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59861
Table_1_Fatty acids and risk of dilated cardiomyopathy: A two-sample Mendelian randomization study.xlsx
Published 2023“…As a probable metabolite of oleic acid, fatty acid (18:1)-OH has a suggestive association with a lower risk of DCM (OR = 0.402, 95%CI: 0.167–0.966, P = 0.041). …”
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59862
Table_7_The m6A methylation landscape, molecular characterization and clinical relevance in prostate adenocarcinoma.docx
Published 2023“…Finally, the immune characteristics analysis showed that compared with the low-risk group, the levels of M1 and M2 macrophages in the high-risk group significantly increased, while the levels of mast cells resting and T cells CD4 memory resting significantly decreased.</p>Conclusions<p>This study provides novel findings that can further the understanding of the role of m6A methylation during the progression of PCa, which may facilitate the invention of targeted therapeutic drugs.…”
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59863
Table2_Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.XLSX
Published 2022“…<p>ORAL squamous cell carcinoma (OSCC) is a malignant tumor with the highest incidence among tumors involving the oral cavity maxillofacial region, and is notorious for its high recurrence and metastasis potential. …”
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59864
Supplementary Material for: Possible Association of <i>SLC22A2</i> Polymorphisms with Aspirin-Intolerant Asthma
Published 2011“…Recently, SLC22A2-mediated uptake inhibition by several nonsteroidal anti-inflammatory drugs and decreased SLC22A2 transport activity by its genetic variants have been elucidated in asthma. …”
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59865
Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX
Published 2024“…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …”
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59866
Table3_Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.XLSX
Published 2022“…<p>ORAL squamous cell carcinoma (OSCC) is a malignant tumor with the highest incidence among tumors involving the oral cavity maxillofacial region, and is notorious for its high recurrence and metastasis potential. …”
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59867
Effectiveness of community-based peer support for mothers to improve their breastfeeding practices: A systematic review and meta-analysis
Published 2017“…<div><p>Breastfeeding is associated with reduced mortality in children aged less than 5 years. We conducted a systematic review and meta-analysis (registered as PROSPERO 2015: CRD42015019105) to examine the effectiveness of community-based peer support for mothers on their breastfeeding practices as compared to mothers who have not received such a support.…”
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59868
<i>Toxoplasma gondii</i> serine-protease inhibitor-1: A new adjuvant candidate for asthma therapy
Published 2017“…Once the asthmatic phenotype was achieved, mice were intranasally treated with rTgPI-1 alone or with a mixture of rTgPI-1 and ovalbumin (OVA). A week later mice were given a secondary aerosol challenge. …”
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59869
The Effect of Complete Integration of HIV and TB Services on Time to Initiation of Antiretroviral Therapy: A Before-After Study
Published 2012“…We present a model of full TB/HIV integration and estimate its effect on time to initiation of ART.…”
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59870
Table_1_The epithelial transcriptome and mucosal microbiota are altered for goats fed with a low-protein diet.DOCX
Published 2023“…Herein, this study was performed to examine the changes in relative abundance of ruminal microbiota and host ruminal mucosal transcriptome profiles in response to a LP diet.</p>Methods<p>A total of twenty-four female Xiangdong balck goats with similar weight (20.64 ± 2.40 kg) and age (8 ± 0.3 months) were randomly assigned into two groups, LP (5.52% crude protein containing diet) and CON (10.77% crude protein containing diet) groups. …”
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59871
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59872
Addition of Alanyl-Glutamine to Dialysis Fluid Restores Peritoneal Cellular Stress Responses – A First-In-Man Trial
Published 2016“…Further effects were glutamine-like metabolomic changes and increased <i>ex-vivo</i> LPS-stimulated cytokine release from healthy donor peripheral blood monocytes. In patients with a history of peritonitis (5 of 20), AlaGln supplementation decreased dialysate interleukin-8 levels. …”
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59873
<i>fahd-1(tm5005) C</i>. <i>elegans</i> have a locomotion deficit.
Published 2015“…<p>(A) 4-day old wild-type and <i>fahd-1(tm5005)</i> animals were placed on an empty NGM plate (without bacterial lawn) and the number of body bends was counted for one minute. …”
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59874
CD39 and immune regulation in a chronic helminth infection: The puzzling case of <i>Mansonella ozzardi</i>
Published 2018“…Surprisingly, CD39 blocking with a neutralizing antibody suppressed antigen-driven lymphoproliferation <i>in vitro</i>, while decreasing inflammatory cytokine responses, in Fil+ and Fil- individuals. …”
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59875
Nonacethrene Unchained: A Cascade to Chiral Contorted Conjugated Hydrocarbon with Two sp<sup>3</sup>‑Defects
Published 2022“…Compared to peropyrene, the absorption and emission of hypercethrene are slightly red-shifted on account of extended π-conjugation and the fluorescence quantum yield of 0.45 is decreased by a factor of ∼2. Enantiomerically enriched hypercethrene displays circularly polarized luminescence with a brightness value of 8.3 M<sup>–1</sup> cm<sup>–1</sup>. …”
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59876
A novel prospective isolation of murine fetal liver progenitors to study <i>in utero</i> hematopoietic defects
Published 2018“…Expression of <i>P2-hCD4</i> in the FL immunophenotypic Megakaryocyte-Erythroid Progenitor (MEP) and Common Myeloid Progenitor (CMP) compartments corresponded to increased granulocytic/monocytic/megakaryocytic and decreased erythroid specification. Moreover, <i>Runx1-P2-hCD4</i> expression correlated with several endogenous cell surface markers’ expression, including CD31 and CD45, providing a new strategy for prospective identification of highly purified fetal myeloid progenitors in transgenic mouse models. …”
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59877
Imaging Long-Term Fate of Intramyocardially Implanted Mesenchymal Stem Cells in a Porcine Myocardial Infarction Model
Published 2011“…Repetitive [<sup>18</sup>F]FEAU PET/CT revealed a biphasic pattern of sr39HSV1-tk-MSC dynamics; cell proliferation peaked at 33–35 days after injection, in periinfarct regions and the major cardiac lymphatic vessels and lymph nodes. …”
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59878
Plant Hormone Salicylic Acid Produced by a Malaria Parasite Controls Host Immunity and Cerebral Malaria Outcome
Published 2015“…The mutant had a significantly decreased concentration of parasite-synthesized prostaglandin E<sub>2</sub>, which potentially modulates host immunity as an adaptive evolution of <i>Plasmodium</i> spp. …”
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59879
Table_1_Causal effects of potential risk factors on postpartum depression: a Mendelian randomization study.docx
Published 2023“…MR analysis showed that higher body mass index (BMI) (Benjamini and Hochberg (BH) corrected p = 0.05), major depression (MD) (BH corrected p = 5.04E-19), and schizophrenia (SCZ) (BH corrected p = 1.64E-05) were associated with the increased risk of PPD, whereas increased age at first birth (BH corrected p = 2.11E-04), older age at first sexual intercourse (BH corrected p = 3.02E-15), increased average total household income before tax (BH corrected p = 4.57E-02), and increased years of schooling (BH corrected p = 1.47E-11) led to a decreased probability of PPD. MVMR analysis suggested that MD (p = 3.25E-08) and older age at first birth (p = 8.18E-04) were still associated with an increased risk of PPD.…”
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59880
Table1_Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study.docx
Published 2024“…<p>Background: Sepsis, a global health challenge, necessitates a nuanced understanding of modifiable factors for effective prevention and intervention. …”