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13641
Plasma membrane localized KCa3.1 is decreased by DN Rab1 and Rab8, but not by Rab2 or Rab6.
Published 2014“…<p>HEK293 cells were co-transfected with BLAP-KCa3.1 and either WT, DA or DN Rabs 1, 2, 6 or 8 and plasma membrane localized KCa3.1 evaluated by specific biotinylation, streptavidin labeling and IB (see Methods). As shown in <b>A</b> and <b>C</b>, DN Rab8 (T22N) and two different DN Rab1s (N124I, S25N) decreased expression of plasma membrane KCa3.1. …”
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13642
Table1_Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy.docx
Published 2024“…</p>Results<p>16 patients discontinued their afterload-reducing drugs, resulting in a significant decrease in median LVOT gradient from 86.5 [60.5–109.3] mmHg to 61.5 [28.3–97.50] mmHg (p = 0.0004). …”
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13643
Table1_Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy.docx
Published 2024“…</p>Results<p>16 patients discontinued their afterload-reducing drugs, resulting in a significant decrease in median LVOT gradient from 86.5 [60.5–109.3] mmHg to 61.5 [28.3–97.50] mmHg (p = 0.0004). …”
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13644
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13645
CHIP Regulates AKT/FoxO/Bim Signaling in MCF7 and MCF10A Cells
Published 2013“…<div><p>A number of studies have shown that apoptosis resistance can be observed in multiple human tumors; however the detailed mechanism remains unclear. …”
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13646
Overexpression of GFP-Rab22a does not induce PrP<sup>Sc</sup> degradation.
Published 2009“…Note that NH<sub>4</sub>Cl does not affect Rab22a-induced decrease in PrP<sup>Sc</sup> levels (p = 0,083, t-test).…”
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13647
Dose response association of objective physical activity with mental health in a representative national sample of adults: A cross-sectional study
Published 2018“…For LPA, a more complex shape (monotonic and curvilinear) was found. …”
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13648
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13649
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13650
Interaction between MED19a and HaRxL44 is important for HaRxL44–induced MED19a degradation via proteasome.
Published 2013“…All the confocal pictures were taken with PMT 1 (494–541 nm) at Gain: 864 and PMT 2 (591–649 nm) at Gain: 844. Note the decrease in GFP-MED19a transformed cells in the presence of RFP-HaRxL44 in comparison with RFP alone or RFP-HaRxL44<sup>M</sup>.…”
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13651
Enzymes of the ubiquitin system affect A53T α-synuclein aggregation.
Published 2021“…(D) Electrochemiluminescence immunoassay showed down-regulation of α-synuclein protein levels in doxycycline treated neurons in response to SCNA and USP9X siRNAs. Data are shown as mean±SEM. Data in (A) and (B) were analyzed by one-way ANOVA followed by Dunnett’s multiple comparison test (n = 2, m = 2). …”
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13652
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13653
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13654
Ligand-dependent nuclear import of AR was a prerequisite for PAN expression.
Published 2021“…<p>(A) Ligand treatment of DHT led to the increasing effect on PAN RNA in a dose-dependent manner. iSLK.219 cells were treated with DHT for 24 h prior to induction with doxcycline for another 24 h. …”
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13655
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13656
Effect of BM pretreatment on CYP3A at mRNA and functional activity level.
Published 2013“…BM treatment decreases the mRNA levels of CYP3A1and CYP3A2 in liver and intestine as assessed by real-time PCR as described in Materials and Methods. …”
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13657
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13658
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13659
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13660