ISIs (∼30 min) resulted in a sensation of decreased intensity consistent with self-desensitization. …”
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49705
Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen
Published 2009“…</p><h3>Conclusion/Significance</h3><p>Among the novel hits was PALD (KIAA1274, paladin), a previously uncharacterized protein that when overexpressed led to inhibition of insulin's ability to down regulate a FOXO1A-driven reporter gene, reduced upstream insulin-stimulated AKT phosphorylation, and decreased insulin receptor (IR) abundance. …”
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49706
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49707
Interstitial Fluid Flow and Drug Delivery in Vascularized Tumors: A Computational Model
Published 2013“…We find that an increased vascular wall conductivity together with a reduction of lymph function leads to increased tumor IFP, but also that the latter does not necessarily imply a decreased extravasation rate: Generally the IF flow rate is positively correlated with the various conductivities in the system. …”
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49708
Predicting improved protein conformations with a temporal deep recurrent neural network
Published 2018“…In this study, we propose a deep recurrent network model, called DeepTrajectory, that is able to identify these improved conformational states, with high precision, from a variety of different MD based sampling protocols. …”
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49709
Differentially expressed genes playing a role in sex hormone biosynthesis and metabolism.
Published 2017“…<p>Sex hormone biosynthesis and metabolism is accomplished by a complex cascade involving hormones and enzymes of the hypothalamic-pituitary-gonadal axis, the vitamin D synthesis and the pineal gland hormone melatonin. …”
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49710
Evaluation of a Powered Ankle-Foot Prosthesis during Slope Ascent Gait
Published 2016“…We sought to determine the effect of active ankle plantarflexion and push-off power provided by a powered prosthetic ankle-foot (PWR) on lower extremity compensations in individuals with unilateral TTA as they walked up a slope. …”
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49711
Table_2_Behavior Change in Urban Mammals: A Systematic Review.XLSX
Published 2020“…<p>As cities expand to accommodate a growing human population, their impacts to natural ecosystems and the wildlife residing within them increase. …”
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49712
Temporal Proteomic and Phosphoproteomic Analysis of EV-A71-Infected Human Cells
Published 2022“…We found that Myc proto-oncogene protein level decreased significantly, benefiting EV-A71 replication. …”
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49713
Table_3_Behavior Change in Urban Mammals: A Systematic Review.DOCX
Published 2020“…<p>As cities expand to accommodate a growing human population, their impacts to natural ecosystems and the wildlife residing within them increase. …”
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49714
Data Sheet 1_Prognostic impact of miR-17-5p and miR-20a-5p in NSCLC diverge in subgroups according to lymph node status.docx
Published 2025“…Overexpression of miR-20a-5p led to decreased proliferation in one of two investigated cell lines and, like miR-17-5p, increased invasion.…”
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49715
Data score sheets of the Walker (2008) and Phenice (1969) traits from Pretoria Bone Collection and Raymond A. Dart Collection of Modern Human Skeletons to estimate sex from skeleta...
Published 2024“…<p dir="ltr">Forensic anthropologists are often required to establish a biological profile from skeletal remains, which includes the estimation of biological sex. …”
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49716
Data_Sheet_1_Effect of a High Fat Diet vs. High Carbohydrate Diets With Different Glycemic Indices on Metabolic Parameters in Male Endurance Athletes: A Pilot Trial.docx
Published 2022“…Additionally, body composition and perceptual responses to the diets [visual analog scale (VAS)] were measured. A significance level of α = 0.05 was considered. …”
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49717
A case study to identify the hindrances to widespread adoption of electric vehicles in qatar
Published 2020“…The adoption of electric vehicles (EVs) have proven to be a crucial factor to decreasing the emission of greenhouse gases (GHG) into the atmosphere. …”
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49718
Table1_Effect of dexmedetomidine on liver transplantation: a meta-analysis.DOCX
Published 2023“…Compared with the control group, the DEX group had a reduced warm ischemia time (MD-4.39; 95% CI-6.74−2.05), improved postoperative liver (peak aspartate transferase: MD-75.77, 95% CI-112.81−38.73; peak alanine transferase: MD-133.51, 95% CI-235.57−31.45) and renal function (peak creatinine: MD-8.35, 95% CI-14.89−1.80), and a reduced risk of moderate-to-extreme liver ischemia-reperfusion injury (OR 0.28, 95% CI 0.14-0.60). …”
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49719
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49720
The Costs and Benefits of Employing an Adult with Autism Spectrum Disorder: A Systematic Review
Published 2015“…</p><p>Results and Conclusion</p><p>Enhancing the opportunities for adults with ASD to join the workforce is beneficial from a societal perspective, not only from an inclusiveness viewpoint, but also from a strict economic standpoint. …”