<em>GCN5</em> Is a Positive Regulator of Origins of DNA Replication in <em>Saccharomyces cerevisiae</em> by Maria Claudia Espinosa (253850)

“…Here we show that the deletion of <em>GCN5</em> decreases the stability of mini-chromosomes; that the tethering of <em>Gcn5p</em> to a crippled origin of replication stimulates its activity; that high dosage of <em>GCN5</em> suppresses conditional phenotypes caused by mutant alleles of <em>bona fide</em> replication factors, <em>orc2-1</em>, <em>orc5-1</em> and <em>mcm5-461</em>. …”

Supplementary Material for: Successful Management of Post-Thymectomy Pure Red Cell Aplasia with Rituximab: A Case Report by Abdulgayoom M. (17726475)

“…Abstract Background: Pure red cell aplasia (PRCA) is a rare cause of anemia characterized by decreased red blood cell production, often associated with thymomas. …”

Supplementary information files for: Silica-silicon composites for near-infrared reflection: A comprehensive computational and experimental study by Kevin Conley (5986953)

“…Further, the calculated spectra predict a reddish tan compact with improved reflectance can be obtained by decreasing the average particle size or broadening the standard deviation. …”

Characterization of multi-scale amplitude of motility data by wavelet analysis from a representative subject with major depression. by Premananda Indic (320555)

“…<p>(<b>a</b>) Raw data in arbitrary units (a.u), with amplitudes of rhythms detected at three time-scales. …”

ToxB- and ToxA-induced regulation of genes involved in photosynthesis and the effect of ToxB on thylakoid proteins. by Iovanna Pandelova (154443)

“…<p>(A) Differences between control and toxin treatment presented as: line graphs for fold change (left axis) and bar graphs for the number of genes (right axis) that are significantly up- (lines above zero and grey bars) or down-regulated (lines below zero and white bars) at indicated hours post infiltration (hpi) (bottom axis). …”

Proposed model of RIG-I as a pivotal regulator of the inflammasome response against IAV in lung epithelial cells. by Julien Pothlichet (229745)

“…<p>1) Upon IAV infection, RIG-I senses viral genomic RNA and triggers a type I interferon response through a MAVS/TRIM25/Riplet-dependent pathway. 2) Binding of type I interferon to IFNAR1 initiates a positive feedback loop that stimulates RIG-I/TLR3/NLRP3 expression. 3) This upregulation is necessary for RIG-I- and NLRP3-inflammasome assembly, cleavage of caspase 1 and, ultimately, mature IL-1β secretion. 4) RIG-I upregulation stimulates type I IFN and constitutes an additional positive feedback loop. 5) 1918 NS1 could form more prominent complexes with RIG-I than USSR NS1, and/or target other cellular component(s) involved in type I IFN signaling, to result in a stronger inhibition of RIG-I-dependent type I interferon response by NS1 from the highly virulent pandemic 1918 influenza strain. 1918 NS1 protein-mediated inhibition of the type I IFN response consequently decreases IL-1β secretion.…”

Disrupted resting-state brain functional network in methamphetamine abusers: A brain source space study by EEG by Hassan Khajehpour (8115884)

Total recovery of visual acuity in a pediatric patient with compressive optic neuropathy secondary to sphenoid sinus mucocele by Facundo Urbinati (14061626)

“…<div><p>ABSTRACT We present an unusual case of a 13-year-old male pediatric patient with a diagnosis of sphenoid sinus mucocele. …”

Morphological evolution of <em>Stephanodiscus</em> (Bacillariophyta) in Lake Biwa from a 300 ka fossil record by Megumi Saito-Kato (2843789)

“…<p>A series of intermittent changes in <em>Stephanodiscus</em> (Bacillariophyta) valve morphology was observed in sediment core materials collected from Lake Biwa, Japan. …”

Sensitivity analysis (2): Varying initial O₂ in the headspace (()) within a high range. by Junaid Hassan (655726)

“…The cumulated N₂ reached stable plateaus at nearly the same time for all the runs (Panel E), despite the fact that the time taken to deplete O₂ below decreased with increasing (Panel A). Thus, once denitrification was initiated, the rates increased with increasing initial due to an increasing population of oxygen-grown cells (Panels B–D). …”

Table_1_Recovery of a hypolipidemic polysaccharide from artificially cultivated Sanghuangporus vaninii with an effective method.DOC by Zuo-fa Zhang (14421900)

“…The purified polysaccharide (PFSV-2) was found to be a hetero-polysaccharide with an average molecular weight of 20.377 kDa. …”

Efficacy and safety of corticosteroid regimens for the treatment of hospitalized COVID-19 patients: a meta-analysis: Supplementary data by Fangwen Zhou (9034640)

Evolutionarily Repurposed Networks Reveal the Well-Known Antifungal Drug Thiabendazole to Be a Novel Vascular Disrupting Agent by Hye Ji Cha (140719)

“…<div><p>Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. …”

Disrupted Small-World Brain Networks in Moderate Alzheimer's Disease: A Resting-State fMRI Study by Xiaohu Zhao (175664)

“…<div><p>The small-world organization has been hypothesized to reflect a balance between local processing and global integration in the human brain. …”

Pediculectomy and fenestration for spinal cord decompression of the lumbar spine of a bush dog (Speothos venaticus) - case report by P.V.T. Marinho (5383583)

“…<div><p>ABSTRACT A captive adult male bush dog (Speothos venaticus) was referred to our Veterinary Medical Teaching Hospital from a local zoo due to a two-week history of progressive hind limb gait impairment and ataxia, non-responsive to clinical management. …”

Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor by LiMei Wang (5651041)

“…<div><p>The multifunctional signaling protein p75 neurotrophin receptor (p75^NTR) is a central regulator and major contributor to the highly invasive nature of malignant gliomas. …”

Data_Sheet_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.PDF by Ran Fang (533948)

“…<p>Pyoderma gangrenosum (PG) is a rare, destructive inflammatory skin disease of which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. …”

Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties by Keigo Hirai (12095443)

“…Through IAM chromatography analysis and in vivo brain penetration assay of the HyTs, we discovered a brain-permeable HyT. Our results and mechanistic analysis indicate that conversion of protein degraders into HyTs could be a useful approach to improve their drug-like properties.…”

Table_1_A Novel Biallelic STING1 Gene Variant Causing SAVI in Two Siblings.doc by Malak Ali Alghamdi (9960260)

“…Exome sequencing revealed a novel homozygous NM_198282.3: c.841C>T; p.(Arg281Trp) variant in exon 7 of the STING1 gene. …”

Cross-Linking Porcine Pericardium by 3,4-Dihydroxybenzaldehyde: A Novel Method to Improve the Biocompatibility of Bioprosthetic Valve by Binggang Wu (9925999)

“…In conclusion, the properties of bioprosthetic valves could be effectively improved by processing valves with a DHBA-based cross-linking method.…”