Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer by Kelly Coffey (129302)

“…<div><p>Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling. …”

Epidemiology of harmful use of alcohol in Nigeria: a systematic review and meta-analysis by Davies Adeloye (589375)

“…<p><i>Background</i>: Nigeria, the most populous country in Africa, has reported relatively high levels of alcohol misuse, yet limited resources to guide effective population-wide response. There is a need to integrate existing empirical information in order to increase the power and precision of estimating epidemiological evidence necessary for informing policies and developing prevention programs.…”

Table_1_Cathepsins and cancer risk: a Mendelian randomization study.xlsx by Tingting Deng (606369)

“…Background<p>Previous observational epidemiological studies reported an association between cathepsins and cancer, however, a causal relationship is uncertain. This study evaluated the causal relationship between cathepsins and cancer using Mendelian randomization (MR) analysis.…”

Ligand Aspect Ratio as a Decisive Factor for the Self-Assembly of Coordination Cages by Suzanne M. Jansze (1403719)

“…This point is demonstrated for a series of iron- and palladium-based coordination cages. …”

Ligand Aspect Ratio as a Decisive Factor for the Self-Assembly of Coordination Cages by Suzanne M. Jansze (1403719)

“…This point is demonstrated for a series of iron- and palladium-based coordination cages. …”

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity by Shubha Murthy (4529191)

“…<div><p>The multifunctional Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine kinase important in transducing intracellular Ca²⁺ signals. …”

Flammability thresholds of Eastern redcedar as a potential indicator for heightened wildfire danger by Christine H. Bielski (5026868)

“…This data publication includes flammability measurements for 100 Eastern redcedar twigs across a foliar moisture content gradient ranging from 0% to 180%. …”

Decline of physical activity in early adolescence: A 3-year cohort study by Vedrana Sember (8561436)

“…<div><p>This study analyses the changes of moderate-to-vigorous physical activity (MVPA) in a cohort of boys and girls aged 11 (n = 50) and 14 (n = 50). …”

NRF2 deficiency increases obesity susceptibility in a mouse menopausal model by Xunwei Wu (5172356)

“…In conclusion, the combination of <i>Nrf2</i> deletion and a decline in estrogen level induced a significant increase in bodyweight, which may be associated with their altered glucose and LDL metabolism and decreased 5-HT levels. …”

Virus Infection of Plants Alters Pollinator Preference: A Payback for Susceptible Hosts? by Simon C. Groen (496038)

“…Virus-induced quantitative and qualitative changes in blends of volatile organic compounds emitted by tomato plants were identified by gas chromatography-coupled mass spectrometry. Experiments with a CMV mutant unable to express the 2b RNA silencing suppressor protein and with Arabidopsis silencing mutants implicate microRNAs in regulating emission of pollinator-perceivable volatiles. …”

Galectin-2 Induces a Proinflammatory, Anti-Arteriogenic Phenotype in Monocytes and Macrophages by Cansu Yıldırım (725560)

“…<div><p>Galectin-2 is a monocyte-expressed carbohydrate-binding lectin, for which increased expression is genetically determined and associated with decreased collateral arteriogenesis in obstructive coronary artery disease patients. …”

IAV performs a receptor concentration-driven random walk on the plasma membrane. by Christian Sieben (549611)

“…From our simulated data, correlation of D_conf with the dwell time shows that a local increase in AF concentration (i.e. decreased diffusion) due to the encounter of an SA nanodomain leads to an increased local dwell time (<b>H</b>, red markers). …”

Growth Differentiation Factor 6 As a Putative Risk Factor in Neuromuscular Degeneration by Michèle G. DuVal (278183)

“…Fish lacking <i>gdf6a</i> exhibited decreased endurance (∼50%, p = 0.005) compared to wild type, and this deficit progressively worsened with age. …”

Albendazole and Corticosteroids for the Treatment of Solitary Cysticercus Granuloma: A Network Meta-analysis by Bing-Cheng Zhao (2155732)

“…Several different treatment options exist for SCG. We conducted a Bayesian network meta-analysis of randomized clinical trials (RCTs) to identify the best treatment option to prevent seizure recurrence and promote lesion resolution for patients with SCG.…”

Supplementary Material for: Clusters of Severe Eosinophilic Asthma in a Korean Asthma Cohort by Lee J.-H. (3189423)

Ocean acidification modulates expression of genes and physiological performance of a marine diatom by Yahe Li (564095)

“…The expression of the genes encoding fucoxanthin chlorophyll <i>a</i>/<i>c</i> protein (lhcf type (<i>fcp</i>)), mitochondrial ATP synthase (<i>mtATP</i>), ribulose-1, 5-bisphosphate carboxylase/oxygenase large subunit gene (<i>rbcl</i>) and NADH dehydrogenase subunit 2 (<i>ndh</i>2), were down-regulated during the first four days (< 8 generations) after the cells were transferred from LC (cells grown under ambient air condition; 390 μatm; pH_nbs 8.19) to OA conditions, with no significant difference between LC and HC treatments with the time elapsed. …”

Molecular Dynamics Simulations of GABA_A receptors with T3 bound. by Thomas Westergard (801745)

“…D) Total energy of T3 molecules across trajectory, relative to that of the β-α interface shown in first column and in Panel C, and in left to right order of increasing average energy/decreasing favorability. Energy trajectories were smoothed with a 20 ns window, with the initial and final 20 ns removed due to distortion from the windowing process. …”

Characterization of JTA009, a novel anti-human ICOS mAb by Manabu Kawamoto (18939)

“…</p><p>Published online 22 Mar 2006</p><p>PMCID:PMC1526621.</p><p></p> JTA009, a fully human anti-human ICOS mAb, has greater avidity than SA12. …”

Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis by Alexander F. Flynn (7377575)

“…<div><p>Lymphatic filariasis (LF), a morbid disease caused by the tissue-invasive nematodes <i>Wuchereria bancrofti</i>, <i>Brugia malayi</i>, and <i>Brugia timori</i>, affects millions of people worldwide. …”

Cooperative Interactions with Water Drive Hysteresis in a Hydrophilic Metal–Organic Framework by Julius J. Oppenheim (4744359)

“…Even though the theoretical factors that affect hysteresis are understood, understanding the structure–function correlations that dictate the hysteretic behavior in water sorbents remains a challenge. Herein, we synthesize a new hexagonal microporous framework, Ni₂Cl₂BBTQ (H₂BBTQ = 2<i>H</i>,6<i>H</i>-benzo[1,2-<i>d</i>][4,5-<i>d</i>′]bistriazolequinone), to elucidate these principles. …”