Data_Sheet_1_Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology.docx by Thamires Siqueira Oliveira (11398496)

“…Total and healthy mitochondria were reduced by 30% in septic mice, which may be associated with a 50% decrease in Ppargc1a (encoding PGC1a) and Opa1 (mitochondria fusion marker) expressions in the septic diaphragm. …”

Table_2_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX by Lei Wang (6656)

“…</p>Results<p>Compared to the WT mice, PLP-cKO mice exhibited a significant decrease in motor and sensory conduction velocities, thermal sensitivity, and motor coordination. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…In atherosclerotic lesions, no differences were observed in macrophage differentiation or VSMC content, although a small increase in collagen was identified.</p><p>Conclusion: Our data show that PCAF deficiency resulted in a decrease in circulatory FoxP3⁺ regulatory T cells and ameliorated atherosclerotic lesions with no differences in systemic inflammation or macrophage differentiation in the atherosclerotic lesions. …”

Efficient Direct H₂O₂ Synthesis Enabled by PdPb Nanorings via Inhibiting the O–O Bond Cleavage in O₂ and H₂O₂ by Kailei Cao (9962668)

“…We demonstrate that the preferential location of Pb species at the edge and corner can significantly decrease the amount of low-coordinated Pd atoms in Pd_<i>x</i>Pb NRs, leading to an enhanced H₂O₂ yield and selectivity but a reduced degradation rate. …”

Data_Sheet_5_Global, regional, and national burden of chronic respiratory diseases and associated risk factors, 1990–2019: Results from the Global Burden of Disease Study 2019.ZIP... by Xiang Chen (10398)

“…</p>Results<p>In 2019, 454.56 [95% uncertainty interval (UI): 417.35–499.14] million individuals worldwide had a CRD, showing a 39·8% increase compared with 1990. …”

DataSheet_1_Evaluation of 18F-FMISO PET and 18F-FDG PET Scans in Assessing the Therapeutic Response of Patients With Metastatic Colorectal Cancer Treated With Anti-Angiogenic Thera... by Sze Ting Lee (10316135)

“…Baseline FDG uptake was higher than FMISO uptake, and there was a significant decrease in FDG uptake (SUV_max and TGV) but not FMISO uptake (SUV_max and TNR) after treatment. …”

Image_4_Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures.TIFF by Lara M. Paulo (8567841)

“…For example, the main pH shock led to a drop in the methane content to 15%, COD removals decreased to 0%, while the archaeal population decreased to ~11% both at DNA and cDNA levels. …”

Study on the influence of seating orientation during frontal impacts by child occupant human body model response analysis by Mónica Diez (12118773)

“…Understanding child occupant responses under these new conditions is necessary to decrease risk and enhance child safety. In this study, child occupant response in different seating orientations exposed to frontal impacts with a focus on the head injuries and kinematics was analyzed.…”

Table_2_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

CD36 and Fyn Kinase Mediate Malaria-Induced Lung Endothelial Barrier Dysfunction in Mice Infected with <i>Plasmodium berghei</i> by Ifeanyi U. Anidi (446498)

“…To define the role that the scavenger receptor CD36 may play in mediating this response, C57BL/6J (WT) and CD36−/− mice were infected with <i>P. berghei</i> ANKA and monitored for changes in pulmonary endothelial barrier function employing an isolated perfused lung system. WT lungs demonstrated a >10-fold increase in two measures of paracellular fluid conductance and a decrease in the albumin reflection coefficient (σ_alb) compared to control lungs indicating a loss of barrier function. …”

Transcription of Biotic Stress Associated Genes in White Clover (<i>Trifolium repens L</i>.) Differs in Response to Cyst and Root-Knot Nematode Infection by Afsana Islam (798416)

“…Invasion by the CRKN resulted in a significant decrease in transcript abundance of <i>Tr-KPI4</i> locally at both 4 days post-infection (dpi) and at 8 dpi, and an increase in transcription of <i>Tr-KPI1</i> systemically at 8 dpi. …”

DataSheet1_BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells.docx by María Benito-León (544046)

“…BCI enhanced dual specificity phosphatase 1 expression, whereas it induced a decrease in the dual specificity phosphatase 6 transcripts, suggesting that BCI-dependent inhibition of dual specificity phosphatase 1 may be responsible for the increase in p38 and JNK phosphorylation. …”

Table_2_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.DOCX by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Table_1_Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis.xlsx by Roel Bijkerk (4662769)

“…In order to identify pericyte long non-coding RNAs (lncRNAs) that could serve as a target to decrease myofibroblast formation and counteract the progression of kidney fibrosis we employed two models of experimental kidney injury, one focused on kidney fibrosis (unilateral ureteral obstruction; UUO), and one focused on acute kidney injury that yields kidney fibrosis in the longer term (unilateral ischemia-reperfusion injury; IRI). …”

Table_1_Luteolin Modulates Neural Stem Cells Fate Determination: In vitro Study on Human Neural Stem Cells, and in vivo Study on LPS-Induced Depression Mice Model.pdf by Mariem Achour (11630299)

“…We found that oral administration of luteolin (10 mg/Kg) for eight consecutive days could decrease the immobility time on tail suspension test, a mouse behavioral test measuring depression-like behavior, and attenuate LPS-induced inflammatory responses by significantly decreasing IL-6 production in mice brain-derived astrocytes and serum, and TNFα and corticosterone levels in serum. …”

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein by Linyuan Feng (4804452)

“…Thus, UL23 appears to interact directly with Nmi and inhibit nuclear translocation of Nmi and its associated protein STAT1, leading to a decrease of IFN-γ induced responses and an increase of viral resistance to IFN-γ. …”

Data_Sheet_1_Association Between Response to Nivolumab Treatment and Peripheral Blood Lymphocyte Subsets in Patients With Non-small Cell Lung Cancer.docx by Selene Ottonello (8416638)

“…<p>Immune checkpoint blockade represents a major breakthrough in advanced non-small cell lung cancer (NSCLC) therapy. …”

DataSheet_1_Exploring preferences of different modes of administration of hypomethylating agent treatments among patients with acute myeloid leukemia.pdf by Audrey Delmas (6237905)

“…Hypomethylating Agents (HMAs) intravenously (IV) or subcutaneously (SC) in a clinical setting are typically offered as an alternative. …”

Actionable Gene Expression-Based Patient Stratification for Molecular Targeted Therapy in Hepatocellular Carcinoma by Jung-Hee Kwon (421854)

“…Up-regulation of EGFR was observed at early stage and tended to gradually decrease toward late stages (BCLC stage A: 41.9%; B: 30.8%; C: 17.6%). …”

Image_1_Tumor-Derived Exosomes Enriched by miRNA-124 Promote Anti-tumor Immune Response in CT-26 Tumor-Bearing Mice.TIF by Ramazan Rezaei (8192640)

“…Significant tumor growth inhibition and increased median survival time was achieved in tumor-bearing mice treated with TEXomiR. A significant decrease in CD4/CD8 and Treg/CD8 ratio in tumor tissue was demonstrated. …”