Pretreatment of Huh-7.5.1 cells with PF-429242 results in a robust decrease in intracellular DENV-2 RNA and post-treatment of DENV-2 infected Huh-7.5.1 cells with PF-429242 impairs the assembly and/or release of infectious virus particles. by Anastasia Hyrina (3860455)

Study design. by Tibor M. Szikszay (14439419)

A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects by Katherine Stewart (848894)

“…This results in decreased GAP activity for the prototypical Rho-family members, RhoA and Rac1, likely due to disrupted ordering of the Rho binding surface. …”

Rape-related symptoms in adolescents: short- and long-term outcome after cognitive behavior group therapy by Iva Bicanic (14339079)

“…</p> <p>Repeated measures analysis showed a significant and large decrease in symptoms of PTS, anxiety, depression, anger, dissociation, sexual concerns, and behavior problems directly after treatment, which maintained at 12 months follow-up. …”

datasheet1_Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model.pdf by Laura Dhondt (10032890)

“…Clearances of iohexol and amikacin increased with on average 15 and 14%, although large interindividual variability was observed. This led to decreased systemic exposure to amikacin, which was manifested as decrease in area under the plasma concentration-time curve from time 0 h to infinity from 34,807 to 30,804 ng.h/mL. …”

Fig 1 - by Emily Baker (3492485)

Pull down assay of RhoA. by Frank Roloff (695802)

Subjects: “…pain reliever Ibuprofen decreases RhoA…”

Rho kinase (ROCK) inhibitors promote neurite elongation of human model neurons. by Frank Roloff (695802)

Subjects: “…pain reliever Ibuprofen decreases RhoA…”

RhoA and Rho kinase inhibitors promote initiation of neurites. by Frank Roloff (695802)

Subjects: “…pain reliever Ibuprofen decreases RhoA…”

Ibuprofen increased neurite length of human model neurons. by Frank Roloff (695802)

Subjects: “…pain reliever Ibuprofen decreases RhoA…”

A schematic representation of mathematical model. by Wenli Cai (324636)

miR-148a inhibited DNMT1expression. by Ping Wang (42415)

“…(B) DNMT1 expression was decreased in PFFs of overexpressing miRNA-148a. DNMT3a expression has no difference in PFFs of overexpressing miRNA-148a compared with control group. …”

Association between rs3212172 and metabolic variables. by Valérie Marcil (5127431)

“…<p>A negative coefficient suggests decreasing value of the marker for every additional copy of the SNP. …”

MiR-10a-5p expression was reduced and miR-10a-5p overexpression was correlated with longer OS in melanoma. by Haijun Zhu (533051)

“…<p><b>(A)</b> Eight DEMs were identified based on the overlapped analysis of melanoma miRNAs in the TCGA-SKCM between early-stage melanoma tissues, advanced stage tissues dataset and OS-correlated miRNAs. …”

Epigenetic adaptation of the placental serotonin transporter gene (<i>SLC6A4</i>) to gestational diabetes mellitus by Sofia Blazevic (4173319)

“…<div><p>We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern of the fetal serotonin transporter gene (<i>SLC6A4</i>), and examined the functional relevance of DNA methylation for regulation of the <i>SLC6A4</i> expression in the human placenta. …”

Scale-free distribution of the number of male sexual partners among MSM in Beijing, China. by Jie Lou (535356)

Comparison (<i>P</i> values) between the raw and enzymatically pre-digested test substrates (↑ increase or ↓ decrease when compared to the microbial fermentation of the raw test su... by Nadine Paßlack (1806478)

“…<p>Comparison (<i>P</i> values) between the raw and enzymatically pre-digested test substrates (↑ increase or ↓ decrease when compared to the microbial fermentation of the raw test substrate; → no difference between the microbial fermentation of the raw and enzymatically pre-digested test substrate), for means see Tables <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0262536#pone.0262536.t004" target="_blank">4</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0262536#pone.0262536.t005" target="_blank">5</a>.…”

ELISA analysis revealed a significant decrease in SP (A & B) and CGRP (C & D) protein levels in the corneas and tear fluid of mice treated with 0.5% bupivacaine (BUP) every alternate day for 15 days (administered via subconjunctival injection (SCI) alone or in combination with topical (TOP) application) compared to PBS-treated controls. by Ananya Datta (19932144)

Mass Spectrometry Experiment 2 and 3: Comparison of Vpu WT and mutants. by Charlotte A. Stoneham (10819125)

Table 1 - What does heritability of Alzheimer’s disease represent? by Emily Baker (3492485)