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145021
Baseline characteristics.
Published 2024“…<div><p>Background</p><p>Glenzocimab is a novel antithrombotic agent which targets platelet glycoprotein VI (GPVI) and does not induce haemorrhage. …”
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145022
Deregulation of Zeb-1 pathway in the inner-ears of Twirler mutant mice.
Published 2011“…<p>[A] Top panel – gene expression analysis of CD326-negative cells sorted from <i>Tw/Tw</i> mice show increase in epithelial specific markers in the <i>Tw/Tw</i> mutants compared with their wild type littermate controls. …”
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145023
(4,4) Rectangular Lattices of Cobalt(II) with 1,2,4,5-Benzenetetracarboxylic Acid: Influence of the Packing in the Crystal Structure
Published 2008“…The crystal structures of <b>1</b>−<b>3</b> consist of neutral square-grids of high-spin cobalt(II) ions with the fully deprotonated bta<sup>4−</sup> anion acting as a 4-fold connector. The interpenetration of two of these layers in <b>3</b> leads to a three-dimensional network. …”
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145024
Data_Sheet_7_Global, regional, and national burden of chronic respiratory diseases and associated risk factors, 1990–2019: Results from the Global Burden of Disease Study 2019.ZIP...
Published 2023“…</p>Results<p>In 2019, 454.56 [95% uncertainty interval (UI): 417.35–499.14] million individuals worldwide had a CRD, showing a 39·8% increase compared with 1990. …”
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145025
Table_1_Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 Patients.docx
Published 2021“…</p><p>Methods: We included 229 patients with confirmed COVID-19 in a multicenter, retrospective cohort study. Propensity score matching at a ratio of 1:3 was introduced to eliminate potential confounders. …”
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145026
Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx
Published 2025“…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. The present investigation was undertaken to evaluate the toxicological effects of (+)-gossypol powder, a substance derived from cottonseed in mice.…”
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145027
Table_6_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX
Published 2018“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”
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145028
Summary of the results identified in this manuscript through which NF-κB2 and RelB regulate p53 dependent cellular senescence in primary human NHD fibroblasts.
Published 2014“…<p>Depletion of NF-κB2 and RelB leads to a decrease in Rb phosphorylation. Unphosphorylated Rb represses E2F transcriptional activity and consequently inhibits EZH2 expression (which is negatively regulated by p53). …”
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145029
Enhanced proliferation and invasiveness in TKO tumors.
Published 2020“…</b> Western blot shows a decrease in E-cadherin and increases in vimentin and fibronectin protein expression in TKO cells, relative to DKO cells. …”
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145030
Image1_Modified Baihu decoction therapeutically remodels gut microbiota to inhibit acute gouty arthritis.PNG
Published 2022“…While the relative abundance of Lactobacillaceae, Erysipelotrichaceae, Ruminococcaceae, Prevotellaceae and Enterobacteriaceae showed a relative decrease in species abundance. Of these, the reduction in species abundance of Enterobacteriaceae was associated with a reduction in amino acid metabolism and environmental perception. …”
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145031
Data_Sheet_1_Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019.docx
Published 2022“…From 1990 to 2019, the DALYs of neurological diseases belonging to the communicable, maternal, neonatal and nutritional categories showed a sharp decrease, while Alzheimer's disease and other dementias and Parkinson's disease showed a large increase. …”
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145032
Table_4_Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients.docx
Published 2022“…</p>Results<p>We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”
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145033
RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5
Published 2017“…We have recently shown that a decrease in <i>RBM5</i> expression may be a key step in SCLC development, as RBM5 regulated many transformation-associated processes in SCLC cells. …”
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145034
Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets
Published 2015“…<div><p>Reprogramming of a gene’s expression pattern by acquisition and loss of sequences recognized by specific regulatory RNA binding proteins may be a major mechanism in the evolution of biological regulatory programs. …”
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145035
Table_1_Simultaneous Separation of Antioxidants and Carbohydrates From Food Wastes Using Aqueous Biphasic Systems Formed by Cholinium-Derived Ionic Liquids.pdf
Published 2019“…The development of sustainable and cost-effective technologies to recover these value added compounds will contribute to a significant decrease of the environmental footprint and economic burden of this industry sector. …”
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145036
Table_3_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX
Published 2018“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”
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145037
Table_3_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX
Published 2024“…</p>Results<p>Compared to the WT mice, PLP-cKO mice exhibited a significant decrease in motor and sensory conduction velocities, thermal sensitivity, and motor coordination. …”
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145038
Early-life iron deficiency persistently disrupts affective behaviour in mice
Published 2023“…</p> <p>Mothers receiving iron-deficient food during pregnancy and lactation exhibited significantly less licking and grooming behaviour, while active pup retrieval and pup ultrasonic vocalizations were unaltered. Adult offspring with a history of foetal and neonatal ID showed an increase in depression- and anxiety-like behaviour, paralleled by a deranged miRNA expression profile in the hippocampus, specifically levels of miR200a and miR200b.…”
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145039
Image_1_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.jpg
Published 2023“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”
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145040
Data_Sheet_3_Global, regional, and national burden of chronic respiratory diseases and associated risk factors, 1990–2019: Results from the Global Burden of Disease Study 2019.ZIP...
Published 2023“…</p>Results<p>In 2019, 454.56 [95% uncertainty interval (UI): 417.35–499.14] million individuals worldwide had a CRD, showing a 39·8% increase compared with 1990. …”