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59421
Plant Hormone Salicylic Acid Produced by a Malaria Parasite Controls Host Immunity and Cerebral Malaria Outcome
Published 2015“…The mutant had a significantly decreased concentration of parasite-synthesized prostaglandin E<sub>2</sub>, which potentially modulates host immunity as an adaptive evolution of <i>Plasmodium</i> spp. …”
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59422
Table_1_Causal effects of potential risk factors on postpartum depression: a Mendelian randomization study.docx
Published 2023“…MR analysis showed that higher body mass index (BMI) (Benjamini and Hochberg (BH) corrected p = 0.05), major depression (MD) (BH corrected p = 5.04E-19), and schizophrenia (SCZ) (BH corrected p = 1.64E-05) were associated with the increased risk of PPD, whereas increased age at first birth (BH corrected p = 2.11E-04), older age at first sexual intercourse (BH corrected p = 3.02E-15), increased average total household income before tax (BH corrected p = 4.57E-02), and increased years of schooling (BH corrected p = 1.47E-11) led to a decreased probability of PPD. MVMR analysis suggested that MD (p = 3.25E-08) and older age at first birth (p = 8.18E-04) were still associated with an increased risk of PPD.…”
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59423
Table1_Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study.docx
Published 2024“…<p>Background: Sepsis, a global health challenge, necessitates a nuanced understanding of modifiable factors for effective prevention and intervention. …”
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59424
Image_1_Disentangling Environmental Effects on the Tree Species Abundance Distribution and Richness in a Subtropical Forest.TIFF
Published 2021“…<p>As a transitional vegetation type between evergreen broadleaved forest and deciduous broadleaved forest, evergreen-deciduous broadleaved mixed forest is composed of diverse plant species. …”
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59425
Table_1_eIF6 as a Promising Diagnostic and Prognostic Biomarker for Poorer Survival of Cutaneous Melanoma.xlsx
Published 2022“…Moreover, the decreased methylation level of keratin genes suggested a new potential regulation mode of eIF6.…”
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59426
DataSheet1_Development and validation of a pyroptosis-related genes signature for risk stratification in gliomas.docx
Published 2023“…<p>Background: Glioma is a highly heterogeneous disease, causing the prognostic prediction a challenge. …”
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59427
Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates
Published 2015“…<div><p>The importance of the organic cation transporter OCT2 in the renal excretion of cationic drugs raises the possibility of drug-drug interactions (DDIs) in which an inhibitor (perpetrator) drug decreases OCT2-dependent renal clearance of a victim (substrate) drug. …”
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59428
Image_2_Patterns of Immune Infiltration in HNC and Their Clinical Implications: A Gene Expression-Based Study.tif
Published 2019“…Each cancer subtype has a specific molecular classification and subtype-specific immune cell characterization.…”
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59429
Table_1_Patterns of Immune Infiltration in HNC and Their Clinical Implications: A Gene Expression-Based Study.DOCX
Published 2019“…Each cancer subtype has a specific molecular classification and subtype-specific immune cell characterization.…”
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59430
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59431
DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx
Published 2024“…Background<p>Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by persistent inflammatory cascades, with macrophage activation playing a pivotal role. Chitinase 1 (CHIT1), produced by activated macrophages, is a key player in this cascade. …”
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59432
Table_2_eIF6 as a Promising Diagnostic and Prognostic Biomarker for Poorer Survival of Cutaneous Melanoma.xlsx
Published 2022“…Moreover, the decreased methylation level of keratin genes suggested a new potential regulation mode of eIF6.…”
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59433
Table_4_The m6A methylation landscape, molecular characterization and clinical relevance in prostate adenocarcinoma.docx
Published 2023“…Finally, the immune characteristics analysis showed that compared with the low-risk group, the levels of M1 and M2 macrophages in the high-risk group significantly increased, while the levels of mast cells resting and T cells CD4 memory resting significantly decreased.</p>Conclusions<p>This study provides novel findings that can further the understanding of the role of m6A methylation during the progression of PCa, which may facilitate the invention of targeted therapeutic drugs.…”
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59434
Perioperative Intravenous Acetaminophen Attenuates Lipid Peroxidation in Adults Undergoing Cardiopulmonary Bypass: A Randomized Clinical Trial
Published 2015“…The effect of acetaminophen on lipid peroxidation in adults has not been studied. This was a pilot study designed to test the hypothesis that acetaminophen attenuates lipid peroxidation in adults undergoing CPB and to generate data for a clinical trial aimed to reduce acute kidney injury following cardiac surgery.…”
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59435
Image_2_Disentangling Environmental Effects on the Tree Species Abundance Distribution and Richness in a Subtropical Forest.TIFF
Published 2021“…<p>As a transitional vegetation type between evergreen broadleaved forest and deciduous broadleaved forest, evergreen-deciduous broadleaved mixed forest is composed of diverse plant species. …”
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59436
Data_Sheet_1_A Bibliometric Analysis of 100 Most-Cited Articles on Corneal Cross-Linking.PDF
Published 2022“…A bibliometric analysis of the top 100-cited articles was conducted in the current study. …”
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59437
Image1_The Effects of Rhubarb for the Treatment of Diabetic Nephropathy in Animals: A Systematic Review and Meta-analysis.pdf
Published 2021“…<p>Background: Rhubarb, also known as Da Huang, is a traditional Chinese medicine, and it was often used as a laxative in the past. …”
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59438
Table_2_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx
Published 2024“…Background<p>Despite establishing an association between gut microbiota and spondyloarthritis (SpA) subtypes, the causal relationship between them remains unclear.…”
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59439
Table_3_In Vivo Efficacy and Toxicity of Curcumin Nanoparticles in Breast Cancer Treatment: A Systematic Review.docx
Published 2021“…<p>Breast cancer is one of the most prevalent types of malignant tumors in the world, resulting in a high incidence of death. The development of new molecules and technologies aiming to apply more effective and safer therapy strategies has been intensively explored to overcome this situation. …”
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59440
Data_Sheet_1_Elasmobranch Responses to Experimental Warming, Acidification, and Oxygen Loss—A Meta-Analysis.zip
Published 2021“…Overexploitation has been driving a worldwide decline in elasmobranch populations, and rapid environmental change, triggered by anthropogenic activities, may further test this group's resilience. …”