Image_2_Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.tiff by Matteo Trudu (13758211)

“…Altogether, our results reveal a novel direct pro-survival effect of arginine deprivation on myeloma cells, with potential therapeutic implications.…”

Video_2_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.MP4 by Daisuke Hasegawa (239088)

“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”

DataSheet_1_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.docx by Florence Jeny (4978466)

“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”

Table1_Efficacy and safety of antibiotic agents in the treatment of rosacea: a systemic network meta-analysis.docx by Wenqin Xiao (586854)

“…The heterogeneity and inconsistency between the trials were low, with a low risk of bias of all trials. Oral doxycycline 40 mg, minocycline 100 mg, and minocycline 40 mg, as well as topical ivermectin and metronidazole 0.75%, were effective in treating papules and pustules, thereby decreasing IGA in rosacea. …”

Image_2_Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.tiff by Matteo Trudu (13758211)

“…Altogether, our results reveal a novel direct pro-survival effect of arginine deprivation on myeloma cells, with potential therapeutic implications.…”

Image15_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.JPEG by Weizhong Xiao (14847373)

“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”

Impact of the Lab-Score on Antibiotic Prescription Rate in Children with Fever without Source: A Randomized Controlled Trial by Laurence Lacroix (673501)

“…</p><p>Trial Registration</p><p>ClinicalTrials.gov <a href="http://clinicaltrials.gov/show/NCT02179398" target="_blank">NCT02179398</a></p></div>…”

The reliability and validity of the Swedish translation of the Vertigo Symptom Scale – short form in a cohort with acute vestibular syndrome by Solmaz Surano (20699511)

“…The discriminative ability was excellent for the acute VSS–SF and VSS–V (AUC 0.98 and 0.99), and acceptable for VSS–A (AUC 0.77). After six weeks, discriminative ability decreased but remained above 0.5. …”

Image_1_Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside.TIF by Ilia Y. Bozo (10095142)

“…This advanced combined therapy medicinal product had no cytotoxic effects in vitro, slightly decreased bone marrow mesenchymal stromal cell (MSC) doubling time, and was characterized by a prolonged level of gene construct delivery in vivo in a luciferase bioimaging assay. …”

Data_Sheet_1_Neuroinflammation in early, late and recovery stages in a progressive parkinsonism model in rats.PDF by Debora M. G. Cunha (13432077)

“…Repeated treatment with a low dose of reserpine—inhibitor of VMAT2—has been proposed as a progressive pharmacological model of PD. …”

DataSheet3_Influence of Menisci on Tibiofemoral Contact Mechanics in Human Knees: A Systematic Review.pdf by Matthias Sukopp (3987356)

“…Studies were identified through a systematic literature search in Cochrane, PubMed and Web of Science databases. …”

Image7_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.TIF by Weizhong Xiao (14847373)

“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”

Role of tick Fatty acid synthase (FAS) in response to <i>A</i>. <i>phagocytophilum</i> infection. by Nieves Ayllón (420744)

“…The JAK/STAT pathway genes were down-regulated in nymphs, up-regulated in adult female midguts and not affected by bacterial infection in adult female salivary glands, suggesting that <i>A</i>. <i>phagocytophilum</i> infection decreased immunity in nymphs while inhibited cell apoptosis in midgut cells to facilitate and establish infection. …”

Image5_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.TIF by Weizhong Xiao (14847373)

“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”

Image3_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.TIF by Weizhong Xiao (14847373)

“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”

Image_5_Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.tiff by Matteo Trudu (13758211)

“…Altogether, our results reveal a novel direct pro-survival effect of arginine deprivation on myeloma cells, with potential therapeutic implications.…”

Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights by Daniel Nettersheim (2866097)

“…GCTs are highly susceptible to interference with the epigenetic landscape; therefore, this study focuses on screening of drugs against epigenetic factors as a treatment option for GCTs.</p><p><br></p> <p>Results:</p><p>We present seven different epigenetic inhibitors efficiently decreasing cell viability in GCT cell lines including cisplatin-resistant subclones at low concentrations by targeting epigenetic modifiers and interactors, like histone deacetylases (Quisinostat), histone demethylases (JIB-04), histone methyltransferases (Chaetocin), epigenetic readers (MZ-1, LP99) and polycomb-repressive complexes (PRT4165, GSK343). …”

Video1_A versatile, bioengineered skin reconstruction device designed for use in austere environments.MP4 by Joachim G. S. Veit (16077143)

“…As proof of concept for such a device, silk fibroin and an antioxidant hyaluronic acid derivative were chosen as primary constituents. …”

Image_4_Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.tiff by Matteo Trudu (13758211)

“…Altogether, our results reveal a novel direct pro-survival effect of arginine deprivation on myeloma cells, with potential therapeutic implications.…”

Data_Sheet_1_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.DOCX by Daisuke Hasegawa (239088)

“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”