A low-noise silicon nitride nanopore device on a polymer substrate by Wook Choi (5540693)

“…Compared to the Si-substrate-based device, the dielectric noise was greatly reduced and the root-mean-square noise level was decreased from 146.7 to 5.4 pA. …”

Onset of nilotinib resistance in K562 and K562-Dox cells coincides with ABCB1 overexpression; ABCB1 levels decrease upon continued high dose nilotinib exposure. by Laura N. Eadie (3044079)

Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1) by Natalia Mast (737085)

“…Second, transcriptional regulation of the brain cholesterol biosynthesis <i>via</i> sterol regulatory element binding transcription factors is not significantly activated in the <i>Cyp46a1</i>^<i>-/-</i> brain to explain a compensatory decrease in cholesterol biosynthesis. …”

The influence of H₂O₂ on <i>P</i>. <i>berghei</i> infection in <i>A</i>. <i>stephensi</i>. by Li Gao (131516)

Structure diagram of the test load: 1-Pressure loading unit; 2—Buffer bar; 3—Strain gauge A2; 4—Transmission bar; 5—Rock specimen; 6—Support; 7—Strain gauge A1; 8—Incident bar; 9—H... by Chun Wang (337817)

Effect of cumulative gas during incubation durations of microencapsulated lemongrass and mangosteen peel (MELM) levels. by Rittikeard Prachumchai (18771149)

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

PMNs derived from either GF mice or mice treated with oral antibiotics have significantly decreased bactericidal activities against <i>P</i>. <i>aeruginosa</i> and altered transcri... by Abirami Kugadas (3131940)

Model A: Logistic structural model. by Abigail A. Lee (19935335)

“…<p>Latent variables concerning logistical factors and covariates were combined into a structural model. SEM was used to determine which factors impact parental intent to vaccinate their children against HPV as well as HPV vaccination hesitancy. …”

Lipid droplets transiently increase in size during early stages of HSV-1 infection. by Kamal L. Nahas (13014698)

Cardiac adherent proliferating cells increase T regulatory cells, increase apoptotic CD4 and CD8 T cells, and decrease apoptotic T regulatory cells in Coxsackievirus B3-infected mi... by Kapka Miteva (192634)

Presentation_1_In vivo Dominant-Negative Effect of an SCN5A Brugada Syndrome Variant.PPTX by Nicolas Doisne (10891632)

“…</p>Methods<p>Due to the large size of SCN5A, a dual AAV vector strategy was used combining viral DNA recombination and trans-splicing. …”

Effect of squalene on hepatic gene expression in male wild-type mice. by Clara Gabás-Rivera (613994)

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 5 by Surjyadipta Bhattacharjee (3181674)

“…<p><b>Reactive oxygen species (ROS)-, IL-1β- or TNFα-stressed MG cells—involvement of NF-kB and miRNA-34a and the effects of NF-kB inhibitors or anti-miRNAs (AMs)–(A)</b> representative Western blot of TREM2 protein levels in variably stressed MG cells both in the presence and absence of NF-kB and AMs; miRNA-34a levels were determined using microfluidic miRNA array analysis in the same sample (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g001" target="_blank">Fig 1</a></b>); <b>(B)</b> note ROS-, IL-1β- or TNFα-induced increases in miRNA-34a and TREM2 protein decreases in the same sample; when present the antioxidants and/or NF-kB inhibitors PBN, CAY10512, CAPE or curcumin quenched this induction; see text for further details; similarly anti-miRNA-34a (AM-34a) but not 4 other AM species: AM-183 (or AM-9, AM-125b or AM-146a; data not shown) selectively lowered miRNA-34a levels while increasing TREM2 to 0.92 of control levels; N = 6; *<i>p<</i>0.05, **<i>p</i><0.01 (ANOVA); NS = not significant.…”

Effect of the experimental diets on somatic variables in male mice of the three experimental models. by Clara Gabás-Rivera (613994)

Effect of dietary squalene supplementation on plasma parameters in male wild-type mice. by Clara Gabás-Rivera (613994)

Effect of dietary squalene supplementation on plasma parameters in male <i>Apoa1</i>-deficient mice. by Clara Gabás-Rivera (613994)

The role of ULK1-11A/ATG13-4A unphosphorylatable mutant in cell cycle progression. by Zhiyuan Li (205620)