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9781
Ube3a negatively regulates Tkv protein levels in S2 cells.
Published 2016“…(E) A decrease in Tkv protein level was observed in Ube3a-overexpressing S2 cells; the effect was abolished by treatment with the 26S proteasome inhibitor MG132. …”
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9782
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9783
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9784
Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic <i>Escherichia coli</i> K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier
Published 2016“…<div><p>Background</p><p>NF-κB activation, pathogen invasion, polymorphonuclear leukocytes (PMN) transmigration (PMNT) across the blood-brain barrier (BBB) are the pathogenic triad hallmark features of bacterial meningitis, but the mechanisms underlying these events remain largely unknown. Vimentin, which is a novel NF-κB regulator, is the primary receptor for the major <i>Escherichia coli</i> K1 virulence factor IbeA that contributes to the pathogenesis of neonatal bacterial sepsis and meningitis (NSM). …”
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9785
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9786
Wnt5a Regulates the Assembly of Human Adipose Derived Stromal Vascular Fraction-Derived Microvasculatures
Published 2016“…We exposed hSVF cells to a battery of angiogenesis inhibitors and found that the pan-Wnt inhibitor IWP2 produced the most significant hSVF-EC networking decrease (~25%). …”
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9787
Wnt mediates hSVF vascular self-assembly.
Published 2016“…<p><b>(A)</b> The CCK-8 cell cytotoxicity assay demonstrated that IWP2 concentrations ≤ 25μM were not cytotoxic, whereas 50μM was cytotoxic (***<i>p</i> ≤ 0.001). …”
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9788
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
Published 2016“…CRP GRS<sub><i>GWAS</i></sub> showed a statistically significant protective relationship of a 10% genetically elevated CRP level with the risk of schizophrenia (odds ratio [OR] 0.86 [95% CI 0.79–0.94]; <i>p <</i> 0.001). …”
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9789
Feasibility of brief intensive exposure therapy for PTSD patients with childhood sexual abuse: a brief clinical report
Published 2022“…The treatment included 5 working days with individual sessions (in total 30 h of treatment) provided by a team of four therapists. The PTSD symptoms of all patients decreased substantially and the effect sizes were large (Cohen's d resp. 1.5 [pre–post], 2.4 [pre-FU1 month], and 2.3 [pre-FU3 months]). …”
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9790
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9791
Overexpression of Atp13a2 protects cells from manganese cytotoxicity.
Published 2019“…Graph is representative of three independent experiments and data is shown as mean ±SDM. Cells expressing Atp13a2 show a significant decrease in cell death compared to normal HeLa cells after exposure to MnCl<sub>2</sub>. …”
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9792
Culture reduces hSVF vascularization potential.
Published 2016“…<b>(C)</b> The average total hSVF EC length at day 5 was quantified and normalized to measurements of P1, day 5. Significant decreases in total hSVF EC length are seen by day 5 as a function of increasing passage (***<i>p</i> ≤ 0.001). …”
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9793
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9794
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9795
HDAC1 knockdown significantly increases RGS10 expression while HDAC1 overexpression decreases RGS10 expression in chemoresistant ovarian cancer cells.
Published 2014“…Graphed data shows the average of three independent experiments, with error bars denoting standard error of the mean (SEM). Significance was calculated with a Student's t test **p<0.005. …”
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9796
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9797
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9798
Sociodemographic characteristics of participants.
Published 2023“…As expected in this pilot trial, there were no significant differences between conditions in percent heavy drinking/drug using days or receipt of substance use services and large individual differences in outcomes. For example, receipt of substance use services decreased by a mean of 0.05 times/day from the baseline to the 6-month time period in the control condition (range -1.00 to +0.55) and increased by a mean of 0.06 times/day in the intervention condition (range -0.13 to +0.89). …”
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9799
The CONSORT diagram.
Published 2023“…As expected in this pilot trial, there were no significant differences between conditions in percent heavy drinking/drug using days or receipt of substance use services and large individual differences in outcomes. For example, receipt of substance use services decreased by a mean of 0.05 times/day from the baseline to the 6-month time period in the control condition (range -1.00 to +0.55) and increased by a mean of 0.06 times/day in the intervention condition (range -0.13 to +0.89). …”
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9800
The intervention process.
Published 2023“…As expected in this pilot trial, there were no significant differences between conditions in percent heavy drinking/drug using days or receipt of substance use services and large individual differences in outcomes. For example, receipt of substance use services decreased by a mean of 0.05 times/day from the baseline to the 6-month time period in the control condition (range -1.00 to +0.55) and increased by a mean of 0.06 times/day in the intervention condition (range -0.13 to +0.89). …”