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59021
Genetically engineered suicide gene in mesenchymal stem cells using a Tet-On system for anaplastic thyroid cancer
Published 2017“…A bystander effect also be demonstrated in co-cultures with MSC-TK/Fluc cells and CAL62/Rluc; both the Rluc activity and the Fluc activity were significantly decreased following GCV treatment. …”
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59022
Table1_Comparative Efficacy of Pharmacological Therapies for Low Back Pain: A Bayesian Network Analysis.docx
Published 2022“…<p>Low back pain (LBP) is a common problem, but the efficacy of pharmacological therapies remains controversial. …”
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59023
Declining geomorphic diversity and potential adaptive management opportunities on a highly regulated reach of the Bighorn River, Montana
Published 2025“…We document how the Bighorn River's anabranching morphology responded to flow regulation and a near cessation of sediment supply. Geomorphic diversity drastically decreased since 1939 and the Bighorn River abandoned numerous side channels. …”
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59024
A New Experimental Device for Transapical Access of the Aortic and Mitral Valves as well as the Aorta in its Various Segments
Published 2017“…<div><p>Abstract Objective: To present the results of a new experimental device developed to facilitate the transapical access in endovascular treatment of structural heart diseases. …”
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59025
Image 1_Intraplacental choriocarcinoma and spontaneous fetomaternal hemorrhage: Uncovering diagnostic clues in a challenging case.jpeg
Published 2025“…Data from these cases were combined to evaluate clinical characteristics, diagnostic approaches, treatment options, and outcomes.</p>Results<p>A 31-year-old woman presented with decreased fetal movements at 34 weeks and 2 days of gestation. …”
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59026
(A) Lung weight of control and JTE-522 treated rats injected with RCN-9 (group 1, 10
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats"</p><p>BMC Cancer 2005;5():26-26.…”
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59027
Table_1_A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise.XLSX
Published 2020“…<p>Objectives: To investigate diet-exercise interactions related to bone markers in elite endurance athletes after a 3.5-week ketogenic low-carbohydrate, high-fat (LCHF) diet and subsequent restoration of carbohydrate (CHO) feeding.…”
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59028
<b>The </b><b>declining </b><b>diel vertical migrators in a warming shelf sea</b>
Published 2025“…<p dir="ltr">Over three years of observing vertical migration of organisms in a warming shelf sea, our results indicate a decreasing tendency for organisms to migrate at twilight. …”
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59029
Severe vegetation degradation associated with different disturbance types in a poorly managed urban recreation destination in Iran
Published 2021“…This study examined the impact of different kinds of recreational activities on plant communities in a highly visited park in Mashhad, Iran. Vegetation in the park was sampled along 41 random 10-m transects with different human disturbances (trails, dirt roads, campsites) and undisturbed communities. …”
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59030
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59031
DataSheet1_Cascades of Periodic Solutions in a Neural Circuit With Delays and Slow-Fast Dynamics.PDF
Published 2021“…We show that such states accumulate in similar bifurcation cascades with decreasing values of the lateral input strength. We report a parameter-dependent scaling constant for the ratio of widths of successive regions in the cascades, which generalises across cycle skipping and swapping states. …”
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59032
A Tightly Controlled Conditional Knockdown System Using the <em>Tol2</em> Transposon-Mediated Technique
Published 2012“…However, the application of this method to analyses in later stages of brain development or in the adult brain is still difficult because the amount of injected plasmids in a cell decreases along with development due to dilution by cell proliferation and the degradation of the plasmids. …”
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59033
During cortical development there is a switch from exocytosis dominated by spontaneous exocytosis to asynchronous and synchronous vesicle exocytosis.
Published 2015“…<b>C</b>: By implementing the mRNA expression levels as ratios for SVE, aEVE and sEVE, a period of rapid learning is observed early in development during which SVE decreases and aEVE and sEVE increase. …”
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59034
RNA-seq analysis of <i>sig-7(RNAi)</i> embryos reveals a global transcription defect.
Published 2016“…<p>RNA-seq was performed on RNA purified from <i>sig-7(RNAi)</i> and L4440 control RNAi embryos and the profiles compared. A) Volcano plot of normalized RNA-seq results showing the number of genes exhibiting significantly decreased (1549) and increased (362) RNA abundance in <i>sig-7(RNAi)</i> compared to L4440 (>2-fold differences with q value < 0.05). …”
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59035
0A ~ P amplitude and frequency control cell fate decision between biofilm matrix production and sporulation.
Published 2025“…., mild starvation), the amplitude of the 0A ~ P signal increases, its frequency decreases, and biofilm matrix production is activated stochastically in some cells (green line). …”
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59036
A Prospective Study of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Type 1 Gaucher Disease Patients
Published 2013“…In order to evaluate the role of BM stem cells in GD pathophysiology, we prospectively analyzed BM-MSCs and HSPCs properties in a series of 10 patients with type 1 GD. GBA activity was decreased in all tested cell subtypes. …”
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59037
Generation of a Tex signature from the T cell atlas and its network-based rescoring for target prioritization with Patrimony.
Published 2024“…<p><b>(A)</b> Venn diagram of Tex scRNA-seq signatures. …”
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59038
Evolution of Extra-Nigral Damage Predicts Behavioural Deficits in a Rat Proteasome Inhibitor Model of Parkinson's Disease
Published 2011“…<div><p>Establishing the neurological basis of behavioural dysfunction is key to provide a better understanding of Parkinson's disease (PD) and facilitate development of effective novel therapies. …”
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59039
Image_1_HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease.jpeg
Published 2023“…Introduction<p>In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine. …”
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59040
Alien Plants Introduced by Different Pathways Differ in Invasion Success: Unintentional Introductions as a Threat to Natural Areas
Published 2011“…The proportion of naturalized and invasive species among all introductions delivered by a particular pathway decreases with a decreasing level of direct assistance from humans associated with that pathway, from release and escape to contaminant and stowaway. …”