Data_Sheet_1_The global burden and temporal trend of cancer attributable to high body mass index: Estimates from the Global Burden of Disease Study 2019.docx by Xing Zhi (7401416)

“…In general, the burden of cancer attributable to high BMI was heavier in regions with higher SDI levels, whereas the increase slowed down or even showed a decreasing trend in the recent years. In contrast, in regions with lower SDI levels, although the baseline burden of cancer attributable to high BMI was relatively low, both the numbers and rates of deaths and DALYs showed a significantly increasing trend and may not stop increasing for a period of time. …”

Association of Ficolin-3 with Severity and Outcome of Chronic Heart Failure by Zoltán Prohászka (69659)

“…Low ficolin-3 levels were associated with increased complement activation product C3a and correspondingly decreased concentrations of complement factor C3.…”

DataSheet1_Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix.docx by Maxim S. Bril’kov (12409225)

“…This consolidation is incomplete for H3K4me3 binding to CW, which experiences a decrease in overall thermal stability on binding. …”

Lipid binding profiles of PDZ domains and differential effects of peptide ligands on PtdInsPs binding. by Ylva Ivarsson (279161)

“…<p><b>A</b>. Apparent PDZ-PtdInsPs affinities as determined by SPR equilibrium binding experiments between his-tagged PDZ domains and 5% PtdInsPs (DOPC liposomes). …”

Mechano-Responsive, Tough, and Antibacterial Zwitterionic Hydrogels with Controllable Drug Release for Wound Healing Applications by Kun Fang (619812)

“…Diacrylated Pluronic F127 micelles were used as a macro-cross-linker of the hydrogel and loaded with hydrophobic antimicrobial drugs. …”

Table 5_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc by Shujun Tan (20011518)

“…Similarly, the global ASMR declined from 13.81 in 1990 to 9.75 in 2021, with deaths decreasing from 883,082.06 to 603,605.62, representing a 31.65% reduction. …”

Table_1_Comparison of Clinical Efficacy and Safety of Metformin Sustained-Release Tablet (II) (Dulening) and Metformin Tablet (Glucophage) in Treatment of Type 2 Diabetes Mellitus.... by Li-xin Guo (11505091)

“…The Dulening and Glucophage groups showed comparable levels of decrease in HbA1c levels, FBG and weight loss after 12-week treatment (all p>0.05). …”

Data_Sheet_1_Effect of Lactobacillus fermentum ZS40 on the NF-κB signaling pathway in an azomethane-dextran sulfate sodium-induced colon cancer mouse model.ZIP by Jia Liu (41593)

“…The expression of inflammatory stimulators TNF-α and IL-1β in the probiotic treatment group decreased; the expression of key proteins IκBα and p65 in the NF-κB signaling pathway also decreased, resulting in a decrease in the expression of the target protein Cox-2. …”

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25 by Alexandra Rasnitsyn (4062982)

“…The present work reveals that FOXC1 is an important regulator of exocytosis and establishes a new link between FOXC1 and MYOC-associated glaucoma.…”

Comprehensive Analysis of Conditioned Media from Ovarian Cancer Cell Lines Identifies Novel Candidate Markers of Epithelial Ovarian Cancer by C. Geeth Gunawardana (2347063)

“…Ovarian cancer remains a deadly threat to women as the disease is often diagnosed in the late stages when the chance of survival is low. …”

Table_1_Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis.xls by Lingyan Zhu (519291)

“…<p>It remains poorly defined whether any human miRNAs play protective roles during HIV infection. Here, focusing on a unique cohort of HIV-infected former blood donors, we identified miR-31 (hsa-miR-31) by comparative miRNA profiling as the only miRNA inversely correlating with disease progression. …”

Image_3_CSF1R Inhibition Reduces Microglia Proliferation, Promotes Tissue Preservation and Improves Motor Recovery After Spinal Cord Injury.TIF by Yannick Nicolas Gerber (169700)

“…We first demonstrate that GW2580 treatment did not modify microglial response in non-injured spinal cords. Conversely, a strong decrease in proliferating microglia was observed following SCI. …”

Image_10_Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis.tif by Xiaoya Li (2022250)

“…Background<p>Non-alcoholic fatty liver disease (NAFLD), a metabolic disorder that develops from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), has become an epidemic of chronic liver dysfunction worldwide. …”

Data_Sheet_1_Influence of Heavy Metals (Ni, Cu, and Zn) on Nitro-Oxidative Stress Responses, Proteome Regulation and Allergen Production in Basil (Ocimum basilicum L.) Plants.doc by Egli C. Georgiadou (5483573)

“…Treatment with Cu led to increased concentration of the allergenic protein profilin, while increasing concentrations of Cu and Zn led to a decrease in the concentration of total proteins (likely due to proteolysis) and antioxidant capacity. …”

Pitfalls of DNA Quantification Using DNA-Binding Fluorescent Dyes and Suggested Solutions by Yuki Nakayama (365318)

“…This non-proportional decrease in Qubit values was dependent on a lower salt concentration, and over 1 mM NaCl in the DNA solution was required for the Qubit measurement. …”

Impact evaluation of Zika epidemic on congenital anomalies registration in Brazil: An interrupted time series analysis by Enny S. Paixão (7419110)

“…In the period “post-Zika event”, unlike the brain and eye group which showed a monthly decrease, the group without brain or eye malformations showed a slow but significant increase (relative to the pre-Zika trend) of 0.2/10,000 live births. …”

Mechano-Responsive, Tough, and Antibacterial Zwitterionic Hydrogels with Controllable Drug Release for Wound Healing Applications by Kun Fang (619812)

“…Diacrylated Pluronic F127 micelles were used as a macro-cross-linker of the hydrogel and loaded with hydrophobic antimicrobial drugs. …”

Table 1_Amiodarone treatment in cats: evaluation of indications, adverse effects, and survival outcomes.docx by Graham C. Rossi (20573861)

“…There was a decrease in serum concentration of alanine transaminase between pretreatment values and values measured during the early amiodarone treatment window, 1–90 days (n = 16; p = 0.034). …”

Table_1_IL-6 signaling drives self-renewal and alternative activation of adipose tissue macrophages.xlsx by Jan Ackermann (18067144)

“…</p>Results<p>Obese Il6ra^Δmyel mice exhibited no differences in insulin sensitivity or histological markers of AT inflammation. Notably, we found a reduction of ATMs expressing the mannose receptor 1 (CD206), as well as a decrease of the proliferation marker Ki67 in ATMs of Il6ra^Δmyel mice. …”

Comprehensive Analysis of Conditioned Media from Ovarian Cancer Cell Lines Identifies Novel Candidate Markers of Epithelial Ovarian Cancer by C. Geeth Gunawardana (2347063)

“…Ovarian cancer remains a deadly threat to women as the disease is often diagnosed in the late stages when the chance of survival is low. …”