Effects of ketamine and the established GSK-3 inhibitor SB216763 in the anhedonia model. by Xian-Cang Ma (285384)

“…<p>The decreased intake of 1% sucrose in the CMS groups was significantly attenuated 24 hours, 4 days, 6 days and 8 days after a single dose of ketamine (10 mg/kg, i.p.), but not of SB216763 (10 mg/kg, i.p.). …”

Table_1_Altered Gray Matter Volume in Patients With Type 1 Diabetes Mellitus.DOC by Jia Liu (41593)

“…The pooled meta-analyses detected that patients with T1DM showed robustly increased gray matter volume in the left dorsolateral superior frontal gyrus and middle frontal gyrus and a decreased gray matter volume in the right lingual gyrus, cerebellum, precuneus, the left inferior temporal gyrus, and middle temporal gyrus. …”

Table_1_Altered Gray Matter Volume in Patients With Type 1 Diabetes Mellitus.DOC by Jia Liu (41593)

“…The pooled meta-analyses detected that patients with T1DM showed robustly increased gray matter volume in the left dorsolateral superior frontal gyrus and middle frontal gyrus and a decreased gray matter volume in the right lingual gyrus, cerebellum, precuneus, the left inferior temporal gyrus, and middle temporal gyrus. …”

Sequential free body diagrams of frog jumping drawn according to Fig 2 to illustrate the interplay between the plantaris longus (PL) extensor moment, and the ground reaction force... by Eng Kuan Moo (3830128)

“…This process is accompanied by an increase in EMA [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173415#pone.0173415.ref007" target="_blank">7</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173415#pone.0173415.ref009" target="_blank">9</a>], with constant r_i [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173415#pone.0173415.ref010" target="_blank">10</a>] but a decrease in R_i. …”

The isolated Purkinje soma model bursts if the I_NaP and I_SK conductances are both set to 4 mS/cm². by Michael D. Forrest (292801)

“…<i>A</i>, Dendritically driven bursts in a full Purkinje cell model (described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068765#pone.0068765-Forrest1" target="_blank">[6]</a>) have a very stereotypical waveform with an ongoing increase in firing rate and termination by a more rapid increase in firing rate, with a decrease in spike height. …”

Temperature impacts oocyte heterogeneity before blood feeding. by In Hae Lee (19996735)

“…<p>A) Representative images of ovarioles from females at pre-blood meal, and 1, 3, 7, and 14 days after a blood meal housed in the conditions indicated. …”

Fig 7 - by Fiona J. Stenning (10987803)

“…<p>Mean blood flows in the umbilical vein (UV; open circles) and umbilical artery (UA; closed squares) measured immediately before (A) and during (B) consecutive uterine contractions before and after ventilation onset. …”

Pharmacologic TβRI inhibition increases trabecular bone volume. by Khalid S. Mohammad (120943)

“…<p>Micro-CT images show increased femoral trabecular bone volume following SD-208 treatment in male and female mice, relative to vehicle-treated controls (a). Quantitative analyses show that SD-208 increased trabecular bone volume (BV/TV, fraction) (b), connectivity density (c), and trabecular number (d), but decreased trabecular spacing (e) in male and female femora. …”

Chronic unpredictable mild stress (CUMS) leads the mice to express depression-like behaviors. by Ke Ma (260231)

“…Behavior tests showed the significant decreases in sucrose preference (a) and the ratios of stay time in M-arm to stay time in three arms (b) as well as the increase in immobile time (c) from CUMS-induced depression mice (n = 10) and controls (n = 11). …”

<i>Retun loss (RL)</i> and <i>f</i>_<i>min</i> of fluids exhibiting different polarities and osmolalities in comparison to purified water (aq. dest.) and phosphate buffer... by Rico Brendtke (2591161)

“…(D) <i>RL</i> decreased with a higher osmolality. Bar diagrams show mean values and error bars depict standard deviation. …”

Gene expression analysis of Wnt signalling in monolayer (Mono) and anoikis resistant (AR) cells of normal breast cell lines (N), ER-ve and ER+ve breast cancer cell lines. by Rebecca Lamb (105412)

“…B) Cluster analysis was performed using the fold change in expression between Mono and AR cells. Data is displayed in a heatmap represented by either decreased (green) or increased (red) expression compared to the mean mRNA expression. …”

Aerosol delivery of <i>C. neoformans</i> var. <i>grubii</i> yeast and yeast-spore mixtures. by Deborah J. Springer (217704)

“…(A) Increased tissue burden, dissemination to the brain, and (B) decreased weight was observed at 24 days post-exposure and demonstrates the developmental sequelae of cryptococcosis. …”

Linagliptin ameliorates albuminuria and kidney hypertrophy in DBA/2J diabetic mice but not in G6PD^- mice at 12 weeks. by Netanya Y. Spencer (5488931)

“…Urine ACR was significantly decreased in the DBA/2J linagliptin group (A). There was a trend of decreasing of urine ACR in WT-DM+Lina group (p = 0.088), but there was no change in G6PD deficient diabetic mice treated with linagliptin (B). …”

ORC2 knockdown enhances PV replication. by Marsha DeSmet (2513767)

“…Values are expressed as mean +/- SEM. * p-value ≤ 0.05. ORC2 shRNA decreased ORC2 protein expression in C33A cells. …”

MC-12 ameliorates colitis induced by both DSS and TNBS. by Nengtai Ouyang (148972)

“…<b><i>B:</i></b> Severe inflammation including infiltration by inflammatory cells, edema, loss of crypts and ulcerations are seen in a DSS + vehicle-treated mouse. <b><i>C, D:</i></b> MC-12, 5 or 25 mg/kg, IP, significantly decreased DSS-induced colonic inflammation. …”

The result of cell cycle distribution. by Zhe Chen (196097)

“…<p>The cell cycle distribution was detected by flowcytometry. (A,B)The proportion of G0/G1 phase cells increased and G2/M phase cells decreased in 5-8F and CNE2 cell lines as I3C concentration increased. …”

Table_4_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.DOCX by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Breadth and magnitude of CD8⁺ T-cell IFN-γ responses to clade-B consensus and autologous HIV-1 Nef peptides. by Mehrnoosh Doroudchi (118450)

“…<p>Frequencies and magnitudes of total Nef-specific CD8⁺ T-cell IFN-γ response to consensus and autologous HIV-Nef peptides by consensus peptides in high viremic subject (a) and low viremic subject (b). A decrease (#039) and an increase (#016) in the breadth of CD8⁺ T-cell responses to both consensus and autologous HIV-Nef sequences is shown during transition from primary (T1) to chronic (T2) infection. …”

Image 1_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…”

Image_2_Default Mode Network Complexity and Cognitive Decline in Mild Alzheimer’s Disease.tif by Matthias Grieder (5882825)

“…Potential associations of MSE with functional connectivity and cognitive abilities [i.e., mini-mental state examination (MMSE)] were assessed. A moderate decrease of DMN functional connectivity between posterior cingulate cortex and right hippocampus in Alzheimer’s disease was found, whereas no differences were evident for whole-network functional connectivity. …”