DataSheet1_The C-Terminal Domain of Y-Box Binding Protein 1 Exhibits Structure-Specific Binding to Poly(ADP-Ribose), Which Regulates PARP1 Activity.pdf by Konstantin N. Naumenko (12899003)

“…Moreover, YB-1 acts as an effective cofactor in the PAR synthesis catalyzed by the PARP1 point mutants that generate various PAR polymeric structures, namely, short hypo- or hyperbranched polymers. We showed that either a decrease in chain length or an increase in branching frequency of PAR affect its binding affinity for YB-1 and YB-1–mediated stimulation of PARP1 enzymatic activity. …”

Antimicrobial resistance rates in gram-positive bacteria do not drive glycopeptides use by Beryl Primrose Gladstone (606879)

“…Data on glycopeptides´ DID and resistance rates of target microorganisms in blood cultures were identified among 31 countries over a 19-year period. Glycopeptides use significantly increased (p<0·0001) while rates of MRSA BSIs decreased in majority of the countries (p<0·0001) and MRCoNS and VRE BSIs remained stable. …”

DataSheet_6_Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation.pdf by Yasuo Shimizu (3521666)

“…We concluded that MAIT cells played a crucial role in suppressing the cytokine-producing capacity of ILC2s and ILC2 proliferation, that ultimately led to decrease in the allergic airway inflammation.…”

Human papillomavirus type 18 E5 oncoprotein cooperates with E6 and E7 in promoting cell viability and invasion and in modulating the cellular redox state by Jimena Hochmann (8590539)

“…Additionally, we observed that cells expressing HPV-18 E5/E6/E7 exhibited a decrease in catalase activity and a significant augmentation of GSH and PRX1 levels relative to those of E5, E6/E7, and HaCaT cells. …”

Image_1_Interest of the BLAST paradigm and salivary markers for the evaluation of sleepiness in drivers.JPEG by Marine Thieux (13739065)

“…The main objective of this study was to explore new potential markers (neurocognitive, biological) to objectively assess sleepiness in drivers.</p>Methods<p>A total of 186 drivers (median age 44 years, range 20–74 years, 73% men, 14% obese) were included during a break at a highway service area, in the morning, while on the road for vacation. …”

Image 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.tif by Chengzhi Hou (20419865)

“…To the left of this inflection, each unit increase in ALI was associated with a 1.3% decrease in all-cause and cardiovascular mortality risk among MACCE patients. …”

Life course perspective of the SOEP-IS sample. by Philipp D. Koellinger (7726172)

“…<div><p>The German Socio-Economic Panel (SOEP) serves a global research community by providing representative annual longitudinal data of respondents living in private households in Germany. …”

Data_Sheet_1_Regional analysis of planting date and cultivar maturity recommendations that improve soybean oil yield and meal protein concentration.docx by Montserrat Salmerón (13966419)

“…Our results show that delayed planting date and later cultivar maturity reduced oil concentration, and this was partially associated with a decrease in temperature during the seed fill phase. …”

The Overexpression of Twinkle Helicase Ameliorates the Progression of Cardiac Fibrosis and Heart Failure in Pressure Overload Model in Mice by Atsushi Tanaka (40313)

“…These LV functional improvements were accompanied by a decrease in interstitial fibrosis (WT: 10.6±1.1% vs Tg: 3.0±0.6%). …”

Table1_Population pharmacokinetics and exposure–response analyses of SAF-189s in Chinese patients with ALK+/ROS1+ non-small cell lung cancer.docx by Yinhui Liu (284549)

“…</p>Results<p>The final PopPK model of SAF-189s was described by a one-compartment model with delayed first-order absorption and time-dependent elimination by allowing the clearance to decrease stepwise over time. …”

DataSheet_1_Smoothelin-Like Protein 1 Regulates Development and Metabolic Transformation of Skeletal Muscle in Hyperthyroidism.docx by Evelin Major (11522875)

“…Moreover, SMTNL1 expression showed a 6-fold decrease in the hyperthyroid samples and in T3-treated C2C12 cells. …”

Data_Sheet_1_Unraveling the functional instability of bacterial consortia in crude oil degradation via integrated co-occurrence networks.pdf by Ping Li (31981)

“…Through three successive transfer passages, G2-G4 consortia were established, resulting in a gradual decrease in TPH degradation to 23.14% at the same time. …”

Projected Impact of the Medicare Part D Senior Savings Model (SSM) on Diabetes-Related Health and Economic Outcomes among Insulin Users Covered by Medicare by Hui Shao (316404)

“…Costs were estimated from a health system perspective. </p> <p><strong>Results: </strong>Of 4.2 million eligible Medicare beneficiaries, 1.6 million (38.3%) would benefit from the policy, and out-of-pocket costs per year per beneficiary would decrease by 61% or $500 on average. …”

Successful Application of Adaptive Emotion Regulation Skills Predicts the Subsequent Reduction of Depressive Symptom Severity but neither the Reduction of Anxiety nor the Reduction... by Carolin M. Wirtz (647287)

“…An increase in successful skills application during treatment was associated with a decrease in DSS and GDS but not ASS. Finally, successful ER skills application predicted changes in subsequent DSS but neither changes in ASS nor changes in GDS.…”

Color description for heatmap. by Miao Qi (665154)

“…<div><p>Disparities in healthcare access and utilization associated with demographic and socioeconomic status hinder advancement of health equity. Thus, we designed a novel equity-focused approach to quantify variations of healthcare access/utilization from the expectation in national target populations. …”

Data Sheet 4_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Comparison of relevant literature data. by Yingshuai Liu (2289718)

“…Among other things, solid-state SCR systems use solid ammonium as a precursor to ammonia, a change that reduces clogging problems due to icing and hydrolysis evaporation crystals at low temperatures compared to conventional aqueous urea solutions. …”

Image_2_Interest of the BLAST paradigm and salivary markers for the evaluation of sleepiness in drivers.JPEG by Marine Thieux (13739065)

“…The main objective of this study was to explore new potential markers (neurocognitive, biological) to objectively assess sleepiness in drivers.</p>Methods<p>A total of 186 drivers (median age 44 years, range 20–74 years, 73% men, 14% obese) were included during a break at a highway service area, in the morning, while on the road for vacation. …”

Table1_An immune and epithelial–mesenchymal transition-related risk model and immunotherapy strategy for grade II and III gliomas.DOCX by Wei Luo (80175)

“…Epithelial–mesenchymal transition (EMT)-related gene sets were significantly enriched in the high-risk group, and the epithelial–mesenchymal transition phenotype was associated with a decrease in CD8⁺ T cells and an increase in M2 macrophages. …”

S3 File - by Zi-Yun Yi (19859589)

“…In contrast, MII oocytes in the TSD group showed a decrease in the mtDNA copy number and a lower Δψm compared with the controls. …”