Image 12_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Image_3_B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.tif by Christopher Tay (335988)

“…These findings suggest that targeting B cell and CD4 T cell interaction may be a therapeutic strategy to limit atherosclerosis progression.…”

Data_Sheet_7_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP by Zhi Liu (165121)

“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”

Presentation_3_Precision immunointerception of EGFR-driven tumorigenesis for lung cancer prevention.pptx by Jing Pan (95938)

“…In this study, we identified immunogenic epitopes for the common EGFR mutations in humans and formulated a multi-peptide vaccine (E^mut Vax) targeting the EGFR L858R, T790M, and Del19 mutations. …”

Table_6_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.xlsx by Jiarui Mi (11170284)

“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”

DataSheet_1_Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.pdf by Yu Xiao (150812)

“…<p>Chronic inflammation is widely observed in aging, but it is unclear whether extracellular vesicles (EVs) play a role in chronic disease-associated senescence. …”

DataSheet2_Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα).doc... by Min Zhang (111999)

“…<p>Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. …”

Data_Sheet_1_Bilateral Superior Cervical Sympathectomy Activates Signal Transducer and Activator of Transcription 3 Signal to Alleviate Myocardial Ischemia-Reperfusion Injury.pdf by Lixia Li (407712)

“…Studies have increasingly found that the signal transducer and activator of transcription 3 (STAT3) plays a protective role in myocardial I/R injury. However, the precise mechanism is unknown. …”

Video_1_Surface-Induced Formation and Redox-Dependent Staining of Outer Membrane Extensions in Shewanella oneidensis MR-1.AVI by Grace W. Chong (7311689)

“…While previous studies focused on the display of S. oneidensis outer membrane extensions (OMEs) as a response to oxygen limitation, we find that cell-to-surface contact is sufficient to trigger the production of OMEs, including some that reach >100 μm in length, irrespective of medium composition, agitation, or aeration. …”

DataSheet_2_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx by Júlia Teixeira Cottas de Azevedo (11816621)

“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”

The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation by Amandeep Singh (3511400)

“…Taken together, our study describes a new function for BNIP3 in the regulation of cellular proliferation.…”

DataSheet1_Eastward Jet Lag is Associated with Impaired Performance and Game Outcome in the National Basketball Association.pdf by Josh Leota (11852359)

DataSheet1_Metformin reduces basal subpopulation and attenuates mammary epithelial cell stemness in FVB/N mice.docx by Minghui Shan (19068320)

“…These insights suggest that the regulatory effects of metformin on premalignant mammary tissues could potentially delay or prevent the onset of breast cancer, offering a promising avenue for developing new preventive strategies.…”

Data_Sheet_1_Cost-effectiveness of Paxlovid in reducing severe COVID-19 and mortality in China.docx by Weina Zhang (128757)

“…</p>Materials and methods<p>Using a Markov model, two interventions by Paxlovid prescription (with and without prescription) were compared in terms of COVID-19-related clinical outcomes and economic loss. …”

Spatially Extensive Standardized Surveys Reveal Widespread, Multi-Decadal Increase in East Antarctic Adélie Penguin Populations by Colin Southwell (289714)

“…East Antarctic marine ecosystems have been subject to a number of changes over the last 50 years which may have influenced Adélie penguin population growth, including decadal-scale climate variation, an inferred mid-20th century sea-ice contraction, and early-to-mid 20^th century exploitation of fish and whale populations.…”

Table_2_Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice.DOCX by Naoki Sasaki (791369)

“…Endotoxemia was induced in C57BL/6J mice (8 weeks old) by intravenous injection of sonicated Pg; Pg was deactivated but its endotoxin remained. The mice were fed a high-fat diet and administered sonicated Pg (HFPg) or saline (HFco) injections for 12 weeks. …”

Table 2_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…However, the specific effects of different drainage durations on soil microorganisms and metabolites remain unclear. This study adopted a multi-omics research method. After nontargeted metabolomics analysis of lipids as the main metabolite, microbial diversity analysis and lipidomics analysis were conducted to determine the main influencing factors. …”

Staphylococcal Peptidoglycan Co-Localizes with Nod2 and TLR2 and Activates Innate Immune Response via Both Receptors in Primary Murine Keratinocytes by Maria Anna Müller-Anstett (240399)

“…To support the data, co-localization and signaling studies were carried out with SHL-PGN, a lipase protein covalently tethered to PGN-fragments of varying sizes at its C-terminus. …”

DataSheet_1_The asymmetric photosynthetic characteristics of the isobilateral sorghum leaves under the illumination of the diffuse light.pdf by Xiaolin Wang (303612)

“…Because of the current changing fraction of diffuse light in sky radiation, this study investigated the dorsoventral asymmetry of photosynthetic traits under direct and diffuse light conditions in an important food and energy crop, Sorghum bicolor L. A unique method was used to investigate the specific gas exchange of each leaf surface. …”

The prediction and confirmation of the <i>miR-101</i> target. by Rui Wang (52434)

“…<p>(A) <i>MiR-101</i> binding sites in the 3′-UTR region of <i>Stmn1</i> in cross-species. …”