A fast <i>in situ</i> hybridization chain reaction method in <i>Drosophila</i> embryos and ovaries by Kyohei Mikami (4237810)

“…Ethylene carbonate was added to the hybridization buffer to facilitate the hybridization reaction, and a modified short hairpin DNA was used in the amplification reaction; these modifications decreased the RNA staining time from 3 days to 1 day. …”

Redox, acetyl CoA and cholesterol levels in G6PD^deficient mice hearts. by Dhwajbahadur K. Rawat (304142)

“…<p>Metabolites produced from NADPH-dependent reaction were estimated in wild-type and G6PD^deficient mice hearts. A and B: G6PD deficiency decreased reduced glutathione-to-oxidized glutathione (GSH-to-GSSG; A) ratios determined by colorimetric assay and superoxide (O2−; B) estimated by lucigenin (5 µM) chemiluminescence method. …”

Mortality in Children Aged 0-9 Years: A Nationwide Cohort Study from Three Nordic Countries by Yongfu Yu (477682)

“…</p><p>Methods and Findings</p><p>The cohort study included all children born in Denmark from 1973 to 2008 (n = 2,433,758), Sweden from 1973 to 2006 (n = 3,400,212), and a random sample of 89.3% of children born in Finland from 1987 to 2007 (n = 1,272,083). …”

Supplementary Material for: Construction of a hybrid vaccine based on Der f 35-derived peptides with reduced allergenicity by Hu H. (4145581)

“…The IgE-ELISA revealed a significant reduction in IgE-binding activity to the vaccine when compared to wild-type Der f 35 (p < 0.0001), the decreased allergenicity were further confirmed by IgE-Western blot, inhibition ELISA and BAT, respectively. …”

Correlation of <i>DAPK1</i> methylation and the risk of gastrointestinal cancer: A systematic review and meta-analysis by Wenzheng Yuan (838940)

“…Also, the heterogeneity decreased most significantly in the subgroup of studies that had a sample size of less than 60 cases. …”

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition by Naping Hu (2614399)

“…The aim of this study was to investigate whether Hydroxysafflor yellow A (HSYA) can preserve renal function by inhibiting the progression of renal fibrosis and the potential mechanisms.…”

K-pairwise model for a the same group of <i>N</i> = 100 cells shown in Figure 1. by Gašper Tkačik (213054)

“…<p>The neurons are again sorted in the order of decreasing firing rates. (<b>A</b>) Pairwise interactions, , and the comparison with the interactions of the pairwise model, (<b>B</b>). …”

Impact of Temperature Variation on the Biological Traits and Lifecycle of Spodoptera exigua(Lepidoptera: Noctuidae): A Meta-Analysis Approach by 洪桦 张 (19650790)

“…<p dir="ltr"><i>Spodoptera exigua</i> is a significant pest of crops, but its ability to adapt to new climates remains poorly understood. …”

Per recruit egg production as a function of harvest mortality rate for the long-lived species (red curve). by Arnaud Grüss (220918)

“…Consequently, when lifetime egg production is a decreasing, convex function of harvest mortality, adult movement leads to lower egg production immediately after reserve implementation than larval dispersal. …”

NKG2A⁺ NK cells were expanded during AIM, but not during the incubation period. by Samantha K. Dunmire (510177)

“…<p>(A) Percentage and number of NK cells that are CD56^bright (immature) decreases during the first 50 days after symptom onset. …”

Effect of rehabilitation on biologic and transcriptomic responses after hospital-acquired deconditioning: a prospective longitudinal feasibility study by Odette Laneuville (10020226)

“…Within-subject changes in gene expression were analyzed using a gene ontology hierarchical clustering to identify common biological terms. …”

image_4_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

image_7_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer by Arundhati Jana (157555)

“…<div><p>Background</p><p>Colorectal cancer remains a deadly cancer due to metastatic disease. To understand the molecular mechanisms of metastasis in colon cancer, we investigated whether the copper chaperone antioxidant-1 (Atox1) protein plays a role in this process. …”

image_2_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Raw data for Figure 3B: Mesoangioblasts and HIDEMs suppress T cell proliferation in a dose dependent manner by Ou Li (101542)

Table_2_Efficacy and Safety of Faecal Microbiota Transplantation for Acute Pancreatitis: A Randomised, Controlled Study.DOC by Ling Ding (302098)

“…Eligible participants were randomly assigned to receive faecal transplant (n = 30) or normal saline (n = 30) via a nasoduodenal tube once and then again 2 days later. …”

ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer by Tom G. Keulers (4804599)

“…Besides oxygen, delivery of glucose was hampered in hypoxic regions <i>in vivo</i>, which increases the reliance of cells on other carbon sources (e.g., L-glutamine). We observed decreased intracellular L-glutamine levels in ATG12-deficient cells during hypoxia and increased cell killing after L-glutamine depletion, indicating a central role for ATG12 in maintaining L-glutamine homeostasis. …”

Data_Sheet_1_Altered Vascular Adaptations to Pregnancy in a Rat Model of Advanced Maternal Age.pdf by Mazhar Pasha (11197767)

“…We previously demonstrated vascular dysfunction and abnormal pregnancy outcomes in a rat model of advanced maternal age. However, vascular adaptations to pregnancy in aging were not studied. …”

Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study by Yuko Minami (7861412)

“…In the Cox model, ever-drinking was associated with a decreased risk of all-cause (HR: 0.75; 95% CI: 0.54–1.05) and breast cancer-specific death (HR: 0.68; 95% CI: 0.46–0.99). …”