Transcription profile of MAdCAM-1 costimulated CD4⁺ T cells. by Sinmanus Vimonpatranon (14774429)

“…Each column represents one donor, each row represents a selected gene. Side bar indicates direction of gene modulation (green: decrease, red: increase) in T_RMs, as previously reported. (*: P < 0.05, **: P < 0.01, ***: P < 0.001 two-tailed t test).…”

Image_4_The Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic... by Berenice Márquez-Valadez (6590576)

“…These results indicate that H₁R blockade at E14–E16 favors the differentiation of dopaminergic neurons, but hampers their migration, leading to a decrease in dopaminergic innervation of the striatum in post-natal life.…”

Involvement of the Clock Gene <i>Rev-erb alpha</i> in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells by Elaine Vieira (174928)

“…<i>Rev-erb alpha</i> down-regulation by siRNA (60–70% inhibition) in alphaTC1-9 cells inhibited low-glucose induced glucagon secretion (p<0.05) and led to a decrease in key genes of the exocytotic machinery. …”

<i>n</i>P‑Collabs: Investigating Counterion-Mediated Bridges in the Multiply Phosphorylated Tau-R2 Repeat by Jules Marien (16699991)

“…Tau is an intrinsically disordered (IDP) microtubule-associated protein (MAP) that plays a key part in microtubule assembly and organization. …”

Table_3_Causal association of dietary factors with five common cancers: univariate and multivariate Mendelian randomization studies.docx by Lin Yang (45852)

“…Among the latter, one dietary habit showed a significant association with cancer even after FDR correction, indicating a potential causal relationship. …”

Image1_Dobutamine promotes the clearance of erythrocytes from the brain to cervical lymph nodes after subarachnoid hemorrhage in mice.TIF by Xue Wang (102830)

“…Dobutamine significantly promoted cerebrospinal fluid (CSF) drainage from the SAS to dCLNs and obviously reduced the RBC residue in mLVs, leading to a decrease in neuronal death and an improvement in cognitive function after SAH.…”

Waist-to-Height Ratio and Cardiovascular Risk Factors among Chinese Adults in Beijing by Li Cai (3899)

“…<div><p>Objectives</p><p>To examine whether waist-to-height ratio (WHtR) performed better than, body mass index (BMI) or waist circumference (WC) in relation to hypertension, diabetes, and dyslipidemia among Chinese adults in Beijing.</p><p>Methods</p><p>A total of 5720 adults (2371 men and 3349 nonpregnant women) aged 18 to 79 years were selected from the general population in a cross-sectional study. …”

Data_Sheet_1_The microbiota and metabolome dynamics and their interactions modulate solid-state fermentation process and enhance clean recycling of brewers’ spent grain.docx by Yueqin Xie (6282224)

“…Microbiologically, during the SSF, the group treated with MS inoculation exhibited an increase in the relative abundance of Leuconostoc (0.58%∼6.60%), Weissella (6.22%∼15.42%), Enterococcus (3.15%∼9.08%), Bacillus (17.63%∼31.29%), Lactobacillus (12.89%∼8.29%), Pseudoalteromonas (12.87%∼16.29%), and a decrease in the relative abundance of Acinetobacter (0.79%∼0.02%) and Enterobacteriaceae (0.78%∼0.24%). …”

Image_1_Differential effects of allopregnanolone and diazepam on social behavior through modulation of neural oscillation dynamics in basolateral amygdala and medial prefrontal cor... by Yosuke Yawata (5142431)

“…One hypothesis for the mechanism of depression involves a decrease in neuroactive steroids such as allopregnanolone, an endogenous positive allosteric modulator of the γ-aminobutyric acid–gated chloride channel (GABA_A) receptor. …”

Cobratoxin Alleviates Cancer-Induced Bone Pain in Rats via Inhibiting CaMKII Signaling Pathway after Acting on M4 Muscarinic Cholinergic Receptors by Longsheng Xu (4519405)

“…Cancer-induced bone pain (CIBP) is a common pain in clinics, which can reduce the quality of life and increase the mortality of patients, but the treatment of CIBP is limited. …”

Table_3_Dupilumab effectively and rapidly treats bullous pemphigoid by inhibiting the activities of multiple cell types.xlsx by Tianmeng Yan (16682754)

“…</p>Objective<p>We evaluated the efficiency and safety of dupilumab on BP treatment and explored a mode of drug action in depth.</p>Methods and results<p>A multicenter retrospective cohort included 20 BP patients who received dupilumab with or without systemic corticosteroid in dupilumab group, and 20 matched BP patients who received corticosteroid alone in conventional group. …”

Image_5_The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey.TIF by Guixin Zhang (795314)

“…Expression levels are relatively high in embryonic and early larval stages, gradually decrease, and are upregulated again in adults. Reductions of lecticans B and D are greater than those of A and C. …”

Table_1_Elevation of Serum Cytokine Profiles and Liver Metabolomic Normalization in Early Convalescence of COVID-19 Patients.DOCX by Yan Lou (1692556)

“…<p>Coronavirus disease 2019 (COVID-19) has become a global public health concern. We aimed to study the cytokine profile during the convalescent phase and its association with liver functions. …”

Image_1_Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages.jpeg by Shan Cao (5077988)

“…Dual-luciferase report assay and ChIP assay demonstrated that upon activation, FXR could directly bind to the promoter site of IL-6, leading to the decreased expression of IL-6. Thus, bile acids, especially CDCA, may operate to damp inflammation via FXR-mediated downregulation of IL-6 in mononuclear cells and provide a protective mechanism for CP patients.…”

Table1_Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.PDF by Tianye Li (9759056)

“…Most importantly, a marked decrease in nuclear β-catenin was observed in cells that received cisplatin treatment. …”

Isotopic and Geochemical Tracers for U(VI) Reduction and U Mobility at an in Situ Recovery U Mine by Anirban Basu (102199)

“…Postmining natural attenuation of residual U­(VI) at ISR mines is a potential remediation strategy. Detection and monitoring of naturally occurring reducing subsurface environments are important for successful implementation of this remediation scheme. …”

Table1.docx by Yan Liu (25061)

“…However, few studies stem from the perspective of whole transcriptome change in a fish brain and its response to long-term hypersaline stress. …”

Datasheet1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.pdf by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Presentation_1_Perivascular adipose tissue promotes vascular dysfunction in murine lupus.pptx by Hong Shi (177669)

“…In addition, expression of UCP1, a brown/beige adipose marker, was dramatically decreased, while CD45-positive leukocyte infiltration was increased, in PVAT from lupus mice. …”

Supplementary material for “Genetic insights into causal effects of serum lipids and lipid-lowering drug target genes on autoimmune thyroid disease” by Qinnan Zhang (18874897)

“…In cross-ancestry analysis, we found that CETP had a potential protective effect in GD (OR=0.43, 95%CI=0.21-0.86; P=0.018). …”