Arthrospira (Spirulina) Platensis Can Be Considered as a Probiotic Alternative to Reduce Heat Stress in Laying Japanese Quails by H Hajati (10447036)

“…<div><p>ABSTRACT This study was conducted to investigate the effects of Arthrospira platensis (Spirulina platensis, SP) on feed intake, feed conversion ratio, egg weight, hen day egg production, intestinal microflora, heat stress biomarkers, and HSP70 gene expression in laying Japanese quails (Coturnix coturnix japonica) suffering heat stress condition. A total of 250 female quails were allocated to 5 treatments, 5 replicates and 10 birds in each replicate in a completely randomized design. …”

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx by Giacomo Brisca (10963929)

“…Background<p>Neuromuscular disorders (NMDs) represent a complex group requiring specialized care, often straddling the needs between general pediatric wards and Intensive Care Units (ICUs). …”

Video_1_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.MP4 by Ravikanth Velagapudi (7880072)

“…<p>Postoperative delirium is a frequent and debilitating complication, especially amongst high risk procedures such as orthopedic surgery, and its pathogenesis remains unclear. …”

Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake by Kyong-Hoon Ahn (423974)

“…Taken together, these results show that Hsp60 may serve as a negative regulator in N-SMase2-induced dopamine re-uptake by decreasing the protein level of N-SMase2.…”

<b>SIRT6 Is a Key Regulator of Pancreatic β-cell Survival and Function during Aging</b> by Jimin Park (1396840)

“…<b> </b>Our data suggest that SIRT6 is a critical anti-aging factor in pancreatic β cells and it can be a potential therapeutic target.…”

Increased Apoptosis after Autoimmune Regulator Expression in Epithelial Cells Revealed by a Combined Quantitative Proteomics Approach by Nuria Colomé (1863916)

“…The results showed increased levels of several chaperones, (HSC70, HSP27 and tubulin-specific chaperone A) in AIRE-expressing cells, while various cytoskeleton interacting proteins, that is, transgelin, caldesmon, tropomyosin alpha-1 chain, myosin regulatory light polypeptide 9, and myosin-9, were decreased. …”

siRNA screen for DNA repair factors associated with HIV infection revealed a role for the BER pathway. by Amy S. Espeseth (226760)

“…<i>(C)</i> Diagram of the BER pathway based on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017612#pone.0017612-Sancar1" target="_blank">[13]</a>. siRNAs targeting BER factors colored yellow decreased HIV infectivity by at least 40%, siRNAs targeting BER factors colored red increased HIV infectivity by at least 2×. siRNAs targeted BER factors colored blue had no effect on HIV infection.…”

DataSheet1_A Metabolic Profiling Study of Realgar-Induced Acute Kidney Injury in Mice.xls by Sheng Zhang (111330)

“…Principal component analysis (PCA), correlation analysis, and pathway analysis were used to detect the nephrotoxic effects of Realgar. Body weight decreased significantly in the 2.0 g/kg group, and the kidney weight index also showed a dose-dependent increase in Realgar. …”

Image_1_Auranofin coated catheters inhibit bacterial and fungal biofilms in a murine subcutaneous model.tif by LewisOscar Felix (13135377)

“…To reduce microbial adhesion, murine and human catheters were coated with polyurethane and auranofin using a dip coating method and compared to non-coated materials. …”

<b>Altered molecular regulation of TUG is a central feature of insulin resistant human adipose tissue</b> by Jordan W. Strober (22613649)

“…<p dir="ltr">White adipose tissue (WAT) insulin resistance (IR) is a central feature of the metabolic syndrome, yet data regarding defects in WAT insulin signaling in humans with IR is limited. …”

File S1 - AFLPs and Mitochondrial Haplotypes Reveal Local Adaptation to Extreme Thermal Environments in a Freshwater Gastropod by María Quintela (122518)

“…Colors in the diagrams follow a decreasing thermal trend (i.e. warmest populations are depicted in the darkest colors). …”

Image_1_Characterization of a de novo GABBR2 variant linked to autism spectrum disorder.JPEG by Noa Bielopolski (17437437)

“…Functional assays confirmed the MD predictions, as evidenced by increased constitutive activity and enhanced potency of GABA for GABBR2 p.Arg212Gln, and a decreased constitutive activity with a loss of GABA potency for GABBR2 p.Arg212Trp. …”

Ectopic Pregnancy as a Model to Identify Endometrial Genes and Signaling Pathways Important in Decidualization and Regulated by Local Trophoblast by W. Colin Duncan (209189)

“…There were no differences in <em>PRL</em> or <em>IGFBP1</em> expression in the decidualization-matched samples but a marked reduction (<em>P</em><0.001) in the non-decidualized samples. …”

Motor Network Plasticity and Low-Frequency Oscillations Abnormalities in Patients with Brain Gliomas: A Functional MRI Study by Chen Niu (343397)

“…All subjects performed a motor task to help identify individual motor activity in the bilateral primary motor cortex (PMC) and supplementary motor area (SMA). …”

Table_2_A Comprehensive Analysis of Population Differences in LRRK2 Variant Distribution in Parkinson's Disease.DOCX by Li Shu (5767922)

“…</p><p>Results: In the absence of obvious heterogeneities and publication biases among the included studies, we concluded that A419V, R1441C/G/H, R1628P, G2019S, and G2385R were associated with increased PD risk (p: 0.001, 0.0004, < 0.00001, < 0.00001, and < 0.00001, respectively), while R1398H was associated with decreased risk (p: < 0.00001). …”

Image2_The Efficacy and Safety of Brolucizumab for the Treatment of nAMD: A Systematic Review and Meta-Analysis.JPEG by Junlan Chuan (6648617)

“…</p><p>Results: A total of six RCTs with 3,574 participants were finally involved in this meta-analysis. …”

Table_1_A Comprehensive Analysis of Population Differences in LRRK2 Variant Distribution in Parkinson's Disease.DOCX by Li Shu (5767922)

“…</p><p>Results: In the absence of obvious heterogeneities and publication biases among the included studies, we concluded that A419V, R1441C/G/H, R1628P, G2019S, and G2385R were associated with increased PD risk (p: 0.001, 0.0004, < 0.00001, < 0.00001, and < 0.00001, respectively), while R1398H was associated with decreased risk (p: < 0.00001). …”

Table_1_Trends and Disparities in the Incidence of Intraocular Foreign Bodies 1990–2019: A Global Analysis.DOCX by Minjie Yuan (11568097)

“…Furthermore, while ASIR of IOFBs was high in the young population aged 15–49 years, we observed a significant increase in the number of IOFB incident cases in older adults when compared to other age groups. …”

The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia by Chao Shen (520343)

“…<div><p>MicroRNA-22 (miR-22) is emerging as a critical regulator in organ development and various cancers. …”

The Role of Histone Methylation and H2A.Z Occupancy during Rapid Activation of Ethylene Responsive Genes by Yongfeng Hu (187019)

“…However, the mutation of genes encoding H2A.Z and LHP1 attenuated and enhanced respectively the induction of target genes and altered H3K4me3. …”