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59961
Data_Sheet_1_Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.docx
Published 2019“…Microglia responded to the obesogenic conditions by a shift of substrate utilization with decreased glutamate and glucose metabolism in the active period of the animals, and an overall increase of lipid metabolism, as indicated by gene expression evaluation. …”
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59962
Image10_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.JPEG
Published 2023“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”
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59963
DataSheet_1_Association of genetically determined chronotype with circulating testosterone: a Mendelian randomization study.xlsx
Published 2024“…<p>Low testosterone levels in men have been linked to decreased physical and mental function, as well as a reduced quality of life. …”
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59964
Bacterial and fungal infections: a frequent and deadly complication among critically ill acute liver failure patients
Published 2023“…The presence of infection at ICU admission (<i>p</i> = .04), but not ICU-acquired infection, was associated with decreased survival.</p> <p>The prevalence of infection is high in ALF patients which is associated with a higher risk of death. …”
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59965
Image11_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.JPEG
Published 2023“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”
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59966
Image4_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.TIF
Published 2023“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”
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59967
DataSheet_1_Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy.pdf
Published 2020“…Background<p>Epilepsy is a serious health problem worldwide. Despite the introduction of new antiepileptic drugs (AEDs) almost 30% of these patients have drug-resistant forms of the disease (DRE), with a significant increase in morbi-mortality.…”
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59968
Defects in the GINS complex increase the instability of repetitive sequences <i>via</i> a recombination-dependent mechanism
Published 2019“…These processes require sequence homology search which in case of a repeated DNA tract may result in misalignment leading to its expansion or contraction.…”
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59969
A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice
Published 2015“…While other studies have identified a role for miRNAs in obesity, we here present a unique model that allows for the study of processes involved in reversing obesity. …”
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59970
Image_2_Exacerbation of Nanoparticle-Induced Acute Pulmonary Inflammation in a Mouse Model of Metabolic Syndrome.tiff
Published 2020“…To examine this hypothesis, mice were fed either a control diet or a high-fat western diet (HFWD) for 14-weeks. …”
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59971
Image14_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.JPEG
Published 2023“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”
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59972
Video_2_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.MP4
Published 2021“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”
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59973
Table_1_Incident comorbidities in patients with chronic hypoparathyroidism after thyroidectomy: a multicenter nationwide study.docx
Published 2024“…</p>Methods<p>We performed a multicenter, retrospective cohort study including patients with chronic postsurgical hypoparathyroidism lasting ≥3 years with at least a follow-up visit between January 1, 2022 and September 15, 2023 (group H). …”
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59974
Schematic Representation of Calmodulin Binding to a CaMKII Subunit, Intersubunit Phosphorylation Steps, and the Protein Signaling Cascade
Published 2013“…<div><p>(A–E) Show calcium/calmodulin binding and phosphorylation reactions of a ring of six functionally coupled subunits of the CaMKII holoenzyme. …”
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59975
Image9_Circulating adipokine concentrations and the risk of venous thromboembolism: A Mendelian randomization and mediation analysis.TIF
Published 2023“…<p>Background: Previous observational studies have suggested that circulating adipokine concentrations are related to a greater risk of venous thromboembolism (VTE). …”
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59976
Image_2_Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside.TIF
Published 2021“…This advanced combined therapy medicinal product had no cytotoxic effects in vitro, slightly decreased bone marrow mesenchymal stromal cell (MSC) doubling time, and was characterized by a prolonged level of gene construct delivery in vivo in a luciferase bioimaging assay. …”
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59977
Table4_Causal association between tea intake and risk for gout: a Mendelian randomization study.XLSX
Published 2023“…</p><p>Conclusion: Our MR analysis suggest a causal relationship between genetically predicted tea intake and a decreased risk of gout. …”
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59978
Data_Sheet_1_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.DOCX
Published 2021“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”
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59979
Image_1_Exacerbation of Nanoparticle-Induced Acute Pulmonary Inflammation in a Mouse Model of Metabolic Syndrome.tiff
Published 2020“…To examine this hypothesis, mice were fed either a control diet or a high-fat western diet (HFWD) for 14-weeks. …”
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59980
Image_2_Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.tiff
Published 2022“…Altogether, our results reveal a novel direct pro-survival effect of arginine deprivation on myeloma cells, with potential therapeutic implications.…”