Effects of S100A6 on CayBP/SIP-mediated β –catenin degradation. by Xiaoxuan Ning (334218)

“…<p>(A) Co-immunoprecipitation assay showed that truncated mutant CacyBP/SIPΔS100 bind both Skp1 and Siah1, suggesting S100A6 did not affect the formation of Siah1-CacyBP/SIP-Skp1 unbiquitin ligase complex. …”

Outcomes of critically ill COVID-19 patients boarding in the emergency department of a tertiary care center in a developing country: a retrospective cohort study by Zahran, Tharwat El

“…Our aim was to assess the ED LOS effect on mortality and morbidity, in addition to the predictors of in-hospital mortality, intubation, and complications of critically ill COVID-19 ED boarder patients. Methods: This was a retrospective cohort study, investigating 145 COVID-19-positive adult patients who were critically ill, required intensive care unit (ICU), and boarded in the ED of a tertiary care center in Lebanon. …”
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Data Sheet 1_Functional analysis of the Escherichia coli mrdA gene in melittin resistance.docx by Chong-Yi Zhao (20830733)

“…Objective<p>The aim of this study is to examine the functional role and resistance mechanisms of the Escherichia coli (E. coli) peptidoglycan transpeptidase gene, mrdA, in resistance to melittin.</p>Methods<p>The resistance of E. coli strains with either knockout or overexpression of the mrdA gene to melittin was initially assessed. …”

Raw data. by Reza Fadaei (3391958)

Subjects:

Effect of MDMA and HT on the a-wave and b-wave at 3 h and 24 h. by João Martins (5652628)

“…(A₂, B₂) Both MDMA and HT groups presented decreased time to peak values at 3 h time point when compared to Baseline ERG in both the a-wave and b-wave, while no significant differences were found at 24 h time point compared to Baseline ERG in all groups. *** p<0.001 MDMA group compared to Baseline ERG; ++ p<0.01, +++ p<0.001 HT group compared to Baseline ERG. …”

Transcript-Level In Silico Analysis of Alzheimer’s Disease-Related Gene Biomarkers and Their Evaluation with Bioactive Flavonoids to Explore Therapeutic Interactions by Muhammad Bilal Azmi (14519913)

“…The machine learning consensus classifier predictor categorized these transcript-level SNPs as the most deleterious variations, resulting in a large decrease in protein structural stability (ΔΔ<i>G</i> kcal/mol). …”

Evaluations of disease progression in G93A mice through Kaplan-Meier analysis. by Svitlana Garbuzova-Davis (81764)

“…<p>(<b>A</b>) Time elapsed until animals lost 15% of their maximum body weight. …”

Whole brain activation as a function of illness course. by Maggie M. Sweitzer (3167943)

Knockdown of transcription factors, SP1 and EGR1, attenuates miR-27a expression. by Bum-Yong Kang (350760)

“…HPAEC mRNA or proteins were then isolated. qRT-PCR was performed demonstrating decreases in SP1 (<b>A</b>) or EGR1 (<b>C</b>) mRNA levels following treatment with siRNA. …”

TG2 protects HEK 293A cells from hyperosmotic stress, independent of its localization and conformation. by Soner Gundemir (371977)

“…LDH release is significantly decreased in HEK 293A cells which express TG2 regardless of the conformation state or its subcellular localization (N = 5). …”

Soluble lytic transglycosylase SLT of <i>Francisella novicida</i> is involved in intracellular growth and immune suppression by Takemasa Nakamura (8190540)

“…However, the detailed mechanisms of immune suppression and intracellular growth are largely unknown. Here we developed a transposon mutant library to identify novel pathogenic factors of <i>F</i>. …”

Table_1_SLC4A11 and MFSD3 Gene Expression Changes in Deoxynivalenol Treated IPEC-J2 Cells.DOCX by Yafei Xu (2515528)

“…However, genes involved in regulating DON toxicity and the underlying molecular mechanisms remain largely unknown. This study explored the role of SLC4A11 and MFSD3 in alleviating DON toxicity and analyzed the DNA methylation changes of these two genes. …”

Lysine Mutation of the Claw-Arm-Like Loop Accelerates Catalysis by Cellobiohydrolases by Zhiyou Zong (7336904)

“…Searching for viable strategies to accelerate the catalytic cycle of glycoside hydrolase family 7 (GH7) cellobiohydrolase I (CBHI)the workhorse cellulose-degrading enzymes, we have performed a total of 12-μs molecular dynamics simulations on GH7 CBHI, which brought to light a new mechanism for cellobiose expulsion, coined “claw-arm” action. …”

A. Gene expression of <i>SFRP1</i> during ACS measured by mRNA expression microarray analysis.... by Árpád V. Patai (132272)

“…<p>SFRP1 protein expression gradually decreased during ACS. The epithelial SFRP1 expression showed a continuous decrease during ACS. …”

Immunocytochemistry on adhesive mesenchymal stem cells (MSCs) using Ki67 (A), collagen (Col) type II (B), vimentin (C) and p63 (D). by Sarah Broeckx (511044)

“…<p>Native MSCs were negative for p63 and positive for Ki67, Col II and vimentin, whereas chondrogenic induced MSCs were positive for p63, Col II and vimentin with a decreased signal for Ki67 (arrows = negative nuclei). …”

Supplementary Material for: Increased Quinolone-Resistant Mutations of gyrA and parC Genes after Pouchitis Treatment with Ciprofloxacin by Fukushima K. (4865416)

“…Most bacterial mutations that confer quinolone resistance are at Ser-83 and Asp-87 in the <i>gyrA</i> gene and Ser-80 and Glu-84 in the <i>parC</i> gene. …”

Subcellular localization of NS2 in assembly deficient mutants in NS5A protein. by Costin-Ioan Popescu (230609)

“…(<b>E</b>) Mutations in NS5A protein drastically decrease the number of cells presenting NS2 dotted structures. …”

TGF-β1 down-regulates the expression of CD300a and Eomes in Th1 cells. by Sriram Narayanan (364941)

“…<p>(A) Sorted naïve CD4 T cells were polarized under Th1 or Th17 conditions as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010636#s4" target="_blank">materials and methods</a>. …”

Data_Sheet_1_GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a.docx by Yuchen Pan (761233)

“…Inhibition of NF-κB p65 promoted JMJD3 binding to miR-146a promoter and decreased the tri-methylation level of H3K27, while the inhibition of JMJD3 did not affect the recruitment of NF-κB p65 to miR-146a promoter. …”

Data_Sheet_1_GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a.docx by Yuchen Pan (761233)

“…Inhibition of NF-κB p65 promoted JMJD3 binding to miR-146a promoter and decreased the tri-methylation level of H3K27, while the inhibition of JMJD3 did not affect the recruitment of NF-κB p65 to miR-146a promoter. …”