Image2_Interleukin 9 mediates T follicular helper cell activation to promote antibody responses.jpeg by Taiki Sato (394623)

“…Accumulating evidence indicates a crucial role for interleukin-9 (IL-9) in the formation of germinal centers (GCs), enhancing the generation of class-switched high-affinity antibodies. …”

Table_1_Myricetin Attenuated Diabetes-Associated Kidney Injuries and Dysfunction via Regulating Nuclear Factor (Erythroid Derived 2)-Like 2 and Nuclear Factor-κB Signaling.docx by Zi-Jun Yang (6822599)

“…Moreover, inhibition of IκB/NF-κB (P65) signaling pathway is independent of the regulation of Nrf2. Thus, Myr could be a potential treatment for preventing the development and progression of DM-associated kidney injuries and dysfunction.…”

Image_1_Twenty-Four Hour Blood Pressure Response to Empagliflozin and Its Determinants in Normotensive Non-diabetic Subjects.JPEG by Anne Zanchi (645982)

“…</p>Methods<p>In this post-hoc analysis of a double-blind, randomized, placebo-controlled study examining the renal effects of empagliflozin 10 mg vs. placebo in untreated normotensive non-diabetic subjects, the 1-month changes in 24 h ambulatory BP were analyzed in 39 subjects (13 placebo/26 empagliflozin) in regard to changes in biochemical and hormonal parameters.…”

Image_2_The aberrant dynamic amplitude of low-frequency fluctuations in melancholic major depressive disorder with insomnia.TIF by Zijing Deng (13276731)

“…Importantly, the right MTG/STG may play a critical role in patients with melancholic MDD with more severe insomnia.…”

Preservation of the activated PaDHPAO activity. by Soraya Pornsuwan (419434)

“…<p>(A) Percentage of relative activity of the activated PaDHPAO decreased after the solution was kept on ice for 7–8 hours in 50 mM potassium phosphate buffer, pH 7.0. …”

Image_1_Magnesium oxide nanoparticles reduce clubroot by regulating plant defense response and rhizosphere microbial community of tumorous stem mustard (Brassica juncea var. tumida... by Jingjing Liao (680851)

“…<p>Clubroot, caused by Plasmodiophora brassicae, is a major disease that significantly impairs the yield of cruciferous crops and causes significant economic losses across the globe. …”

Table1_Transition of dome formation to sudden explosive eruptions at Popocatépetl, Mexico: magnetic indicators.docx by Ana Lillian Martin-Del-Pozzo (18854692)

“…Some of the domes behaved as contained lava flows within the crater floor (pancakes) while others were more irregular-shaped. Activity decreased considerably over this 2019 interval except for the unexpected explosions in March and June, that produced ash plumes reaching up to 14,000 m a.s.l. …”

Gene expression analysis of nidus of cerebral arteriovenous malformations reveals vascular structures with deficient differentiation and maturation by Jaya Mary Thomas (5391239)

“…Immunofluorescent staining demonstrated that expression of KLF2, a vascular maturation marker is significantly (P <0.001) decreased in AVM vessels and was further confirmed by western blot analysis (P < 0.001). …”

Table_4_HOTAIR Up-Regulation Activates NF-κB to Induce Immunoescape in Gliomas.xlsx by Yunfei Wang (53741)

“…The long-stranded non-coding RNA HOTAIR is highly expressed and associated with metastasis in a variety of cancer types and promotes tumor metastasis at least in part through association with the PRC2 complex that induces redirection to hundreds of genes involved in tumor metastasis. …”

Image_2_Dietary Carbohydrate and Diverse Health Outcomes: Umbrella Review of 30 Systematic Reviews and Meta-Analyses of 281 Observational Studies.TIF by Ya-Shu Liu (10287695)

“…</p><p>Conclusions: Despite the fact that numerous systematic reviews and meta-analyses have explored the relationship between carbohydrate intake and diverse health outcomes, there is no convincing evidence of a clear role of carbohydrate intake. However, there is highly suggestive evidence suggested carbohydrate intake is associated with high risk of metabolic syndrome, suggestive evidence found its association with increased risk of all-cause mortality and decreased risk of esophageal adenocarcinoma.…”

Image_4_Physio-biochemical and transcriptomic analysis of Bacillus amyloliquefaciens PG-4-induced salt stress tolerance in Macrotyloma uniflorum.JPEG by Yanna Wu (7675676)

“…</p>Results<p>In presence of different salt levels, PG-4 showed a high potentiality to produce several plant growth promoting metabolites such as NH₃, siderophore, 1-aminocyclopropane-1-carboxylic acid deaminase (ACC-deaminase), and hydrolytic enzymes. …”

Image_2_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

Table_1_Effect of Lactobacillus johnsonii Strain SQ0048 on the TLRs-MyD88/NF-κB Signaling Pathway in Bovine Vaginal Epithelial Cells.docx by Chao Cheng (11274)

“…<p>Vaginal inflammation is a common disease of the dairy cows' reproductive tract. …”

After saphenous nerve injury GFRα2-positive neurons down-regulated GFRα2 and expressed GFRα3. by Ting Wang (16292)

“…<p>In naïve mice, IB₄-488-back-labeled neurons were immunopositive for GFRα2 (<b><i>A</i></b><b>, </b><b><i>B</i></b><b>, </b><b><i>D</i></b><b>;</b> arrows), but not GFRα3 (<b><i>E</i></b><b>, </b><b><i>F</i></b><b>, </b><b><i>H</i></b><b>;</b> arrows). …”

Table1_Network Pharmacology-Based Strategy for the Investigation of the Anti-Osteoporosis Effects and Underlying Mechanism of Zhuangguguanjie Formulation.DOCX by Wang Gong (11510329)

“…The ovariectomized (OVX) mice were treated with normal saline or ZG for 4 weeks after ovariectomy following a series of analyses. The bone mass density (BMD) and trabecular parameters were examined by micro-CT. …”

Video8_Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells.MP4 by Yuuki Shichi (13951587)

“…When forming spheres using low-attachment plates, most epithelial PDAC cell lines initially showed decreased sphere area, and then the covering cells fused to form a smooth surface on the sphere. …”

<i>as-</i>APF treatment antagonizes HB-EGF by regulation of MDM2 and p53. by Jayoung Kim (153487)

“…<p>(<b>A</b>) MDM2 expression is negatively correlated with p53 level. …”

Image_5_Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota... by Xiaoyu Gao (391492)

“…Importantly, we established a complex but clear network between gut microbiota and host parameters. …”

Image_6_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…The only drug that significantly decreased the blue-light aversion was the intraperitoneally injected melanopsin antagonist. …”

Involvement of Abscisic Acid in PSII Photodamage and D1 Protein Turnover for Light-Induced Premature Senescence of Rice Flag Leaves by Fubiao Wang (2994375)

“…The <i>psf</i> showed evidently decreased D1 protein amount in the senescent leaves. …”