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linear decrease » linear increase (Expand Search)
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Data_Sheet_1_Mesenchymal Stromal Cells Promote Retinal Vascular Repair by Modulating Sema3E and IL-17A in a Model of Ischemic Retinopathy.docx
Published 2021“…Mesenchymal stromal cells (MSCs) have potent pro-angiogenic and anti-inflammatory properties associated with tissue repair and regeneration, and in this regard exert protection to neurons in ischemic and degenerative conditions; however, the exact mechanisms underlying these functions remain largely unknown. Class III Semaphorins (A–G) are particularly implicated in regulating neural blood supply (as well as neurogenesis) by suppressing angiogenesis and affecting myeloid cell function; this is the case for distinct neuropillin-activating Sema3A as well as PlexinD1-activating Sema3E; but during IR the former Sema3A increases while Sema3E decreases. …”
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Blood phenylalanine test results (mmol/l) recorded in participants of the study.
Published 2022Subjects: -
10735
Validation of ALDH1A3 as target of miR-187.
Published 2015“…C) Luciferase reporter assay performed with firefly luciferase under control of the ALDH1A3 3′ UTR confirm the inhibition of ALDH1A3 mRNA expression (20% decrease of luciferase signal) upon miR-187 re-introduction. …”
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10736
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A Conserved Transcriptional Signature of Delayed Aging and Reduced Disease Vulnerability Is Partially Mediated by SIRT3
Published 2015“…The inverse of this transcriptional signature is detected with consumption of a high fat diet, obesity and metabolic disease, and is reversed in response to interventions that decrease disease risk. …”
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C9orf72 and SMCR8 form a stable protein complex.
Published 2016“…Immunoblot analysis of SMCR8 KO HAP1 cell lysates shows a decrease in C9orf72 levels compared with control HAP1 cells. …”
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10740